Running Pace Decrease during a Marathon Is Positively Related to Blood Markers of Muscle Damage

Background: Completing a marathon is one of the most challenging sports activities, yet the source of running fatigue during this event is not completely understood. The aim of this investigation was to determine the cause(s) of running fatigue during a marathon in warm weather. Methodology/Principal Findings: We recruited 40 amateur runners (34 men and 6 women) for the study. Before the race, body core temperature, body mass, leg muscle power output during a countermovement jump, and blood samples were obtained. During the marathon (27 uC; 27% relative humidity) running fatigue was measured as the pace reduction from the first 5-km to the end of the race. Within 3 min after the marathon, the same pre-exercise variables were obtained. Results: Marathoners reduced their running pace from 3.5 6 0.4 m/s after 5-km to 2.9 6 0.6 m/s at the end of the race (P,0.05), although the running fatigue experienced by the marathoners was uneven. Marathoners with greater running fatigue (. 15% pace reduction) had elevated post-race myoglobin (1318 6 1411 v 623 6 391 mg L21; P,0.05), lactate dehydrogenase (687 6 151 v 583 6 117 U L21; P,0.05), and creatine kinase (564 6 469 v 363 6 158 U L21; P = 0.07) in comparison with marathoners that preserved their running pace reasonably well throughout the race. However, they did not differ in their body mass change (23.1 6 1.0 v 23.0 6 1.0%; P = 0.60) or post-race body temperature (38.7 6 0.7 v 38.9 6 0.9 uC; P = 0.35). Conclusions/Significance: Running pace decline during a marathon was positively related with muscle breakdown blood markers. To elucidate if muscle damage during a marathon is related to mechanistic or metabolic factors requires further investigation.

La investigación naturalista e interpretativa desde la actividad física y el deporte

[Es]Desde este artículo se revisan diversos estudios de investigación relativos a la sublínea de formación del profesorado de educación física y deportiva, así como a la intervención docente en esta área de conocimientos. Esta sublínea se enmarca en la línea de Actividad Física y Deportes en el área de Didáctica de la Expresión Corporal. En este caso, se incluyen estudios de carácter naturalista e interpretativo, con la intención de que las personas que investigan y sus protagonistas formen parte activa en el propio proceso investigador (Bodgan y Biklen, 1982; Colás y Buendía, 1992; Goetz y Lecompte, 1988; Vázquez y Angulo, 2003). La formación del profesorado de educación física y la actividad didáctica de dicha materia, se convierten en los contenidos que concretan el proceso de la investigación. Para ello, es preciso revisar las temáticas relacionadas con: la formación inicial y permanente, planes y programas de estudio, contenidos que se enseñan y aprenden en la actividad física escolar (dentro y fuera del horario lectivo), la presencia de los valores, los diferentes elementos que constituyen los diseños curriculares, así como todo, aquello que convierte a esta disciplina en una destacada propuesta formativa y de socialización.

[R_Clavijo_SanPrudencio] Intensive Program ERASMUS: TOPCART. Geometric Documentation of the Heritage (report of activities 2010-2011)

[EN] Data contained in this record come from the following accademic activity (from which it is possible to locate additional records related with the Monastery):

In vitro activities of natural products against oral Candida isolates from denture wearers

Background: Candida-associated denture stomatitis is a frequent infectious disease. Treatment of this oral condition is difficult because failures and recurrences are common. The aim of this study was to test the in vitro antifungal activity of pure constituents of essentials oils. -- Methods: Eight terpenic derivatives (carvacrol, farnesol, geraniol, linalool, menthol, menthone, terpinen-4-ol, and aterpineol), a phenylpropanoid (eugenol), a phenethyl alcohol (tyrosol) and fluconazole were evaluated against 38 Candida isolated from denture-wearers and 10 collection Candida strains by the CLSI M27-A3 broth microdilution method. -- Results: Almost all the tested compounds showed antifungal activity with MIC ranges of 0.03-0.25% for eugenol and linalool, 0.03-0.12% for geraniol, 0.06-0.5% for menthol, a-terpineol and terpinen-4-ol, 0.03-0.5% for carvacrol, and 0.06-4% for menthone. These compounds, with the exception of farnesol, menthone and tyrosol, showed important in vitro activities against the fluconazole-resistant and susceptible-dose dependent Candida isolates. -- Conclusions: Carvacrol, eugenol, geraniol, linalool and terpinen-4-ol were very active in vitro against oral Candida isolates. Their fungistatic and fungicidal activities might convert them into promising alternatives for the topic treatment of oral candidiasis and denture stomatitis.

La actividad del World Café, una herramienta para la evaluación y desarrollo de los valores en el deporte escolar

[ES] El presente trabajo presenta una experiencia aplicada que pretende conocer las opiniones, de los agentes sociales que rodean a los jóvenes deportistas, para la promoción de valores. A través de la actividad del World Café, los agentes sociales implicados en el deporte escolar aportaron orientaciones enfocadas a mejorar la calidad educativa del deporte. Un grupo de 56 participantes [padres/madres (8), árbitros (8), profesores de educación física (8), entrenadores (8), deportistas de élite (8), deportistas escolares (8) y representantes institucionales (8)] debatieron, desde su perspectiva, cómo consideraban que podían ayudar en la promoción de valores en los contextos deportivos escolares en los que participan. Entre los resultados más relevantes destacan, la necesidad de concretar desde el propio centro escolar los valores que se pretenden promocionar a través del deporte; en segundo lugar, la importancia de llevar a cabo una coordinación entre los agentes directos que rodean a los jóvenes deportistas; y finalmente, llevar a cabo una formación dirigida a monitores y padres/madres, que les permita adquirir herramientas adecuadas para la promoción de valores.

The deliberate practice: the sports excellence versus the musical excellence

[ENG] If we look around us, we can observe that there is someone who is the best in each field of activity. We could think that they are exceptional individuals. This Final Project aims to increase knowledge of the effects of Deliberate Practice in the domains of music and sport. This will define you a concept of Deliberate Practice and then focus on the diversity of situations in which it shows us how it is presented in real life. From a questionnaire that has been designed for this study and distributed to the music students, I have expected to obtain a result that allow me to come to the conclusion that exists a relation between the hours of practice and the expertise in the execution. This reality has been linked to the regarding situation in the sport practice, whose information has been provided by the coordinators of the different sports. Taking into account the limited number of references available, this work has focused on a qualitative analysis of the data, interpreted from my point of view and my personal experience, which has been confirmed in the results obtained. The statistics managed allow me to conclude that, although the argument is not definitive, the guide effort through deliberate practice is essential to achieve the excellence.

Membrane activities of Dynamin-related protein 1 (DRP1) and BCL2-related Ovarian Killer (BOK)

311 p.