All the King's Men: del Pulitzer al Oscar

Eterio Pajares, Raquel Merino y José Miguel Santamaría (eds.)

Dispersión urbana en el Suelo No Urbanizable del País Vasco: la distorsión del planeamiento en la Reserva de la Biosfera de Urdaibai

Creative Commons Reconocimiento-NoComercial 3.0 España

Classification of neocortical interneurons using affinity propagation

In spite of over a century of research on cortical circuits, it is still unknown how many classes of cortical neurons exist. Neuronal classification has been a difficult problem because it is unclear what a neuronal cell class actually is and what are the best characteristics are to define them. Recently, unsupervised classifications using cluster analysis based on morphological, physiological or molecular characteristics, when applied to selected datasets, have provided quantitative and unbiased identification of distinct neuronal subtypes. However, better and more robust classification methods are needed for increasingly complex and larger datasets. We explored the use of affinity propagation, a recently developed unsupervised classification algorithm imported from machine learning, which gives a representative example or exemplar for each cluster. As a case study, we applied affinity propagation to a test dataset of 337 interneurons belonging to four subtypes, previously identified based on morphological and physiological characteristics. We found that affinity propagation correctly classified most of the neurons in a blind, non-supervised manner. In fact, using a combined anatomical/physiological dataset, our algorithm differentiated parvalbumin from somatostatin interneurons in 49 out of 50 cases. Affinity propagation could therefore be used in future studies to validly classify neurons, as a first step to help reverse engineer neural circuits.

Revisión y adecuación del estilo asesor : estudio sobre la actuación e incidencia del asesoramiento educativo en el berritzegune B06 Basauri-Galdakao

337 p. : il.

Euskadi Irratiko (EITB) eta Radio nan Gàidheal-go (BBC ALBA) kazetarien profil eta jarreren alderaketa

337 p.

Optimisation of the first principle code Octopus for massive parallel architectures: application to light harvesting complexes

150 p.

Spatial-temporal excess mortality patterns of the 1918-1919 influenza pandemic in Spain

Background: The impact of socio-demographic factors and baseline health on the mortality burden of seasonal and pandemic influenza remains debated. Here we analyzed the spatial-temporal mortality patterns of the 1918 influenza pandemic in Spain, one of the countries of Europe that experienced the highest mortality burden. Methods: We analyzed monthly death rates from respiratory diseases and all-causes across 49 provinces of Spain, including the Canary and Balearic Islands, during the period January-1915 to June-1919. We estimated the influenza-related excess death rates and risk of death relative to baseline mortality by pandemic wave and province. We then explored the association between pandemic excess mortality rates and health and socio-demographic factors, which included population size and age structure, population density, infant mortality rates, baseline death rates, and urbanization. Results: Our analysis revealed high geographic heterogeneity in pandemic mortality impact. We identified 3 pandemic waves of varying timing and intensity covering the period from Jan-1918 to Jun-1919, with the highest pandemic-related excess mortality rates occurring during the months of October-November 1918 across all Spanish provinces. Cumulative excess mortality rates followed a south-north gradient after controlling for demographic factors, with the North experiencing highest excess mortality rates. A model that included latitude, population density, and the proportion of children living in provinces explained about 40% of the geographic variability in cumulative excess death rates during 1918-19, but different factors explained mortality variation in each wave. Conclusions: A substantial fraction of the variability in excess mortality rates across Spanish provinces remained unexplained, which suggests that other unidentified factors such as comorbidities, climate and background immunity may have affected the 1918-19 pandemic mortality rates. Further archeo-epidemiological research should concentrate on identifying settings with combined availability of local historical mortality records and information on the prevalence of underlying risk factors, or patient-level clinical data, to further clarify the drivers of 1918 pandemic influenza mortality.

¿Uno o dos frunimianos en 'Vita Emiliani' y cartas de Braulio de Zaragoza?

[EN] We try to prove, with arguments taken from the texts, that the person named "Fruinianus", to whom Braulio de Saragossa addresses his letters XIII and XIV in his epistolary, is the same Frunimianus as the one from the introductory letter to 'Vita Emiliani', that is, Braulio's brother.

Le système monétaire international comme facteur d'instabilité: une ébauche de réforme

371 p.

Dinámica poblacional, características clínicas, sensibilidad antimicrobiana y tipado molecular de la infección gonocócica: estudio clínico y epidemiológico en el área de Bilbao

191 p.

Inscripciones romanas de Segovia, III: "addenda et corrigenda" a «Epigrafía romana de Segovia y su provincia»

[ES] En este artículo presentamos nuestra tercera aportación de novedades de la epigrafía de época romana de la provincia de Segovia, con seis piezas nuevas, recogemos dos ya publicadas, de una aportamos nueva lectura e interpretación, e introducimos un apartado de corrigenda con dos entradas.

Tibulo en la literatura europea (con especial atención a la inglesa): la pervivencia de la elegía latina

[ES] Este trabajo muestra ejemplos de la difusión que, como modelo, ha tenido el "corpus Tibullianum" en la poesía de Occidente. Ponemos de relieve su apreciación en Inglaterra, donde hemos encontrado un interesante grupo tanto de imitaciones expresas y como de composiciones de diverso signo que se aproximan a la elegía latina a través de Tibulo. La mayor parte de estos testimonios se sitúan en los siglos XVlI y XVIII, coincidiendo con las primeras traducciones inglesas, y terminan con los poetas románticos, que como Byron ya adelantan la actitud de nuestro tiempo ante el "corpus Tibullianum", entre un cierto olvido y admiración.