1 resultado para Justification of Principles of Justice
em National Center for Biotechnology Information - NCBI
Filtro por publicador
- Academic Archive On-line (Karlstad University; Sweden) (1)
- Academic Research Repository at Institute of Developing Economies (2)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (1)
- Aquatic Commons (1)
- Archive of European Integration (154)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (3)
- Aston University Research Archive (13)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (1)
- Biblioteca Digital de la Universidad Católica Argentina (1)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (2)
- Bibloteca do Senado Federal do Brasil (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (18)
- Boston College Law School, Boston College (BC), United States (3)
- Brock University, Canada (7)
- Bucknell University Digital Commons - Pensilvania - USA (3)
- Bulgarian Digital Mathematics Library at IMI-BAS (1)
- Cambridge University Engineering Department Publications Database (3)
- CentAUR: Central Archive University of Reading - UK (25)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (1)
- CiencIPCA - Instituto Politécnico do Cávado e do Ave, Portugal (1)
- Cochin University of Science & Technology (CUSAT), India (4)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (6)
- CORA - Cork Open Research Archive - University College Cork - Ireland (3)
- Corvinus Research Archive - The institutional repository for the Corvinus University of Budapest (4)
- Deakin Research Online - Australia (40)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (2)
- Digital Commons @ DU | University of Denver Research (2)
- Digital Commons at Florida International University (7)
- Digital Peer Publishing (5)
- DigitalCommons@The Texas Medical Center (3)
- DigitalCommons@University of Nebraska - Lincoln (1)
- Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland (1)
- DRUM (Digital Repository at the University of Maryland) (1)
- Duke University (2)
- Ecology and Society (1)
- Funes: Repositorio digital de documentos en Educación Matemática - Colombia (1)
- Harvard University (3)
- Helda - Digital Repository of University of Helsinki (5)
- Indian Institute of Science - Bangalore - Índia (1)
- Institute of Public Health in Ireland, Ireland (1)
- Institutional Repository of Leibniz University Hannover (1)
- Instituto Politécnico de Bragança (1)
- Instituto Superior de Psicologia Aplicada - Lisboa (1)
- Iowa Publications Online (IPO) - State Library, State of Iowa (Iowa), United States (1)
- Memoria Académica - FaHCE, UNLP - Argentina (3)
- Ministerio de Cultura, Spain (1)
- National Center for Biotechnology Information - NCBI (1)
- Portal de Revistas Científicas Complutenses - Espanha (2)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (56)
- Queensland University of Technology - ePrints Archive (339)
- RepoCLACAI - Consorcio Latinoamericano Contra el Aborto Inseguro (1)
- Repositorio Academico Digital UANL (1)
- Repositório Científico da Escola Superior de Enfermagem de Coimbra (1)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (1)
- Repositório digital da Fundação Getúlio Vargas - FGV (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (2)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (1)
- School of Medicine, Washington University, United States (2)
- Universidad de Alicante (1)
- Universidad del Rosario, Colombia (3)
- Universidad Politécnica de Madrid (7)
- Universidade Federal do Pará (1)
- Université de Montréal (1)
- Université de Montréal, Canada (16)
- University of Connecticut - USA (1)
- University of Michigan (162)
- University of Queensland eSpace - Australia (3)
- WestminsterResearch - UK (7)
- Worcester Research and Publications - Worcester Research and Publications - UK (1)
Resumo:
RNA viruses are excellent experimental models for studying evolution under the theoretical framework of population genetics. For a proper justification of this thesis we have introduced some properties of RNA viruses that are relevant for studying evolution. On the other hand, population genetics is a reductionistic theory of evolution. It does not consider or make simplistic assumptions on the transformation laws within and between genotypic and phenotypic spaces. However, such laws are minimized in the case of RNA viruses because the phenotypic space maps onto the genotypic space in a much more linear way than on higher DNA-based organisms. Under experimental conditions, we have tested the role of deleterious and beneficial mutations in the degree of adaptation of vesicular stomatitis virus (VSV), a nonsegmented virus of negative strand. We also have studied how effective population size, initial genetic variability in populations, and environmental heterogeneity shapes the impact of mutations in the evolution of vesicular stomatitis virus. Finally, in an integrative attempt, we discuss pros and cons of the quasispecies theory compared with classic population genetics models for haploid organisms to explain the evolution of RNA viruses.