16 resultados para Hannibal, 247 B.C.-182 B.C.
Filtro por publicador
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (1)
- Aquatic Commons (9)
- ARCA - Repositório Institucional da FIOCRUZ (1)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (1)
- Archive of European Integration (34)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (2)
- Aston University Research Archive (4)
- Biblioteca Digital | Sistema Integrado de Documentación | UNCuyo - UNCUYO. UNIVERSIDAD NACIONAL DE CUYO. (2)
- Biblioteca Digital da Câmara dos Deputados (4)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (6)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (5)
- Biblioteca Digital de Artesanías de Colombia (1)
- Biblioteca Digital de la Universidad Católica Argentina (2)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (5)
- Biblioteca Valenciana Digital - Ministerio de Educación, Cultura y Deporte - Valencia - Espanha (3)
- Bibloteca do Senado Federal do Brasil (5)
- Biodiversity Heritage Library, United States (2)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (16)
- Boston University Digital Common (2)
- Brock University, Canada (5)
- CaltechTHESIS (6)
- Cámara de Comercio de Bogotá, Colombia (1)
- Cambridge University Engineering Department Publications Database (35)
- CentAUR: Central Archive University of Reading - UK (5)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (88)
- Deakin Research Online - Australia (14)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (1)
- Digital Peer Publishing (1)
- DigitalCommons@The Texas Medical Center (7)
- DigitalCommons@University of Nebraska - Lincoln (1)
- Digitale Sammlungen - Goethe-Universität Frankfurt am Main (40)
- Duke University (1)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (8)
- Gallica, Bibliotheque Numerique - Bibliothèque nationale de France (French National Library) (BnF), France (51)
- Glasgow Theses Service (1)
- Harvard University (4)
- Helda - Digital Repository of University of Helsinki (16)
- Indian Institute of Science - Bangalore - Índia (130)
- Instituto Nacional de Saúde de Portugal (1)
- Lume - Repositório Digital da Universidade Federal do Rio Grande do Sul (2)
- Martin Luther Universitat Halle Wittenberg, Germany (1)
- Memoria Académica - FaHCE, UNLP - Argentina (9)
- Ministerio de Cultura, Spain (12)
- National Center for Biotechnology Information - NCBI (16)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (2)
- Portal de Revistas Científicas Complutenses - Espanha (2)
- Publishing Network for Geoscientific & Environmental Data (46)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (30)
- Queensland University of Technology - ePrints Archive (56)
- RCAAP - Repositório Científico de Acesso Aberto de Portugal (1)
- Repositório Digital da Universidade Municipal de São Caetano do Sul - USCS (1)
- Repositorio Institucional de la Universidad Nacional Agraria (8)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (22)
- School of Medicine, Washington University, United States (1)
- Universidad Autónoma de Nuevo León, Mexico (2)
- Universidad de Alicante (2)
- Universidad del Rosario, Colombia (4)
- Universidade Complutense de Madrid (2)
- Universidade Federal do Pará (8)
- Universidade Federal do Rio Grande do Norte (UFRN) (1)
- Universidade Metodista de São Paulo (1)
- Université de Lausanne, Switzerland (1)
- Université de Montréal, Canada (1)
- Université Laval Mémoires et thèses électroniques (1)
- University of Michigan (180)
- University of Queensland eSpace - Australia (5)
- University of Southampton, United Kingdom (1)
- University of Washington (9)
Resumo:
Cytokines are important regulators of hematopoesis. Mutations in gamma c, which is a subunit shared by the receptors for interleukin (IL) 2, IL-4, and IL-7, have been causally associated with human X chromosome-linked severe combined immunodeficiency disease. This finding indicates a mandatory role for cytokine receptor signaling at one or more stages of lymphocyte development. To evaluate the cellular level at which gamma c is critical for lymphopoiesis, the effect of monoclonal antibodies to gamma c on the capacity of syngeneic bone marrow cells to reconstitute the hematopoietic compartment of lethally irradiated recipient mice was examined. We show that monoclonal antibody to gamma c blocked lymphocyte development at or before the appearance of pro-B cells and prior to or at the seeding of the thymus by precursor cells while erythromyeloid cell development was normal. These results suggest that one level of lymphocyte development that requires gamma c is a point in hematopoietic cell differentiation near the divergence of lymphopoiesis and erythromyelopoesis.