Nota biográfica sobre el General Mariano Gamir Ulibarri, Jefe del Cuerpo de Ejército Vasco entre mayo y agosto de 1937. La acompaña una nota biográfica sobre el libro "Relatos y reflexiones de la Guerra de España", obra de Francisco Ciutat, antiguo Jefe de Estado Mayor del Ejército del Norte de la República.

Fecha: >1970 / Unidad de instalación: Carpeta 48 - Expediente 7-2 / Nº de pág.: 2 (1 mecanografiada, 1 manuscrita)

Number of prior episodes and the presence of depressive symptoms are associated with longer length of stay for patients with acute manic episodes

Background: Few studies have analyzed predictors of length of stay (LOS) in patients admitted due to acute bipolar manic episodes. The purpose of the present study was to estimate LOS and to determine the potential sociodemographic and clinical risk factors associated with a longer hospitalization. Such information could be useful to identify those patients at high risk for long LOS and to allocate them to special treatments, with the aim of optimizing their hospital management. Methods: This was a cross-sectional study recruiting adult patients with a diagnosis of bipolar disorder (Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision (DSM-IV-TR) criteria) who had been hospitalized due to an acute manic episode with a Young Mania Rating Scale total score greater than 20. Bivariate correlational and multiple linear regression analyses were performed to identify independent predictors of LOS. Results: A total of 235 patients from 44 centers were included in the study. The only factors that were significantly associated to LOS in the regression model were the number of previous episodes and the Montgomery-Åsberg Depression Rating Scale (MADRS) total score at admission (P < 0.05). Conclusions: Patients with a high number of previous episodes and those with depressive symptoms during mania are more likely to stay longer in hospital. Patients with severe depressive symptoms may have a more severe or treatment-resistant course of the acute bipolar manic episode.

Un episodio de “estilización” de la política antirrepublicana: la fiesta de San Francisco Javier de 1931 en Pamplona

[ES] Estudio de caso (Fiesta de S. Francisco en Pamplona, Navarra) del modo en que la derecha conservadora española (Bloque de Derechas) y los radicales (carlistas) emplearon densos elementos identificadores (“identidad”) de lo local (Navarra-España) y católica para generar actitudes y adhesiones políticas antirrepublicanas.

Comercio y Colonias (1770-1850). El papel de Guipúzcoa

Hablar del papel de las colonias y del comercio en los siglos XVIII y XIX del País Vasco es un ciclo sobre Dirección y Administracion de empresas parece un tanto fuera de lugar. Problamenente muchos alumnos y sectores del profesorado no suelen tener muy claro para qué sirve una materia como la historia y más en concreto la historia económica. Sin embargo la Historia en general y la económia en particular cumplen o mejor, deberían cumplir un papel importante y sobre todo deberían ser tenidas en cuenta a la hora de tomar decisiones tanto a nivel micoeconómico como macroeconómico.

Radiotherapy plus nimotuzumab or placebo in the treatment of high grade glioma patients: results from a randomized, double blind trial

Background The prognosis of patients bearing high grade glioma remains dismal. Epidermal Growth Factor Receptor (EGFR) is well validated as a primary contributor of glioma initiation and progression. Nimotuzumab is a humanized monoclonal antibody that recognizes the EGFR extracellular domain and reaches Central Nervous System tumors, in nonclinical and clinical setting. While it has similar activity when compared to other anti-EGFR antibodies, it does not induce skin toxicity or hypomagnesemia. Methods A randomized, double blind, multicentric clinical trial was conducted in high grade glioma patients (41 anaplastic astrocytoma and 29 glioblastoma multiforme) that received radiotherapy plus nimotuzumab or placebo. Treatment and placebo groups were well-balanced for the most important prognostic variables. Patients received 6 weekly doses of 200 mg nimotuzumab or placebo together with irradiation as induction therapy. Maintenance treatment was given for 1 year with subsequent doses administered every 3 weeks. The objectives of this study were to assess the comparative overall survival, progression free survival, response rate, immunogenicity and safety. Results The median cumulative dose was 3200 mg of nimotuzumab given over a median number of 16 doses. The combination of nimotuzumab and RT was well-tolerated. The most prevalent related adverse reactions included nausea, fever, tremors, anorexia and hepatic test alteration. No anti-idiotypic response was detected, confirming the antibody low immunogenicity. The mean and median survival time for subjects treated with nimotuzumab was 31.06 and 17.76 vs. 21.07 and 12.63 months for the control group. Conclusions In this randomized trial, nimotuzumab showed an excellent safety profile and significant survival benefit in combination with irradiation.

Validation of a Spanish version of the Revised Fibromyalgia Impact Questionnaire (FIQR)

8 p.

Cartas enviadas por Francisco de Abrisqueta a Justo Garate entre 1968 y 1973

8 cartas y 3 tarjetas (mecanografiadas y manuscritas) ; entre 220x280mm y 190x74mm. Ubicación: Caja 1 - Carpeta 2

Impact of depressive symptoms on subjective well-being: the importance of patient-reported outcomes in schizophrenia

Objective: The subjective experience of psychotic patients toward treatment is a key factor in medication adherence, quality of life, and clinical outcome. The aim of this study was to assess the subjective well-being in patients with schizophrenia and to examine its relationship with the presence and severity of depressive symptoms. Methods: A multicenter, cross-sectional study was conducted with clinically stable outpatients diagnosed with schizophrenia. The Subjective Well-Being under Neuroleptic Scale - short version (SWN-K) and the Calgary Depression Scale for Schizophrenia (CDSS) were used to gather information on well-being and the presence and severity of depressive symptoms, respectively. Spearman's rank correlation was used to assess the associations between the SWN-K total score, its five subscales, and the CDSS total score. Discriminative validity was evaluated against that criterion by analysing the area under the curve (AUC). Results: Ninety-seven patients were included in the study. Mean age was 35 years (standard deviation = 10) and 72% were male. Both the total SWN-K scale and its five subscales correlated inversely and significantly with the CDSS total score (P < 0.0001). The highest correlation was observed for the total SWN-K (Spearman's rank order correlation [ rho] = -0.59), being the other correlations: mental functioning (-0.47), social integration (-0.46), emotional regulation (-0.51), physical functioning (-0.48), and self-control (-0.41). A total of 33 patients (34%) were classified as depressed. Total SWN-K showed the highest AUC when discriminating between depressive severity levels (0.84), followed by emotional regulation (0.80), social integration (0.78), physical functioning and self-control (0.77), and mental functioning (0.73). Total SWN-K and its five subscales showed a significant linear trend against CDSS severity levels (P < 0.001). Conclusion: The presence of moderate to severe depressive symptoms was relatively high, and correlated inversely with patients' subjective well-being. Routine assessment of patient-reported measures in patients with schizophrenia might reduce potential discrepancy between patient and physician assessment, increase therapeutic alliance, and improve outcome.

Cartas enviadas por Francisco Apalategui a Justo Garate entre 1930 y 1931

1 tarjeta y 1 carta (manuscritas y mecanografiadas) ; entre 146x92mm y 135x215mm. Ubicación: Caja 1 - Carpeta 31

Cartas enviadas por Francisco R. de Arbulu a Justo Garate en 1970

12 cartas y 2 notas (manuscritas) ; entre 160x215mm y 240x350mm. Ubicación: Caja 1 - Carpeta 41

Cartas enviadas por Francisco R. de Arbulu a Justo Garate entre 1972 y 1973

12 cartas (manuscritas) ; entre 215x230mm y 210x2970mm. Ubicación: Caja 1 - Carpeta 41

Cartas enviadas por Francisco de Belausteguigoitia a Justo Garate entre 1925 y 1952

8 cartas (manuscritas y mecanografiadas) ; entre 315x200mm y 155x183mm .- 1 Tarjeta de Navidad (manuscrita) ; 100x280mm.- 1 Invitación de boda (mecanografiada) ; 170x110mm.

San Francisco : a city reinvented by creative innovation

The aim of this paper is to analyse the recent evolution of the city of San Francisco to outline the major features that have made it possible this continuing process of creative innovation in the city. In order to meet this objective, the project is framed around answering two key research questions: (1) what are the main economic and social elements that characterise urban change in the city of San Francisco and (2) which is the role of public strategies in the continuing economic success of San Francisco. The paper concludes that the successful performance of San Francisco is the result of the actions taken by many agents in the city, but the role of public authorities, especially the City and County, must be stressed, both through direct intervention and by coordinating, fostering and supporting the private and non-profit sectors. This is especially relevant in a country like the US where private initiative has been seen in many occasions as the greatest driver of economic and social success. Yet, the performance of San Francisco City cannot be explained without the role played by the public sector, in coordination with the civil society

Cartas enviadas por Francisco de Belausteguigoitia a Justo Garate entre 1953 y 1976

10 cartas (mecanografiadas) ; entre 215x275mm y 215x140mm

Cartas enviadas por Francisco de Belausteguigoitia a Justo Garate entre 1977 y 1980

8 cartas (mecanografiadas) ; entre 210x300mm y 215x140mm.- 1 carta de Justo Garate a Belausteguigoitia en 1968 (mecanografiada) ; 225x175mm.- 1 esquela de la viuda de Belausteguigoitia ; 120x70mm