3 resultados para wandering spleen

em Universidad Politécnica de Madrid


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En 1929 aparece el primer número de AA (L’architecture d’aujourd’hui), en 1932 existe un número-Monografía sobre los hermanos Perret, escrita por Pierre Vago, en 1946 se consolida como revista mensual y bajo la fundación de Andre Bloc. El primer número de AA que tengo en mi biblioteca es el número 34 (febrero-Marzo) de 1951. Mediante la lectura observada de una colección como AA, la determinación de unos capítulos representativos y la elección de imágenes de su tiempo se explican estos 57 años de arquitectura, cuyos resultados de un proceso temporal disfrutamos desde hace aproximadamente veinte años. A principio de los años cincuenta un grupo de jóvenes arquitectos, denso e intercomunicado en los congresos CIAM se propone situar la realidad de la arquitectura en los principios y realidades de su tiempo y de los que se intuyen futuro. Resultados de la Segunda Gran Guerra no son solo tragedias humanas sino gran investigación y desarrollo concretada industrialmente, enormes movimientos de personas en Europa y una sociedad enormemente optimista en USA, todo esto producirá las grandes transformaciones sociales de los 60’ y sus concreciones tecnológicas, políticas y desarrollo. Muchos arquitectos, publicaciones, concursos o decisiones políticas o privadas han producido el catalogo de arquitecturas de estos años, desde el CIAM IX hasta el POMPIDOU, desde la casa GEHRY hasta el KUNSTHAL, desde BRASILIA hasta SIDNEY, desde COPLEJIDAD Y CONTRADICCIÓN hasta DELIRIOS DE NY, desde OSAKA hasta MUNICH. En todas han existido un esfuerzo enorme por concretar la realidad de nuestras aspiraciones desde las puramente ideológicas de introspección social, hasta las concreciones de imagen directa. Varias líneas he abierto en mi proceso de investigación, las he llamado “anillos” porque todas estas líneas tienen similitud con los “anillos de crecimiento” de los árboles en cuanto a como se presentan en la estructura de formación y ha la cantidad de información no solo interna sino externa que aportan sobre la estructura árbol, su medio y la historia. Igual que podemos saber las temperaturas o las pluviometría que cubrieron Europa en la edad media solo estudiando los anillos de crecimiento de nuestro árboles (su grosor), de igual forma repasando LOS CONCURSOS y sus resultados que existieron en los últimos cincuenta años, podemos entender las aspiraciones y concreciones de las sociedades y sus arquitectos en este tiempo. Cuatro capítulos, los mas determinantes son los elegidos para dar cuerpo a una TESIS de tamaño capaz: Las ideas, el futuro, las referencias y el presente son los capítulos que de forma visual intentan explicar el fruto arquitectónico, sus aspiraciones y sus concreciones. Las ideas sin ninguna duda, pertenecen a los padres de nuestro tiempo, son las del Team X, la reflexión sobre lo perecedero, las realidades programáticas, densidades o lo publico-privado son solo planetas en el universo de sus ideas. El futuro lo trazaron aquellos que empezaron a investigar, concretar o reflexionar sobre la incidencia tanto de los procesos industriales con sus nuevos materiales como de las nuevas concreciones urbanas que los movimientos migratorios producirían en las ciudades. Las referencias son las bibliotecas de carácter informativo-visual que han generado nuestro inventario icónico. El presente son las imágenes de referencia de nuestro tiempo-mediático, no solo las produce un arquitecto (en este caso R.Koolhas), pero si que es verdad que en las imágenes arquitectónicas de OMA se concreta todo el catalogo de arquitecturas del presente. ENGLISH SUMMARY The fisrt AA (l´Architecture d´Aujourd´hui) issue was published in 1929, three years later, in 1932, a monographic issue on Perret brothers was written by Pierre Vago and in 1946 the magazine was strongly established as a monthly publication under the direction of André Bloc. The oldest copy I own on my bookshelves is nº 34 printed in February-March 1951. While carefully reading a collection such as AA we are able to extract representative chapters and images that can explain a linear process lasting 57 years of fruitful architectural production of which consequences we have been enjoying the past twenty years. In the early fifties a compact group of young architects linked by the CIAM congress decided to encompass architectural reality to the needs and principles of their time. Not only big human tragedies arose from the Second World War but also some of the fastest industrial inventions due to a powerful will to development, that altogether with european migrations and a high standard of optimism in the United States headed to the peak transformations of the sixties and their technological and political development. A bunch of architects, magazines and architectural competitions sided by political and private decisions produced the architectural catalogue of those years, from CIAM IX to the Pompidou art centre, from Gerhy´s house to the Kunsthal museum, from Brasilia to Sidney, from “Complexity and Contradiction“ to “Delirious NY” and from Osaka all the way to Munich. All of them carried a vast effort towards the concretion of will, from social introspection to a more effective development of images. Several paths run across my investigation, namely “the rings”, as they tend to behave as a growing structure like a tree trunk, providing internal and external information not only of the vegetal element but also of the environment and events crossing its time. In the same direction as we are able to predict the weather in the Middle Age by means of studying our forests, we can use the architectural competitions ant their results for the past fifty years to understand the will and ambitions of these developing societies and their architects. To give shape to a sizeable thesis the selected information has been packed in four chapters: Ideas, Future, References and Present, each of them structured as an Image bank visualizing the architectural product, its will and specific ambition. The first group, Ideas, is devoted entirely to the step-fathers of present architecture, with ideas that belong to TEAM X and embrace the reflection about the transitory, the programmatic reality, density or the public-private debate as wandering planets of their ideal universe. The second group is dedicated to a Future that was traced by those engaged on industrial processes and new material investigation together with some others exploring new urban concretions brought to existence by the pressure of the after war migrations. The third group, References, have been shaped as a stock-list containing all our iconic cross-references. The last group, Present, brings together the icons of this media-time we live in and not only those produced by one single architect (Rem Koolhaas) even if his production embodies all architectural references at the moment.

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The progressive ageing of population has turned the mild cognitive impairment (MCI) into a prevalent disease suffered by elderly. Consequently, the spatial disorientation has become a significant problem for older people and their caregivers. The ambient-assisted living applications are offering location-based services for empowering elderly to go outside and encouraging a greater independence. Therefore, this paper describes the design and technical evaluation of a location-awareness service enabler aimed at supporting and managing probable wandering situations of a person with MCI. Through the presence capabilities of the IP multimedia subsystem (IMS) architecture, the service will alert patient's contacts if a hazardous situation is detected depending on his location. Furthermore, information about the older person's security areas has been included in the user profile managed by IMS. In doing so, the service enabler introduced contribute to “context-awareness” paradigm allowing the adaptation and personalization of services depending on user's context and specific conditions or preferences.

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This work presents the first application of total-reflection X-ray fluorescence (TXRF) spectrometry, a new and powerful alternative analytical method, to evaluation of the bioaccumulation kinetics of gold nanorods (GNRs) in various tissues upon intravenous administration in mice. The analytical parameters for developed methodology by TXRF were evaluated by means of the parallel analysis of bovine liver certified reference material samples (BCR-185R) doped with 10 μg/g gold. The average values (n = 5) achieved for gold measurements in lyophilized tissue weight were as follows: recovery 99.7%, expanded uncertainty (k = 2) 7%, repeatability 1.7%, detection limit 112 ng/g, and quantification limit 370 ng/g. The GNR bioaccumulation kinetics was analyzed in several vital mammalian organs such as liver, spleen, brain, and lung at different times. Additionally, urine samples were analyzed to study the kinetics of elimination of the GNRs by this excretion route. The main achievement was clearly differentiating two kinds of behaviors. GNRs were quickly bioaccumulated by highly vascular filtration organs such as liver and spleen, while GNRs do not show a bioaccumulation rates in brain and lung for the period of time investigated. In parallel, urine also shows a lack of GNR accumulation. TXRF has proven to be a powerful, versatile, and precise analytical technique for the evaluation of GNRs content in biological systems and, in a more general way, for any kind of metallic nanoparticles.