Double layers in gravity theories

Gravitational double layers, unlike their classical electromagnetic counterparts, are thought to be forbidden in gravity theories. It has been recently shown, however, that they are feasible in, for instance, gravity theories with a Lagrangian quadratic in the curvature. This is surprising with many potential consequences and the possibility of new physical behaviours. While a clear interpretation seems elusive, several lines of research are open. I present the field equations for double layers, the new physical quantities arising, and several explicit examples

Randomized, double-blind, placebo-controled clinical trial of sublingual immunotherapy in natural rubber latex allergic patients

Trial registration number: CTRN12611000543987

Dibujo infantil y cultura visual: estudios de género en las series de animación, representación e interpretación por parte de los propios niños

Ponencia leída en el Foro de Comunicaciones IkasArt II (BEC Barakaldo, 2010.06.18)

Radiotherapy plus nimotuzumab or placebo in the treatment of high grade glioma patients: results from a randomized, double blind trial

Background The prognosis of patients bearing high grade glioma remains dismal. Epidermal Growth Factor Receptor (EGFR) is well validated as a primary contributor of glioma initiation and progression. Nimotuzumab is a humanized monoclonal antibody that recognizes the EGFR extracellular domain and reaches Central Nervous System tumors, in nonclinical and clinical setting. While it has similar activity when compared to other anti-EGFR antibodies, it does not induce skin toxicity or hypomagnesemia. Methods A randomized, double blind, multicentric clinical trial was conducted in high grade glioma patients (41 anaplastic astrocytoma and 29 glioblastoma multiforme) that received radiotherapy plus nimotuzumab or placebo. Treatment and placebo groups were well-balanced for the most important prognostic variables. Patients received 6 weekly doses of 200 mg nimotuzumab or placebo together with irradiation as induction therapy. Maintenance treatment was given for 1 year with subsequent doses administered every 3 weeks. The objectives of this study were to assess the comparative overall survival, progression free survival, response rate, immunogenicity and safety. Results The median cumulative dose was 3200 mg of nimotuzumab given over a median number of 16 doses. The combination of nimotuzumab and RT was well-tolerated. The most prevalent related adverse reactions included nausea, fever, tremors, anorexia and hepatic test alteration. No anti-idiotypic response was detected, confirming the antibody low immunogenicity. The mean and median survival time for subjects treated with nimotuzumab was 31.06 and 17.76 vs. 21.07 and 12.63 months for the control group. Conclusions In this randomized trial, nimotuzumab showed an excellent safety profile and significant survival benefit in combination with irradiation.

Pumped double quantum dot with spin-orbit coupling

We study driven by an external electric field quantum orbital and spin dynamics of electron in a one-dimensional double quantum dot with spin-orbit coupling. Two types of external perturbation are considered: a periodic field at the Zeeman frequency and a single half-period pulse. Spin-orbit coupling leads to a nontrivial evolution in the spin and orbital channels and to a strongly spin-dependent probability density distribution. Both the interdot tunneling and the driven motion contribute into the spin evolution. These results can be important for the design of the spin manipulation schemes in semiconductor nanostructures.

Análisis de series temporales : modelos ARIMA

Este documento es de utilidad como material docente a cualquier estudiante o persona interesada que quiera introducirse en el estudio del análisis de series temporales. Puede ser utilizado como libro de texto en algunas de las asignaturas que se imparten en la licenciatura en Economía y en la licenciatura en Administración de Empresas. Los modelos de series temporales ARIMA constituyen el núcleo del contenido de este documento. Estos modelos se basan en la teoría de los procesos estocásticos que se desarrolla en el capítulo 2. Los modelos ARMA estacionarios se explican con detalle en el capítulo 3 y los modelos ARIMA no estacionarios en el capítulo 4. La metodología de modelización ARIMA con las fases de identificación, estimación y contraste de diagnósticos se explica detalladamente en el capítulo 5 y el capítulo 6 se dedica a la predicción. El capítulo 7 trata sobre la especificación de los modelos de series temporales adecuados a los datos estacionales. Por último, el capítulo 8 reúne una colección de ejercicios para el trabajo propio del lector.

Estudio de series temporales y composición química del material particulado atmosférico en distintas áreas del País Vasco

286 p. : il. col.

Hunting spectro-temporal information in unevenly spaced paleoclimate time series

18 p.