Angela Carter's focus on celluloid dreams

Santamaría, José Miguel; Pajares, Eterio; Olsen, Vickie; Merino, Raquel; Eguíluz, Federico (eds.)

Goi mailako errugbi talde batean aurredenboraldiaren efektuak zineantropometria, gorputz osaera eta somatotipoan

Ikerketa lan honen helburu nagusia, Espainiako maila gorenean jokatzen aritzen den Getxo Errugbi taldeko jokalarien estruktura biotipologikoa eta somatotipoa aztertzea eta aurre-denboraldian zehar, hau da, 10 astetan zehar gorputz egituran jasandako aldaketak baloratzea izan da. Bestalde, aurrelarien eta atzelarien arteko desberdintasunak eta postuaren arabera aurre-denboraldiak duen eragina sumatzearen helburua ere izan du ikerketa honek. Horretarako, aurre-denboraldiaren hasieran, ekainaren 18an eta amaieran, abuztuaren 27an, elite mailako diren 30 jokalariren datu antropometrikoak neurtu izan ziren. Datu antropometrikoak altuera, pisua, larruazaleko tolesturak, hezur diametroak eta gorputz adarren perimetroak izan ziren. 30 jokalarien ekaineko batez besteko adina, esperientzia, altuera, pisua, gorputz masa indizea eta gantz ehunekoa hurrengokoak izan ziren hurrenez hurren; 25,7 ?? 5,7 urte, 14,3 ?? 6,1 urte, 181,5 ?? 6,8 cm, 91,2 ?? 17,7 kg, 27,6 ?? 4,6 GMI eta 13,48 ?? 3,66 gantz %. Metodologiari dagokionez, kirolari bakoitzaren somatotipoa Heath-Carter metodoaren bidez kalkulatua izan da eta gantz ehunekoa eta gantz masa 4 gunetako Jackson/Pollock gantz kalibre metodoaren bidez kalkulatu izan dira.

Políticas públicas y cooperación con agentes externos en procesos de innovación: estudio comparado de pymes industriales en tres sistemas regionales

Este trabajo se ha efectuado en el marco del proyecto con referencia: CSO2011-29410-C03-01.Convocatoria del Subprograma de Proyectos de Investigación Fundamental no orientada del Ministerio de Economía y Competitividad

Alcohol-Related Brain Damage in Humans

Chronic excessive alcohol intoxications evoke cumulative damage to tissues and organs. We examined prefrontal cortex (Brodmann's area (BA) 9) from 20 human alcoholics and 20 age, gender, and postmortem delay matched control subjects. H & E staining and light microscopy of prefrontal cortex tissue revealed a reduction in the levels of cytoskeleton surrounding the nuclei of cortical and subcortical neurons, and a disruption of subcortical neuron patterning in alcoholic subjects. BA 9 tissue homogenisation and one dimensional polyacrylamide gel electrophoresis (PAGE) proteomics of cytosolic proteins identified dramatic reductions in the protein levels of spectrin beta II, and alpha- and beta-tubulins in alcoholics, and these were validated and quantitated by Western blotting. We detected a significant increase in a-tubulin acetylation in alcoholics, a non-significant increase in isoaspartate protein damage, but a significant increase in protein isoaspartyl methyltransferase protein levels, the enzyme that triggers isoaspartate damage repair in vivo. There was also a significant reduction in proteasome activity in alcoholics. One dimensional PAGE of membrane-enriched fractions detected a reduction in beta-spectrin protein levels, and a significant increase in transmembranous alpha 3 (catalytic) subunit of the Na+, K+-ATPase in alcoholic subjects. However, control subjects retained stable oligomeric forms of a-subunit that were diminished in alcoholics. In alcoholics, significant loss of cytosolic alpha-and beta-tubulins were also seen in caudate nucleus, hippocampus and cerebellum, but to different levels, indicative of brain regional susceptibility to alcohol-related damage. Collectively, these protein changes provide a molecular basis for some of the neuronal and behavioural abnormalities attributed to alcoholics