19 resultados para Biology, Cell|Health Sciences, Pharmacology|Chemistry, Biochemistry|Health Sciences, Oncology


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Transfers and introductions of marine species have occurred and are occurring on a worldwide basis, largely in response to perceived needs of expanding aquaculture industries. Greatest interest is in salmon (cage rearing and ocean ranching), shrimp, and bivalve mollusks, although other organisms are being considered. Such movements of animals carry an associated risk of moving pathogens into areas where they did not occur previously, possibly resulting in infections in native species. Many case histories of the effects of introduced pathogens and parasites now exist-enough to suggest that national and international action is necessary. Viral pathogens of shrimp and salmon, as well as protozoan parasites of mollusks and nematode parasites of eels, have entered complex "transfer networks" developed by humans, and have been transported globally with their hosts in several well-documented instances. Examining the records of transfers and introductions of marine species, incomplete as they are, permits the statement of emerging principles-foremost of which is that severe disease outbreaks can result from inadequately controlled or uncontrolled movements of marine animals.

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Prosiguiendo con la tarea de rescate de documentos realizada por ProBiota, tenemos el privilegio de editar en este número la obra A través de la Selva de Esteban Laureano Maradona. Hablar de esta figura, llamado por los indígenas Piognak que significa ‘Dr. Dios’ en pilagá, es mencionar a un ser humano generoso y solidario entregado totalmente al bien común. Un hombre que, además de su ejercicio profesional, se dedicó a la investigación cientifíca de la vida y cultura de los pueblos originarios, así como de la flora y fauna de la región ,colaborando con las comunidades locales en aspectos económicos, culturales, y sociales. No es nuestra intención realizar una sintesís de su vida ya que lo han realizado otros autores, pero si mencionar que, si bien recibió honores y reconocimientos en su larga vida, su figura no es conocida cabalmente en diversos niveles de la sociedad. Esto es una tarea que se debe llevar adelante desde diferentes frentes y una de las primeras sería,como menciona Wikipedia, la edición de algunos de sus 20 libros que se encuentran sin ser publicados, y esperan que el Congreso de la Nación Argentina cumpla con la resolución de 1994 de editarlos y donarlos a bibliotecas públicas del país, como fue el legado de su autor. Esperemos que los que tienen esta responsabilidad movilicen sus esfuerzos personales e institucionales para cumplir con el deseo de una persona que dio todo lo que podía dar sin esperar nada a cambio.

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Este documento reproduce parte de la magnífica e importante obra del P. Francisco José Sánchez Labrador realizada durante su estadía en América desde su arribo en 1734 hasta la expulsión de la orden en 1767. Esta versión digital corresponde al libro editado por la Compañía General Fabril Editora S. A. en 1968 y cuyo manuscrito fuera preparado bajo la dirección del Dr. Mariano N. Castex (imagen).

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In the present investigation the marine bacteria isolated from corals, sponges sea water and sediments of coral regions in the larak Island located in the Persian Gulf and were examined for ability to produce cytotoxic metabolits in order to use as an anticancer compounds. Cytotoxic effect were isolated bacteria from different samples and were examined by Artemia Cytotoxic Bioassay test, in which 4.5 percent of sea waters, 12 percent of sediments and 28 percent of marine invertebrat showed cytotoxic activity, using Brine Shrimp Bioassay test. Streptomyces S-2004 isolated from soft coral specified as Sinularia erecta had LC50=0.5mg/m1 in Brine Shrimp Bioaassay test. The streptomyces S-2004 produced cytotoxic metabolits in low nutrient condition and sea water medium after 7 days on 250 rpm shaken in vitro condition. The extract partially were semipurified. Then ethyl acetate extraction from aceton extracted of bacterial plate had cytotoxic effect (LC50=4.19ktg/m1) in Human epidermoid carcinoma of mouth cells (KB) by using neutral red assay. Morphological effects of this extract on KB cells showed turgescence, cellular blebs and apoptosis which was a proof for anticancer compounds of the extract. It is seems that streptomyces S-2004 is a new strain and could be introduced as a talented bacteria, which produced cytotoxic metabolits.