Mechanical behaviour and rupture of normal and pathological human ascending aortic wall

The mechanical properties of aortic wall, both healthy and pathological, are needed in order to develop and improve diagnostic and interventional criteria, and for the development of mechanical models to assess arterial integrity. This study focuses on the mechanical behaviour and rupture conditions of the human ascending aorta and its relationship with age and pathologies. Fresh ascending aortic specimens harvested from 23 healthy donors, 12 patients with bicuspid aortic valve (BAV) and 14 with aneurysm were tensile-tested in vitro under physiological conditions. Tensile strength, stretch at failure and elbow stress were measured. The obtained results showed that age causes a major reduction in the mechanical parameters of healthy ascending aortic tissue, and that no significant differences are found between the mechanical strength of aneurysmal or BAV aortic specimens and the corresponding age-matched control group. The physiological level of the stress in the circumferential direction was also computed to assess the physiological operation range of healthy and diseased ascending aortas. The mean physiological wall stress acting on pathologic aortas was found to be far from rupture, with factors of safety (defined as the ratio of tensile strength to the mean wall stress) larger than six. In contrast, the physiological operation of pathologic vessels lays in the stiff part of the response curve, losing part of its function of damping the pressure waves from the heart.

Coastal floods and decadal changes: the climate factor

Observation has widely shown for nearly all last century that the Spanish (Dynamic) Maritime Climate was following around 10 to 11 year cycles in its most significant figure, wind wave, despite it being better to register cycles of 20 to 22 years, in analogical way with the semi-diurnal and diurnal cycles of Cantabrian tides. Those cycles were soon linked to sun activity and, at the end of the century, the latter was related to the Solar System evolution. We know now that waves and storm surges are coupled and that (Dynamic) Maritime Climate forms part of a more complex “Thermal Machine” including Hydrological cycle. The analysis of coastal floods could so facilitate the extension of that experience. According to their immediate cause, simple flood are usually sorted out into flash, pluvial, fluvial, groundwater and coastal types, considering the last as caused by sea waters. But the fact is that most of coastal floods are the result of the concomitance of several former simple types. Actually, the several Southeastern Mediterranean coastal flood events show to be the result of the superposition within the coastal zone of flash, fluvial, pluvial and groundwater flood types under boundary condition imposed by the concomitant storm sea level rise. This work shall be regarded as an attempt to clarify that cyclic experience, through an in-depth review of a past flood events in Valencia (Turia and Júcar basins), as in Murcia (Segura’s) as well.

Tracing environmental and cultural changes throughout the Gran Dolina TD10 Middle Pleistocene sequence (Atapuerca, Burgos, Spain)

The well-known eponym El Sidrón has a very special history. It started with the development of a karstic system between two types of rock (sandstone and Neogene conglomerates) as a result of the flow of a small stream. It continued with the use of the cave as a refuge and a hiding place during the Spanish Civil War and the aftermath and with the presence of some endemic species of bats and cave insects

Examining wheat yield sensitivity to temperature and precipitation changes for a large ensemble of crop models using impact response surfaces

Impact response surfaces (IRSs) depict the response of an impact variable to changes in two explanatory variables as a plotted surface. Here, IRSs of spring and winter wheat yields were constructed from a 25-member ensemble of process-based crop simulation models. Twenty-one models were calibrated by different groups using a common set of calibration data, with calibrations applied independently to the same models in three cases. The sensitivity of modelled yield to changes in temperature and precipitation was tested by systematically modifying values of 1981-2010 baseline weather data to span the range of 19 changes projected for the late 21st century at three locations in Europe.