13 resultados para Alonso, Carlos

em Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco


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Fecha: 20-4-1943 (>1970 reproducción) / Unidad de instalación: Carpeta 25 - Expediente 23-3 / Nº de pág.: 1 (mecanografiada)

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[ES] La internacionalización de la producción de las factorías navales viene impulsada por las posibilidades que las nuevas técnicas de construcción abren a la desagregación de los procesos productivos. Además, los avances experimentados en las tecnologías de la información y comunicación reducen los inconvenientes de la deslocalización de actividades en distintos centros ubicados en áreas geográficas distantes. Asimismo, el abaratamiento de los costes de transporte resta importancia a los escollos del desplazamiento de las partes del buque entre los distintos puntos de construcción. Pese a ello, en el sector naval, cuyo mercado objetivo habitual es de ámbito mundial, la internacionalización de la producción resulta ser una práctica menos frecuente.

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[ES] A partir de los microdatos de la "encuesta sobre innovación tecnológica 1998-2000" se construye una base de datos con las empresas manufactureras españolas que realizan actividades de innovación. Posteriormente, mediante las pruebas Chi-cuadrado de Pearson y Mann-Whitney, contrastamos si el tamaño condiciona la participación de las empresas manufactureras innovadoras en los sistemas de ayuda pública a la innovación; asimismo, a través de los índices de Kendall y Spearman evaluamos la dirección de dicho condicionamiento. Al respecto, los contrastes realizados nos indican que la variable tamaño se encuentra relacionada con la variable financiación pública, y que son las empresas de mayor tamaño las que más se benefician de las ayudas públicas a la innovación.

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Eguíluz, Federico; Merino, Raquel; Olsen, Vickie; Pajares, Eterio; Santamaría, José Miguel (eds.)

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A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.

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The work presented here is part of a larger study to identify novel technologies and biomarkers for early Alzheimer disease (AD) detection and it focuses on evaluating the suitability of a new approach for early AD diagnosis by non-invasive methods. The purpose is to examine in a pilot study the potential of applying intelligent algorithms to speech features obtained from suspected patients in order to contribute to the improvement of diagnosis of AD and its degree of severity. In this sense, Artificial Neural Networks (ANN) have been used for the automatic classification of the two classes (AD and control subjects). Two human issues have been analyzed for feature selection: Spontaneous Speech and Emotional Response. Not only linear features but also non-linear ones, such as Fractal Dimension, have been explored. The approach is non invasive, low cost and without any side effects. Obtained experimental results were very satisfactory and promising for early diagnosis and classification of AD patients.

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Antonio Duplá Ansuátegui, Piedad Frías Nogales e Iban Zaldúa (editores)

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2 caras (manuscritas) ; 215x145mm. Ubicación: Caja 1 - Carpeta 22

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This paper describes Mateda-2.0, a MATLAB package for estimation of distribution algorithms (EDAs). This package can be used to solve single and multi-objective discrete and continuous optimization problems using EDAs based on undirected and directed probabilistic graphical models. The implementation contains several methods commonly employed by EDAs. It is also conceived as an open package to allow users to incorporate different combinations of selection, learning, sampling, and local search procedures. Additionally, it includes methods to extract, process and visualize the structures learned by the probabilistic models. This way, it can unveil previously unknown information about the optimization problem domain. Mateda-2.0 also incorporates a module for creating and validating function models based on the probabilistic models learned by EDAs.

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Homenaje a Georges Laplace, realizado en Vitoria-Gasteiz el 13,14 y 15 de noviembre de 2012. Edición a cargo de Aitor Calvo, Aitor Sánchez, Maite García-Rojas y Mónica Alonso-Eguíluz.

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We aimed to study the selective pressures interacting on SLC45A2 to investigate the interplay between selection and susceptibility to disease. Thus, we enrolled 500 volunteers from a geographically limited population (Basques from the North of Spain) and by resequencing the whole coding region and intron 5 of the 34 most and the 34 least pigmented individuals according to the reflectance distribution, we observed that the polymorphism Leu374Phe (L374F, rs16891982) was statistically associated with skin color variability within this sample. In particular, allele 374F was significantly more frequent among the individuals with lighter skin. Further genotyping an independent set of 558 individuals of a geographically wider population with known ancestry in the Spanish population also revealed that the frequency of L374F was significantly correlated with the incident UV radiation intensity. Selection tests suggest that allele 374F is being positively selected in South Europeans, thus indicating that depigmentation is an adaptive process. Interestingly, by genotyping 119 melanoma samples, we show that this variant is also associated with an increased susceptibility to melanoma in our populations. The ultimate driving force for this adaptation is unknown, but it is compatible with the vitamin D hypothesis. This shows that molecular evolution analysis can be used as a useful technology to predict phenotypic and biomedical consequences in humans.

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El TFG versa sobre los cambios histórico-legales que se dieron en los siglos XVIII y XIX en relación con los derechos forales de los Territorios Históricos vascos y su configuración hasta 1876, momento en que se derogan para volver a ser puestos en curso con la llegada de la Constitución Española de 1978 y todo lo que ello significó para la vida y el derecho de los vecinos del Señorio de Vizcaya.