27 resultados para capital natural.
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28 p.
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25 p.
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[ES]Diseño de una instalación de cogeneración basada en un motor de combustible gas natural para una empresa de tratamientos térmicos y superficiales. Para satisfacer las necesidades energéticas de la planta, la potencia eléctrica la suministrará un alternador conectado al motor y, a su vez, la entalpía de los humos de escape del motor se aprovechará para la producción de vapor de agua, necesario para la actividad industrial de la empresa. Por otro lado, el calor que es necesario disipar de dicho motor se recuperará para el calentamiento de agua de red, con la finalidad de limpiar la taladrina de las piezas tratadas.
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En los últimos años la financiación de empresas de nueva creación se ha convertido en uno de los principales obstáculos para los emprendedores a la hora de poner en marcha sus ideas de negocio. La difícil situación económico-financiera actual y las características particulares de estas empresas hacen que la financiación bancaria sea una alternativa más bien inviable. Este trabajo pretende explorar otras fuentes de financiación alternativas a la bancaria que se puedan ajustar más a las características de las empresas de reciente creación y, más en concreto, estudiar el papel que ha jugado y juega el venture capital como fuente de financiación, analizando aspectos teóricos del mismo y su evolución en los últimos años para, posteriormente, desarrollar un estudio empírico que analice las características y resultados obtenidos por las empresas financiadas por venture capital en España en los últimos años.
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IDOKI SCF Technologies S.L. is a technology-based company, set up on September 2006 in Derio (Biscay) with the main scope of developing extraction and purification processes based on the use of supercritical fluid extraction technology (SFE) in food processing, extraction of natural products and the production of personal care products. IDOKI¿s researchers have been working on many different R&D projects so far, most of them using this technology. However, the optimization of a SFE method for the different matrices cannot be performed unless we have an analytical method for the characterisation of the extracts obtained in each experiment. The analytical methods are also essential for the quality control of the raw materials that are going to be used and also for the final product. This PhD thesis was born to tackle this problem and therefore, it is based on the development of different analytical methods for the characterisation of the extracts and products. The projects that we could include in this thesis were the following: the extraction propolis, the recovery of agroindustrial residues (soy and wine) and the dealcoholisation of wine.On the one hand, for the extraction of propolis, several UV-Vis spectroscopic methods were used in order to measure the antioxidant capacity and the total polyphenol and flavonoid content of the extracts. A SFC method was also developed in order to measure more specific phenolic compounds. On the other hand, for the recovery of agroindustrial residues UV-Vis spectroscopy was used to determine the total polyphenol content and two SFC methods were developed to analyse different phenolic compounds. Extraction methods such as MAE, FUSE and rotary agitation were also evaluated for the characterisation of the raw materials.Finally, for the dealcoholisation of wine, the development of a SBSE-TD-GC-MS and DHS-TD-GC-MS methods for the analysis of aromas and a NIR spectroscopic method for the determination of ethanol content with the help of chemometrics was necessary. Most of these methods are typically used in IDOKI¿s lab as routine analyses apart from others not included in this PhD thesis.
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[EN] In today s economy, innovation is considered to be one of the main driving forces behind business competitiveness, if not the most relevant one. Traditionally, the study of innovation has been addressed from different perspectives. Recently, literature on knowledge management and intellectual capital has provided new insights. Considering this, the aim of this paper is to analyze the impact of different organizational conditions i.e. structural capital on innovation capability and innovation performance, from an intellectual capital (IC) perspective. As regards innovation capability, two dimensions are considered: new idea generation and innovation project management. The population subject to study is made up of technology-based Colombian firms. In order to gather information about the relevant variables involved in the research, a questionnaire was designed and addressed to the CEOs of the companies making up the target population. The sample analyzed is made up of 69 companies and is large enough to carry out a statistical study based on structural equation modelling (partial least squares approach) using PLS-Graph software (Chin and Frye, 2003). The results obtained show that structural capital explains to a great extent both the effectiveness of the new idea generation process and of innovation project management. However, the influence of each specific organizational component making up structural capital (organizational design, organizational culture, hiring and professional development policies, innovation strategy, technological capital, and external structure) varies. Moreover, successful innovation project management is the only innovation capability dimension that exerts a significant impact on company performance.
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328 p.
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We aimed to study the selective pressures interacting on SLC45A2 to investigate the interplay between selection and susceptibility to disease. Thus, we enrolled 500 volunteers from a geographically limited population (Basques from the North of Spain) and by resequencing the whole coding region and intron 5 of the 34 most and the 34 least pigmented individuals according to the reflectance distribution, we observed that the polymorphism Leu374Phe (L374F, rs16891982) was statistically associated with skin color variability within this sample. In particular, allele 374F was significantly more frequent among the individuals with lighter skin. Further genotyping an independent set of 558 individuals of a geographically wider population with known ancestry in the Spanish population also revealed that the frequency of L374F was significantly correlated with the incident UV radiation intensity. Selection tests suggest that allele 374F is being positively selected in South Europeans, thus indicating that depigmentation is an adaptive process. Interestingly, by genotyping 119 melanoma samples, we show that this variant is also associated with an increased susceptibility to melanoma in our populations. The ultimate driving force for this adaptation is unknown, but it is compatible with the vitamin D hypothesis. This shows that molecular evolution analysis can be used as a useful technology to predict phenotypic and biomedical consequences in humans.
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La idea del proyecto consiste en crear una asociación orientada a la gestión de actividades recreativo-deportivas en el medio natural. En un enclave puramente rural, la asociación tendrá su sede en Jaurrieta, un pueblo del Pirineo Navarro con menos de 200 habitantes. La intención es que el pueblo de Jaurrieta y el propio Valle de Salazar, formen parte de esta asociación, involucrando a un gran número de personas. Se considera que la unión y la heterogeneidad de cada una de estas personas, potenciarán positivamente la propuesta. Con el objetivo de ofrecer actividades recreativo-deportivas y servicios complementarios, se aprovecharán los recursos naturales del entorno para proporcionar al visitante un mayor conocimiento de la zona y su estilo de vida rural. La oferta de actividades recreativo-deportivas en el medio natural, estará dirigida a aquellas personas que decidan pasar su tiempo de ocio en el Pirineo Navarro. Por esto, surge la necesidad de elaborar un “Plan Estratégico” que facilite la creación y desarrollo de esta asociación. Como misión o fin último de la propuesta, se pretende contribuir en el desarrollo rural del Valle de Salazar; desde una perspectiva de progreso económico y social.
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[ES] Los recursos de naturaleza intangible se han convertido en los bienes más importantes que poseen las empresas para generar riqueza de manera sostenible, en concreto el Capital Humano. Sin embargo, el éxito y supervivencia de la empresa se encuentra sometida a la aprobación de sus grupos de interés (stakeholders). Por ello, las empresas deben adoptar medidas para garantizar que sus actuaciones sean percibidas por sus stakeholders como legítimas; una manera para legitimarse es mediante el suministro de información voluntaria. Por tanto, bajo el marco de la Teoría de la Legitimidad y de los Stakeholders, nuestro objetivo es analizar cómo las empresas españolas están informando de manera voluntaria sobre su Capital Humano en los informes anuales, desde una doble perspectiva informativa: la generación de intangibles (conocimiento) y la responsabilidad social. Así, usando la metodología del análisis de contenido, la evidencia empírica muestra que las empresas españolas suministran escasa información acerca de su Capital Humano, siendo los temas relacionados con la formación y el desarrollo de los empleados los más divulgados. No obstante, y con respecto a la responsabilidad social, hay que destacar la tendencia alcista por parte de las empresas a suministrar información relativa a la política de igualdad y diversidad, la prevención de riesgos laborales y las relaciones entre empleadores y empleados.
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[EN] Protein Kinase G (PKG) or cGMP-dependent protein kinases (PKG) have been shown to play an important role in resistance to abiotic stressors such as high temperatures or oxygen deprivation in Drosophila melanogaster. In Drosophila, the foraging gene encodes a PKG; natural variants for this gene exist, which differ in the level of expression of PKG: rovers (forR allele) which express high PKG levels, and sitters (forS allele) which express lower PKG levels. This project explores the differences in recovery from short periods of anoxia between natural variants (focusing on forS2, flies with a sitter gene in a rover background), as well as mutants with insertions in the foraging gene and RNAi recombinants that show a reduced PKG expression. The parameters measured were time to recovery and level of activity after anoxia. The results showed lower activity after anoxia in sitters than in rovers, reflecting a worse recovery from the anoxic coma in flies with lower PKG levels.