Physico-chemical interactions between compartment-forming lipids and other prebiotically relevant biomolecules

Lipids are essential constituents of contemporary living cells, serving as structural molecules that are necessary to form membranous compartments. Amphiphilic lipid-like molecules may also have contributed to prebiotic chemical evolution by promoting the synthesis, aggregation and cooperative encapsulation of other biomolecules. The resulting compartments would allow systems of molecules to be maintained that represent microscopic experiments in a natural version of combinatorial chemistry. Here we address these possibilities and describe recent results related to interactions between amphiphiles and other biomolecules during early evolution toward the first living cells.

Design, physico-chemical characterization and bioactivity studies of hybrid nanostructured titanium surfaces for enhanced osseointegration

170 p.

Effect of the A cation size disorder and synthesis conditions on the properties of an iron perovskite series

Póster presentado en The Energy and Materials Research Conference - EMR2015 celebrado en Madrid (España) entre el 25-27 de febrero de 2015

Ionic Liquids and Cellulose: Dissolution, Chemical Modification and Preparation of New Cellulosic Materials

Due to its abundance and a wide range of beneficial physical and chemical properties, cellulose has become very popular in order to produce materials for various applications. This review summarizes the recent advances in the development of new cellulose materials and technologies using ionic liquids. Dissolution of cellulose in ionic liquids has been used to develop new processing technologies, cellulose functionalization methods and new cellulose materials including blends, composites, fibers and ion gels.

Human Papillomavirus (HPV) genotype 18 variants in patients with clinical manifestations of HPV related infections in Bilbao, Spain

Background:Human papillomavirus (HPV) variants differ in their biological and chemical properties, and therefore, may present differences in pathogenicity. Most authors classified variants based on the phylogenetic analysis of L1 region. Nevertheless, recombination in HPV samples is becoming a usual finding and thus, characterizing genetic variability in other regions should be essential. Objectives:We aimed to characterize the genetic variability of HPV 18 in 5 genomic regions: E6, E7, E4, L1 and the Upstream Regulatory Region (URR), working with both single infection and multiple HPV infection samples. Furthermore, we aimed to assess the prevalence of HPV 18 variants in our region and look for possible existence of recombination as well as analyze the relationship between these variants and the type of lesion. Methods: From 2007 to 2010, Clinical Microbiology and Infection Control Department analyzed 44 samples which were positive for HPV 18. Genetic variability was determined in PCR products and variants were assigned to European, Asian-amerindian or African lineage. Recombination and association of variants with different types of lesion was studied. Results: Genetic analysis of the regions revealed a total of 56 nucleotide variations. European, African and Asian-amerindian variants were found in 25/44 (56.8%), 10/44 (22.7%) and 5/44 (11.4%) samples, respectively. We detected the presence of recombinant variants in 2/44 (4.5%) cases. Samples taken from high-grade squamous intraepithelial lesions (H-SIL) only presented variants with specific-african substitutions. Conclusions: Multiple HPV infection, non-european HPV variants prevalence and existence of recombination are considered risk factors for HPV persistence and progression of intraepithelial abnormalities, and therefore, should be taken into consideration in order to help to design and optimize diagnostics protocols as well as improve epidemiologic studies. Our study is one of the few studies in Spain which analyses the genetic variability of HPV18 and we showed the importance of characterizing more than one genomic region in order to detect recombination and classify HPV variants properly

Análisis de la fabricación de las tijas de una motocicleta de competición. Prototipo

[ES]Este trabajo fin de grado, TFG en adelante, consiste en el análisis de la fabricación de las tijas de una motocicleta de competición Motostudent. Se trata de conseguir fabricar las tijas de una manera óptima, tanto en que su material como el proceso de fabricación sea el más adecuado para su función siendo, además, lo más económico posible. Para llevar a cabo este trabajo es necesario conocer las cualidades que una tija debe cubrir en una motocicleta de competición. A partir de dichas cualidades se selecciona el material idóneo de entre otros muchos, estudiando las propiedades fiscas, químicas y mecánicas de cada uno de ellos. También se hará un estudio de dos alternativas de fabricación posibles, electroerosión y arranque de viruta con herramienta, para a posteriori elegir la más indicada. La idea no es construir un diseño final para la fabricación, sino un prototipo sobre el cual hacer las pruebas oportunas y posteriormente realizar cambios y mejoras para posteriores ediciones. El presente proyecto marcará las pautas de diseño y el proceso a seguir durante la fabricación de las tijas que el equipo representante de la Escuela técnica superior de Bilbao, ETSIB en adelante, empleará en la futura competición.

En torno al llamado «arte esquemático-abstracto»: a propósito de unas fechas de Covalanas (Ramales de la Victoria, Cantabria)

[ES] La introducción de técnicas físico-químicas al estudio del grafismo rupestre paleolítico está abriendo nuevos campos de conocimiento sobre los procedimientos técnicos, la cronología y la conservación de los motivos. La utilización de la técnica radiométrica de C14 A.M.S. ha sido aplicada en Covalanas. Las dataciones de época histórica de dos pequeños fragmentos de carbón procedentes de marcas negras sirven para reflexionar en torno al llamado «arte esquemático-abstracto».

Composite beta-AgVO3@V5+1.6V4+0.4O4.8 hydrogels and xerogels for catalytic applications

Comunicación (Poster) en panel del congreso: Designing New Heterogeneous Catalysts, Faraday Discussion, 4–6 April 2016. London, United Kingdom.

Fluidic flow delay by ionogel passive pumps in microfluidicpaper-based analytical devices

[EN] A new concept for fluid flow manipulation in microfluidic paper-based analytical devices ( µPADs) is presented by introducing ionogel materials as passive pumps. µPADs were fabricated using a new doubleside contact stamping process and ionogels were precisely photopolymerised at the inlet of the µPADs.The ionogels remain mainly on the surface of the paper and get absorbed in the superficial paper-fibers allowing for the liquid to flow from the ionogel into the paper easily. As a proof of concept the fluid flow and mixing behaviour of two different ionogels µPADs were compared with the non-treated µPADs.It was demonstrated that both ionogels highly affect the fluid flow by delaying the flow due to their different physical and chemical properties and water holding capacities.