Nazioarteko ekonomia eta nazioarteko erakundeak

Azken hamarkadan eredu liberalaren hedapenak eraginda nazioarteko akordioak, gehienbat eskualde mailakoak, ugaritu egin dira. Horrek, ekonomia arloan, merkataritza eta inbertsioak gai nagusi bihurtu ditu. Nazioarteko mailan harreman ekonomikoak zehaztasunez aztertzera bultzatzen gaitu. Nazioarteko harreman hauetan aipatzekoak dira potentzia ekonomiko maila ezberdinen arteko elkartrukeak. Hala nola periferia-zentro edota ipar-hegoaldeen arteko merkataritza erlazioa, AEB eta Mexikoren NAFTA merkataritza librerako ituna adibide dena.

Nazioarteko merkataritza akordioak

Euskaraz idatzita.Amerikako Estatu Batuen eta Erdialdeko Amerikaren arteko harremanak aztertzen dira bertan, DR-CAFTA izeneko Merkataritza Libreko Akordioak, epe labur, ertain eta luzean Erdialdeko Amerikako Herialdeentzat suposatu dituen ondorio garrantzitsuenak azaltzen dira bertan.

RESTful Discovery and Eventing for Service Provisioning in Assisted Living Environments

Service provisioning in assisted living environments faces distinct challenges due to the heterogeneity of networks, access technology, and sensing/actuation devices in such an environment. Existing solutions, such as SOAP-based web services, can interconnect heterogeneous devices and services, and can be published, discovered and invoked dynamically. However, it is considered heavier than what is required in the smart environment-like context and hence suffers from performance degradation. Alternatively, REpresentational State Transfer (REST) has gained much attention from the community and is considered as a lighter and cleaner technology compared to the SOAP-based web services. Since it is simple to publish and use a RESTful web service, more and more service providers are moving toward REST-based solutions, which promote a resource-centric conceptualization as opposed to a service-centric conceptualization. Despite such benefits of REST, the dynamic discovery and eventing of RESTful services are yet considered a major hurdle to utilization of the full potential of REST-based approaches. In this paper, we address this issue, by providing a RESTful discovery and eventing specification and demonstrate it in an assisted living healthcare scenario. We envisage that through this approach, the service provisioning in ambient assisted living or other smart environment settings will be more efficient, timely, and less resource-intensive.

Osasun politikak garapenerako lankidetzan: Milaurteko Helburuak eta azken joerak

Garapena lortzeko Milaurteko Akordioa sinatu zenetik gaur egun arte eman diren aldaketen analisi sakon bat egin, helburuen nondik norako jarraipen bat eginez eta errealitatea zorrotz aztertuz. Hizkuntza: Euskera.

Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma

Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic traits. Several low penetrance susceptibility genes associated with malignant melanoma (MM) have been described, including genes related to pigmentation, DNA damage repair and oxidative stress pathways. In the present work, we conducted a candidate gene association study based on proteins and genes whose expression we had detected altered in melanoma cell lines as compared to normal melanocytes. The result was the selection of 88 loci and 384 SNPs, of which 314 fulfilled our quality criteria for a case-control association study. The SNP rs6854854 in ANXA5 was statistically significant after conservative Bonferroni correction when 464 melanoma patients and 400 controls were analyzed in a discovery Phase I. However, this finding could not be replicated in the validation phase, perhaps because the minor allele frequency of SNP rs6854854 varies depending on the geographical region considered. Additionally, a second SNP (rs6431588) located on ILKAP was found to be associated with melanoma after considering a combined set of 1,883 MM cases and 1,358 disease-free controls. The OR was 1.29 (95% CI 1.12-1.48; p-value= 4x10(-4)). Both SNPs, rs6854854 in ANXA5 and rs6431588 in ILKAP, show population structure, which, assuming that the Spanish population is not significantly structured, suggests a role of these loci on a specific genetic adaptation to different environmental conditions. Furthermore, the biological relevance of these genes in MM is supported by in vitro experiments, which show a decrease in the transcription levels of ANXA5 and ILKAP in melanoma cells compared to normal melanocytes.

The patents in the introduction of reinforced concrete in Spain: "Alhondiga de Bilbao" case study

Reinforced concrete structures are introduced in Spain mainly by French influence. This happens in the late nineteenth century, following the scheme operating through proprietary systems prevailing in Europe. Systems initially have poor scientific support reaching, even early twentieth century, an impediment to the development of concrete structures, due to the lack of knowledge shown, as well as due to a series of accidents. Therefore, from the end of the first decade of the past century are enacted a series of regulations in many countries, that will change the design and calculation of reinforced concrete structure. The knowledge of the environment of the patent systems, its beginnings and the circumstances of their application allow us to understand the constraints of the early concrete structures, as presented in the Bilbao wine store (1906).

La implantación de un sistema de costes en una empresa vitivinícola: análisis comparativo entre los costes históricos y el valor razonable

En este trabajo se expone el valor razonable como criterio alternativo al coste histórico con el fin de actualizar todos los costes valorados a coste histórico, ya que el poder adquisitivo de la moneda varía de un año a otro. Esto implica actualizar los inmovilizados y las existencias de productos en curso teniendo en cuenta los valores del mercado, las tasaciones de peritos y los índices de precios (IPC) con el fin de que los activos de la empresa no se infravaloren y la variación de precios no afecte a los resultados ni al coste del producto, y así la información que suministra la contabilidad de costes sea relevante para la toma de decisiones.

Mausitxa gaztandegia

Gradu amaierako lan hau, Mausitxa gaztandegiari egindako aholkularitza lan bat da. Euskeraz egina dago.

Negozio Plana - Deskontu liburuxka

Gazteek, Donostian aisialdia gehiago eta merkeago gozatzeko aukerak eskaintzen dituen liburuxka eta weborria barneratzen dituen proiektua da.

On some new mathematical models for infective diseases: analysis, equilibrium, positivity and vaccination controls

196 p.

Uros, genética, indígenas y colonos. A propósito de la Neolitización de Europa

El presente trabajo se ha preparado en el seno de los intereses de los proyectos de investigación: HAR2011-26364 “Las Comunidades humanas de la alta Cuenca del Ebro en la Transición Pleistoceno-Holoceno” del Ministerio de Ciencia e Innovación y CGL2009-12703-C03-03 “Geología, geocronología y paleobiología de los Yacimientos de la Sierra de Atapuerca” del Ministerio de Educación y Ciencia. Así mismo se encuadra en el trabajo del Grupo de Investigación en Prehistoria de la Universidad del País Vasco (UPV/EHU) IT-288-07/ UFI 11-09.