Geometric documentation and reconstruction of the church of the Monastery of San Prudencio (La Rioja, Spain)

[EN] Data contained in this record come from the following accademic activity (from which it is possible to locate additional records related with the Monastery):

The Loss of Functional Caspase-12 in Europe Is a Pre-Neolithic Event

6 p.

Kv7 Channels Can Function without Constitutive Calmodulin Tethering

9 p.

Producci??n cient??fica de la Praxiolog??a Motriz en el siglo XXI

se ha realizado una producci??n cient??fica de la Praxiolog??a Motriz en el siglo XXI, a partir de los art??culos, libros, tesis, congresos y seminarios de ocho autores referencia, tanto a nivel estatal como mundial dentro de este ??mbito. El objetivo de esta producci??n cient??fica es determinar si todo lo que se ha recopilado y clasificado sobre estos autores pertenece al ??mbito de la Praxiolog??a motriz. La b??squeda de art??culos se ha realizado principalmente, mediante la base de datos Dialnet, mientras que la herramienta para la clasificaci??n y el dise??o de las tablas y cuadros se ha realizado con el sistema inform??tico Microsoft Excel??. Durante este periodo se han publicado un total de 60 art??culos cient??ficos, con un promedio de 7.5 art??culos por autor, cuatro art??culos al a??o y a raz??n de 8.5 art??culos por apartado. Estos datos indican que la producci??n cient??fica es pobre ya que tan solo tres autores son los que centran la mayor??a de publicaciones y tres los apartados con la mayor??a de textos. Se ha enfatizado la necesidad de tener facilidad para una informaci??n mayor sobre art??culos, seminarios y congresos para tener mayor volumen de art??culos dado que 43 son los art??culos que se han quedado sin clasificar.

Goi mailako errugbi talde batean aurredenboraldiaren efektuak zineantropometria, gorputz osaera eta somatotipoan

Ikerketa lan honen helburu nagusia, Espainiako maila gorenean jokatzen aritzen den Getxo Errugbi taldeko jokalarien estruktura biotipologikoa eta somatotipoa aztertzea eta aurre-denboraldian zehar, hau da, 10 astetan zehar gorputz egituran jasandako aldaketak baloratzea izan da. Bestalde, aurrelarien eta atzelarien arteko desberdintasunak eta postuaren arabera aurre-denboraldiak duen eragina sumatzearen helburua ere izan du ikerketa honek. Horretarako, aurre-denboraldiaren hasieran, ekainaren 18an eta amaieran, abuztuaren 27an, elite mailako diren 30 jokalariren datu antropometrikoak neurtu izan ziren. Datu antropometrikoak altuera, pisua, larruazaleko tolesturak, hezur diametroak eta gorputz adarren perimetroak izan ziren. 30 jokalarien ekaineko batez besteko adina, esperientzia, altuera, pisua, gorputz masa indizea eta gantz ehunekoa hurrengokoak izan ziren hurrenez hurren; 25,7 ?? 5,7 urte, 14,3 ?? 6,1 urte, 181,5 ?? 6,8 cm, 91,2 ?? 17,7 kg, 27,6 ?? 4,6 GMI eta 13,48 ?? 3,66 gantz %. Metodologiari dagokionez, kirolari bakoitzaren somatotipoa Heath-Carter metodoaren bidez kalkulatua izan da eta gantz ehunekoa eta gantz masa 4 gunetako Jackson/Pollock gantz kalibre metodoaren bidez kalkulatu izan dira.

El efecto de la acidificación de los océanos sobre microalgas de la división chlorophyta

Se cultivaron tres cepas de la división Chlorophyta (Nephroselmis pyriformis cepa CGA7, Pyramimonas orientalis cepa CGA13 y Pyramimonas propulsa cepa CGA16) en medios a cuatro pH diferentes (rango desde un control a pH 8.1 a pH7.2). Se midieron las tasas de crecimiento para cada cepa y tratamiento. Las cepas no mostraron una respuesta uniforme a la acidificación del medio, aunque todas mostraron un incremento de sus tasas de crecimiento a pH 7.5. Únicamente N. pyriformis mostró un incremento de sus tasas de crecimiento a pH 7.2. Se concluye que la división Chlorophyta no muestra una respuesta uniforme a la acidificación del medio, pero que las tasas de crecimiento pueden verse incrementadas para las especies testadas en futuros escenarios de acidificación de los océanos.

Cerebral hemodynamics during graded Valsalva maneuvers

The Valsalva maneuver (VM) produces large and abrupt changes in mean arterial pressure (MAP) that challenge cerebral blood flow and oxygenation. We examined the effect of VM intensity on middle cerebral artery blood velocity (MCAv) and cortical oxygenation responses during (phases I-III) and following (phase IV) a VM. Healthy participants (n = 20 mean +/- SD: 27 +/- 7 years) completed 30 and 90% of their maximal VM mouth pressure for 10 s (order randomized) whilst standing. Beat-to-beat MCAv, cerebral oxygenation (NIRS) and MAP across the different phases of the VM are reported as the difference from standing baseline. There were significant interaction (phase * intensity) effects for MCAv, total oxygenation index (TOI) and MAP (all P < 0.01). MCAv decreased during phases II and III (P < 0.01), with the greatest decrease during phase III (-5 +/- 8 and -19 +/- 15 cm.s(-1) for 30 and 90% VM, respectively). This pattern was also evident in TOI (phase III: -1 +/- 1 and -5 +/- 4%, both P < 0.05). Phase IV increased MCAv (22 +/- 15 and 34 +/- 23 cm.s(-1)), MAP (15 +/- 14 and 24 +/- 17 mm Hg) and TOI (5 +/- 6 and 7 +/- 5%) relative to baseline (all P < 0.05). Cerebral autoregulation, indexed, as the % MCAv/%MAP ratio, showed a phase effect only (P < 0.001), with the least regulation during phase IV (2.4 +/- 3.0 and 3.2 +/- 2.9). These data illustrate that an intense VM profoundly affects cerebral hemodynamics, with a reactive hyperemia occurring during phase IV following modest ischemia during phases II and III.

Valuation of Wind Energy Projects: A Real Options Approach

We address the valuation of an operating wind farm and the finite-lived option to invest in it under different reward/support schemes: a constant feed-in tariff, a premium on top of the electricity market price (either a fixed premium or a variable subsidy such as a renewable obligation certificate or ROC), and a transitory subsidy, among others. Futures contracts on electricity with ever longer maturities enable market-based valuations to be undertaken. The model considers up to three sources of uncertainty: the electricity price, the level of wind generation, and the certificate (ROC) price where appropriate. When analytical solutions are lacking, we resort to a trinomial lattice combined with Monte Carlo simulation; we also use a two-dimensional binomial lattice when uncertainty in the ROC price is considered. Our data set refers to the UK. The numerical results show the impact of several factors involved in the decision to invest: the subsidy per MWh generated, the initial lump-sum subsidy, the maturity of the investment option, and electricity price volatility. Different combinations of variables can help bring forward investments in wind generation. One-off policies, e.g., a transitory initial subsidy, seem to have a stronger effect than a fixed premium per MWh produced.

Sphingomyelinase D/Ceramide 1-Phosphate in Cell Survival and Inflammation

Sphingolipids are major constituents of biological membranes of eukaryotic cells. Many studies have shown that sphingomyelin (SM) is a major phospholipid in cell bilayers and is mainly localized to the plasma membrane of cells, where it serves both as a building block for cell architecture and as a precursor of bioactive sphingolipids. In particular, upregulation of (C-type) sphingomyelinases will produce ceramide, which regulates many physiological functions including apoptosis, senescence, or cell differentiation. Interestingly, the venom of some arthropodes including spiders of the genus Loxosceles, or the toxins of some bacteria such as Corynebacterium tuberculosis, or Vibrio damsela possess high levels of D-type sphingomyelinase (SMase D). This enzyme catalyzes the hydrolysis of SM to yield ceramide 1-phosphate (C1P), which promotes cell growth and survival and is a potent pro-inflammatory agent in different cell types. In particular, C1P stimulates cytosolic phospholipase A2 leading to arachidonic acid release and the subsequent formation of eicosanoids, actions that are all associated to the promotion of inflammation. In addition, C1P potently stimulates macrophage migration, which has also been associated to inflammatory responses. Interestingly, this action required the interaction of C1P with a specific plasma membrane receptor, whereas accumulation of intracellular C1P failed to stimulate chemotaxis. The C1P receptor is coupled to Gi proteins and activates of the PI3K/Akt and MEK/ERK1-2 pathways upon ligation with C1P. The proposed review will address novel aspects on the control of inflammatory responses by C1P and will highlight the molecular mechanisms whereby C1P exerts these actions.