2 resultados para Cartilage articulaire

em Aquatic Commons


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Marine by-products coming under the ancillary products group found many applications in pharmaceutical and industrial sectors. Although many of these products are fetching very high price at the export market, adequate statistics regarding their current production, marketing and utilisation is lacking. The present analysis deals with the production potential, level of exploitation, uses, export growth rate and potential for the future of some of these marine by-products. The analysis revealed that an estimated quantity of 205 t. of shells, 10 t. of gastropod operculum, 4,932 t. of shark liver oil and 4,384 t. of shark cartilage could be produced annually in India with the current landings. The production potential of chitin is estimated as 3,560 t. from shrimp shell wastes and 1,354 t. from crab shell wastes. The high unit value of different products clearly indicates the scope for their development by evolving appropriate utilisation and marketing strategies.

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The formation of the cartilage tissue depends on the coordination of cell to cell or cell to ECM interaction that cause to the cell polarity, migration and differentiation of precursor mesenchymal cells during chondrogenesis Many of these events are mediated by ECM components such as glycocojugates which with their suger residues such as galactose or aminosuger have a ligand role for regulatory molecules. The aim of this study was to identify the presence and distribution of some different glycoconjugates and their suger residues in the chondrogenesis by histochemistry and lectin-histochemistry techniques. For this purpose, embryos from pregnant wistar rats from E12-E20 were collected and fixed. Some of them were stained with alizarin red Salcin blue staining to demonstrate cartilage and bone formation in whole mount embryos. Other embryos with serial sections (5-7micm thikness) were stained by: 1-alcian blue (pH: l) for S-GAG,2-alcin blue (pH:2.5)for C-GAG, S-PAS alcian blue fora neutral and acidic sugers,4- tuloidin blue for metachromatic substances. Stained sections were graded according to the staining intensity (0-5 grading s method). Statistical analysis showed significant difference for those substances among experimental groups. Lectin histochemistry with MPA, VVA, SBA, OFA demonstrated differences between organs for suger residues during chondrogensis. It seems that synthesis and secretion of glycocojugates and change of their suger residues follows a spatiotemporal pattern and developmentaly regulated.