2 resultados para major histocompatibility complex
em Aquatic Commons
Resumo:
Major histocompatibility complex genes are thought to be involved in allogeneic graft rejection but not many reports are available on their functional analysis in fish. Analysis of available sequences of MHC genes suggests functions in antigen presentation similar to those found in higher vertebrates. In mammals, the MHC class I and class II molecules are major determinants of allogeneic graft rejection due to their polymorphism in conjunction with their antigen presenting function. In fish, MHC class H molecules are found to be involved in rejection of allogeneic scale grafts. The present study was designed to investigate the involvement of MHC class I molecules in allograft rejection. Erythrocytes were collected from donors of rainbow trout expressed different class MHC class I alleles, stained with two dyes, mixed and grafted to the recipients that were of the same sibling group as the donors. The grafts were rejected by allogeneic recipients and the MHC class I linkage group was the major determinant for the rejection.
Resumo:
The eastern Bering Sea is a major marine ecosystem containing some of the largest populations of groundfish, crabs, birds, and marine mammals in the world. Commercial catches of groundfish in this region have averaged about 1.6 million tons (t) annually in 1970-86. This report describes the species and relative importance of species in the eastern Bering Sea groundfish complex, the environment in which they live, and the history of the fisheries and management during the years 1954 - 1985. Historical changes in abundance and the condition of the principal species at the end of this first 30 years of exploitation are also examined. Results suggest that the biomass of the groundfish complex is characterized by variability rather than stability. The most reliable data (1979 to 1985) suggests that the biomass of the complex fluctuated between 11.8 and 15.7 million t. Even greater variability is suggested by the less reliable data from earlier years. Because of its dominance in the complex and wide fluctuations in abundance, walleye pollock (Theragra chalcogramma) is primarily responsible for the major variations in abundance of the complex. After 30 years of exploitation, the complex was generally in excellent condition. (PDF file contains 100 pages.)