Explaining light vehicle demand evolution in interurban toll roads: a dynamic panel data analysis in Spain

Tolls have increasingly become a common mechanism to fund road projects in recent decades. Therefore, improving knowledge of demand behavior constitutes a key aspect for stakeholders dealing with the management of toll roads. However, the literature concerning demand elasticity estimates for interurban toll roads is still limited due to their relatively scarce number in the international context. Furthermore, existing research has left some aspects to be investigated, among others, the choice of GDP as the most common socioeconomic variable to explain traffic growth over time. This paper intends to determine the variables that better explain the evolution of light vehicle demand in toll roads throughout the years. To that end, we establish a dynamic panel data methodology aimed at identifying the key socioeconomic variables explaining changes in light vehicle demand over time. The results show that, despite some usefulness, GDP does not constitute the most appropriate explanatory variable, while other parameters such as employment or GDP per capita lead to more stable and consistent results. The methodology is applied to Spanish toll roads for the 1990?2011 period, which constitutes a very interesting case on variations in toll road use, as road demand has experienced a significant decrease since the beginning of the economic crisis in 2008.

Selection, training and validation process of a sensory panel for bread analysis: Influence of cultivar on the quality of breads made from common wheat and spelta wheat

A protocol of selection, training and validation of the members of the panel for bread sensory analysis is proposed to assess the influence of wheat cultivar on the sensory quality of bread. Three cultivars of bread wheat and two cultivars of spelt wheat organically-grown under the same edaphoclimatic conditions were milled and baked using the same milling and baking procedure. Through the use of triangle tests, differences were identified between the five breads. Significant differences were found between the spelt breads and those made with bread wheat for the attributes ?crumb cell homogeneity? and ?crumb elasticity?. Significant differences were also found for the odor and flavor attributes, with the bread made with ?Espelta Navarra? being the most complex, from a sensory point of view. Based on the results of this study, we propose that sensory properties should be considered as breeding criteria for future work on genetic improvement.

Identification of a biomarker panel for colorectal cancer diagnosis

Background Malignancies arising in the large bowel cause the second largest number of deaths from cancer in the Western World. Despite progresses made during the last decades, colorectal cancer remains one of the most frequent and deadly neoplasias in the western countries. Methods A genomic study of human colorectal cancer has been carried out on a total of 31 tumoral samples, corresponding to different stages of the disease, and 33 non-tumoral samples. The study was carried out by hybridisation of the tumour samples against a reference pool of non-tumoral samples using Agilent Human 1A 60-mer oligo microarrays. The results obtained were validated by qRT-PCR. In the subsequent bioinformatics analysis, gene networks by means of Bayesian classifiers, variable selection and bootstrap resampling were built. The consensus among all the induced models produced a hierarchy of dependences and, thus, of variables. Results After an exhaustive process of pre-processing to ensure data quality--lost values imputation, probes quality, data smoothing and intraclass variability filtering--the final dataset comprised a total of 8, 104 probes. Next, a supervised classification approach and data analysis was carried out to obtain the most relevant genes. Two of them are directly involved in cancer progression and in particular in colorectal cancer. Finally, a supervised classifier was induced to classify new unseen samples. Conclusions We have developed a tentative model for the diagnosis of colorectal cancer based on a biomarker panel. Our results indicate that the gene profile described herein can discriminate between non-cancerous and cancerous samples with 94.45% accuracy using different supervised classifiers (AUC values in the range of 0.997 and 0.955)

Identification of a biomarker panel for colorectal cancer diagnosis

Background:Malignancies arising in the large bowel cause the second largest number of deaths from cancer in the Western World. Despite progresses made during the last decades, colorectal cancer remains one of the most frequent and deadly neoplasias in the western countries. Methods: A genomic study of human colorectal cancer has been carried out on a total of 31 tumoral samples, corresponding to different stages of the disease, and 33 non-tumoral samples. The study was carried out by hybridisation of the tumour samples against a reference pool of non-tumoral samples using Agilent Human 1A 60-mer oligo microarrays. The results obtained were validated by qRT-PCR. In the subsequent bioinformatics analysis, gene networks by means of Bayesian classifiers, variable selection and bootstrap resampling were built. The consensus among all the induced models produced a hierarchy of dependences and, thus, of variables. Results: After an exhaustive process of pre-processing to ensure data quality--lost values imputation, probes quality, data smoothing and intraclass variability filtering--the final dataset comprised a total of 8, 104 probes. Next, a supervised classification approach and data analysis was carried out to obtain the most relevant genes. Two of them are directly involved in cancer progression and in particular in colorectal cancer. Finally, a supervised classifier was induced to classify new unseen samples. Conclusions: We have developed a tentative model for the diagnosis of colorectal cancer based on a biomarker panel. Our results indicate that the gene profile described herein can discriminate between non-cancerous and cancerous samples with 94.45% accuracy using different supervised classifiers (AUC values in the range of 0.997 and 0.955).

Explicit Expressions for Solar Panel Equivalent Circuit Parameters Based on Analytical Formulation and the Lambert W-Function

Due to the high dependence of photovoltaic energy efficiency on environmental conditions (temperature, irradiation...), it is quite important to perform some analysis focusing on the characteristics of photovoltaic devices in order to optimize energy production, even for small-scale users. The use of equivalent circuits is the preferred option to analyze solar cells/panels performance. However, the aforementioned small-scale users rarely have the equipment or expertise to perform large testing/calculation campaigns, the only information available for them being the manufacturer datasheet. The solution to this problem is the development of new and simple methods to define equivalent circuits able to reproduce the behavior of the panel for any working condition, from a very small amount of information. In the present work a direct and completely explicit method to extract solar cell parameters from the manufacturer datasheet is presented and tested. This method is based on analytical formulation which includes the use of the Lambert W-function to turn the series resistor equation explicit. The presented method is used to analyze commercial solar panel performance (i.e., the current-voltage–I-V–curve) at different levels of irradiation and temperature. The analysis performed is based only on the information included in the manufacturer’s datasheet.

Explicit expressions for solar panel equivalent circuit parameters based on analytical formulation and the Lambert W - Function

Due to the high dependence of photovoltaic energy efficiency on environmental conditions (temperature, irradiation...), it is quite important to perform some analysis focusing on the characteristics of photovoltaic devices in order to optimize energy production, even for small-scale users. The use of equivalent circuits is the preferred option to analyze solar cells/panels performance. However, the aforementioned small-scale users rarely have the equipment or expertise to perform large testing/calculation campaigns, the only information available for them being the manufacturer datasheet. The solution to this problem is the development of new and simple methods to define equivalent circuits able to reproduce the behavior of the panel for any working condition, from a very small amount of information. In the present work a direct and completely explicit method to extract solar cell parameters from the manufacturer datasheet is presented and tested. This method is based on analytical formulation which includes the use of the Lambert W-function to turn the series resistor equation explicit. The presented method is used to analyze the performance (i.e., the I - V curve) of a commercial solar panel at different levels of irradiation and temperature. The analysis performed is based only on the information included in the manufacturer's datasheet.

Vibro-acoustic analysis of spacecraft structures with thin air layers

Esta Tesis presenta un estudio sobre el comportamiento vibroacústico de estructuras espaciales que incluyen capas de aire delgadas, así como sobre su modelización numérica. Las capas de aire pueden constituir un elemento fundamental en estos sistemas, como paneles solares plegados, que se consideran el caso de estudio en este trabajo. Para evaluar la influencia de las capas de aire en la respuesta dinámica del sistema se presenta el uso de modelos unidimensionales. La modelización de estos sistemas se estudia para los rangos de baja y alta frecuencia. En el rango de baja frecuencia se propone un conjunto de estrategias de simulación basadas en técnicas numéricas que se utilizan habitualmente en la industria aeroespacial para facilitar la aplicación de los resultados de la Tesis en los modelos numéricos actuales. Los resultados muestran el importante papel de las capas de aire en la respuesta del sistema. El uso de modelos basados en elementos finitos o de contorno para estos elementos proporciona resultados equivalentes aunque la aplicabilidad de estos últimos puede estar condicionada por la geometría del problema. Se estudia asimismo el uso del Análisis Estadístico de la Energía (SEA) para estos elementos. Una de las estrategias de simulación propuestas, que incluye una formulación energética para el aire que rodea a la estructura, se propone como estimador preliminar de la respuesta del sistema y sus frecuencias propias. Para el rango de alta frecuencia, se estudia la influencia de la definición del propio modelo SEA. Se presenta el uso de técnicas de reducción para determinar una matriz de pérdidas SEA reducida para definiciones incompletas del sistema (si algún elemento que interactúa con el resto no se incluye en el modelo). Esta nueva matriz tiene en cuenta la contribución de las subestructuras que no se consideran parte del modelo y que suelen ignorarse en el procedimiento habitual para reducir el tamaño del mismo. Esta matriz permite también analizar sistemas que incluyen algún componente con problemas de accesibilidad para medir su respuesta. Respecto a la determinación de los factores de pérdidas del sistema, se presenta una metodología que permite abordar casos en los que el método usual, el Método de Inyección de Potencia (PIM), no puede usarse. Se presenta un conjunto de métodos basados en la técnicas de optimización y de actualización de modelos para casos en los que no se puede medir la respuesta de todos los elementos del sistema y también para casos en los que no todos los elementos pueden ser excitados, abarcando un conjunto de casos más amplio que el abordable con el PIM. Para ambos rangos de frecuencia se presentan diferentes casos de análisis: modelos numéricos para validar los métodos propuestos y un panel solar plegado como caso experimental que pone de manifiesto la aplicación práctica de los métodos presentados en la Tesis. ABSTRACT This Thesis presents an study on the vibro-acoustic behaviour of spacecraft structures with thin air layers and their numerical modelling. The air layers can play a key role in these systems as solar wings in folded configuration that constitute the study case for this Thesis. A method based on one-dimensional models is presented to assess the influence of the air layers in the dynamic response of the system. The modelling of such systems is studied for low and high frequency ranges. In the low frequency range a set of modelling strategies are proposed based on numerical techniques used in the industry to facilitate the application of the results in the current numerical models. Results show the active role of the air layers in the system response and their great level of influence. The modelling of these elements by means of Finite Elements (FE) and Boundary Elements (BE) provide equivalent results although the applicability of BE models can be conditioned by the geometry of the problem. The use of Statistical Energy Analysis (SEA) for these systems is also presented. Good results on the system response are found for models involving SEA beyond the usual applicability limit. A simulation strategy, involving energetic formulation for the surrounding fluid is proposed as fast preliminary approach for the system response and the coupled eigenfrequencies. For the high frequency range, the influence of the definition of the SEA model is presented. Reduction techniques are used to determine a Reduced SEA Loss Matrix if the system definition is not complete and some elements, which interact with the rest, are not included. This new matrix takes into account the contribution of the subsystems not considered that are neglected in the usual approach for decreasing the size of the model. It also allows the analysis of systems with accessibility restrictions on some element in order to measure its response. Regarding the determination of the loss factors of a system, a methodology is presented for cases in which the usual Power Injection Method (PIM) can not be applied. A set of methods are presented for cases in which not all the subsystem responses can be measured or not all the subsystems can be excited, as solar wings in folded configuration. These methods, based on error minimising and model updating techniques can be used to calculate the system loss factors in a set of cases wider than the PIM’s. For both frequency ranges, different test problems are analysed: Numerical models are studied to validate the methods proposed; an experimental case consisting in an actual solar wing is studied on both frequency ranges to highlight the industrial application of the new methods presented in the Thesis.

Analysis of the impact of globalization and economic growth on food security in developing countries

A pesar de los importantes avances en la reducción del hambre, la seguridad alimentaria continúa siendo un reto de dimensión internacional. La seguridad alimentaria es un concepto amplio y multidimensional, cuyo análisis abarca distintas escalas y horizontes temporales. Dada su complejidad, la identificación de las causas de la inseguridad alimentaria y la priorización de las medias para abordarlas, son dos cuestiones que suscitan un intenso debate en la actualidad. El objetivo de esta tesis es evaluar el impacto de la globalización y el crecimiento económico en la seguridad alimentaria en los países en desarrollo, desde una perspectiva macro y un horizonte temporal a largo plazo. La influencia de la globalización se aborda de una manera secuencial. En primer lugar, se analiza la relación entre la inversión público-privada en infraestructuras y las exportaciones agrarias. A continuación, se estudia el impacto de las exportaciones agrarias en los indicadores de seguridad alimentaria. El estudio del impacto del crecimiento económico aborda los cambios paralelos en la distribución de la renta, y cómo la inequidad influye en el comportamiento de la seguridad alimentaria nacional. Además, se analiza en qué medida el crecimiento económico contribuye a acelerar el proceso de mejora de la seguridad alimentaria. Con el fin de conseguir los objetivos mencionados, se llevan a cabo varios análisis econométricos basados en datos de panel, en el que se combinan datos de corte transversal de 52 países y datos temporales comprendidos en el periodo 1991-2012. Se analizan tanto variables en niveles como variables en tasas de cambio anual. Se aplican los modelos de estimación de efectos variables y efectos fijos, ambos en niveles y en primeras diferencias. La tesis incluye cuatro tipos de modelos econométricos, cada uno de ellos con sus correspondientes pruebas de robustez y especificaciones. Los resultados matizan la importancia de la globalización y el crecimiento económico como mecanismos de mejora de la seguridad alimentaria en los países en desarrollo. Se obtienen dos conclusiones relativas a la globalización. En primer lugar, los resultados sugieren que la promoción de las inversiones privadas en infraestructuras contribuye a aumentar las exportaciones agrarias. En segundo lugar, se observa que las exportaciones agrarias pueden tener un impacto negativo en los indicadores de seguridad alimentaria. La combinación de estas dos conclusiones sugiere que la apertura comercial y financiera no contribuye por sí misma a la mejora de la seguridad alimentaria en los países en desarrollo. La apertura internacional de los países en desarrollo ha de ir acompañada de políticas e inversiones que desarrollen sectores productivos de alto valor añadido, que fortalezcan la economía nacional y reduzcan su dependencia exterior. En relación al crecimiento económico, a pesar del incuestionable hecho de que el crecimiento económico es una condición necesaria para reducir los niveles de subnutrición, no es una condición suficiente. Se han identificado tres estrategias adicionales que han de acompañar al crecimiento económico con el fin de intensificar su impacto positivo sobre la subnutrición. Primero, es necesario que el crecimiento económico sea acompañado de una distribución más equitativa de los ingresos. Segundo, el crecimiento económico ha de reflejarse en un aumento de inversiones en salud, agua y saneamiento y educación. Se observa que, incluso en ausencia de crecimiento económico, mejoras en el acceso a agua potable contribuyen a reducir los niveles de población subnutrida. Tercero, el crecimiento económico sostenible en el largo plazo parece tener un mayor impacto positivo sobre la seguridad alimentaria que el crecimiento económico más volátil o inestable en el corto plazo. La estabilidad macroeconómica se identifica como una condición necesaria para alcanzar una mayor mejora en la seguridad alimentaria, incluso habiéndose mejorado la equidad en la distribución de los ingresos. Por último, la tesis encuentra que los países en desarrollo analizados han experimentado diferentes trayectorias no lineales en su proceso de mejora de sus niveles de subnutrición. Los resultados sugieren que un mayor nivel inicial de subnutrición y el crecimiento económico son responsables de una respuesta más rápida al reto de la mejora de la seguridad alimentaria. ABSTRACT Despite the significant reductions of hunger, food security still remains a global challenge. Food security is a wide concept that embraces multiple dimensions, and has spatial-temporal scales. Because of its complexity, the identification of the drivers underpinning food insecurity and the prioritization of measures to address them are a subject of intensive debate. This thesis attempts to assess the impact of globalization and economic growth on food security in developing countries with a macro level scale (country) and using a long-term approach. The influence of globalization is addressed in a sequential way. First, the impact of public-private investment in infrastructure on agricultural exports in developing countries is analyzed. Secondly, an assessment is conducted to determine the impact of agricultural exports on food security indicators. The impact of economic growth focuses on the parallel changes in income inequality and how the income distribution influences countries' food security performance. Furthermore, the thesis analyzes to what extent economic growth helps accelerating food security improvements. To address the above mentioned goals, various econometric models are formulated. Models use panel data procedures combining cross-sectional data of 52 countries and time series data from 1991 to 2012. Yearly data are expressed both in levels and in changes. The estimation models applied are random effects estimation and fixed effects estimations, both in levels and in first differences. The thesis includes four families of econometric models, each with its own set of robustness checks and specifications. The results qualify the relevance of globalization and economic growth as enabling mechanisms for improving food security in developing countries. Concerning globalization, two main conclusions can be drawn. First, results showed that enhancing foreign private investment in infrastructures contributes to increase agricultural exports. Second, agricultural exports appear to have a negative impact on national food security indicators. These two conclusions suggest that trade and financial openness per se do not contribute directly to improve food security in development countries. Both measures should be accompanied by investments and policies to support the development of national high value productive sectors, to strengthen the domestic economy and reduce its external dependency. Referring to economic growth, despite the unquestionable fact that income growth is a pre-requisite for reducing undernourishment, results suggest that it is a necessary but not a sufficient condition. Three additional strategies should accompany economic growth to intensifying its impact on food security. Firstly, it is necessary that income growth should be accompanied by a better distribution of income. Secondly, income growth needs to be followed by investments and policies in health, sanitation and education to improve food security. Even if economic growth falters, sustained improvements in the access to drinking water may still give rise to reductions in the percentage of undernourished people. And thirdly, long-term economic growth appears to have a greater impact on reducing hunger than growth regimes that combine periods of growth peaks followed by troughs. Macroeconomic stability is a necessary condition for accelerating food security. Finally, the thesis finds that the developing countries analyzed have experienced different non-linear paths toward improving food security. Results also show that a higher initial level of undernourishment and economic growth result in a faster response for improving food security.

Evolution over time of heavy vehicle volume in toll roads: A dynamic panel data to identify key explanatory variables in Spain

Improving the knowledge of demand evolution over time is a key aspect in the evaluation of transport policies and in forecasting future investment needs. It becomes even more critical for the case of toll roads, which in recent decades has become an increasingly common device to fund road projects. However, literature regarding demand elasticity estimates in toll roads is sparse and leaves some important aspects to be analyzed in greater detail. In particular, previous research on traffic analysis does not often disaggregate heavy vehicle demand from the total volume, so that the specific behavioral patternsof this traffic segment are not taken into account. Furthermore, GDP is the main socioeconomic variable most commonly chosen to explain road freight traffic growth over time. This paper seeks to determine the variables that better explain the evolution of heavy vehicle demand in toll roads over time. To that end, we present a dynamic panel data methodology aimed at identifying the key socioeconomic variables that explain the behavior of road freight traffic throughout the years. The results show that, despite the usual practice, GDP may not constitute a suitable explanatory variable for heavy vehicle demand. Rather, considering only the GDP of those sectors with a high impact on transport demand, such as construction or industry, leads to more consistent results. The methodology is applied to Spanish toll roads for the 1990?2011 period. This is an interesting case in the international context, as road freight demand has experienced an even greater reduction in Spain than elsewhere, since the beginning of the economic crisis in 2008.

Whole-genome genotyping of grape using a panel of microsatellite

The use of microsatellite markers in large-scale genetic studies is limited by its low throughput and high cost and labor requirements. Here, we provide a panel of 45 multiplex PCRs for fast and cost-efficient genome-wide fluorescence-based microsatellite analysis in grapevine. The developed multiplex PCRs panel (with up to 15-plex) enables the scoring of 270 loci covering all the grapevine genome (9 to 20 loci/chromosome) using only 45 PCRs and sequencer runs. The 45 multiplex PCRs were validated using a diverse grapevine collection of 207 accessions, selected to represent most of the cultivated Vitis vinifera genetic diversity. Particular attention was paid to quality control throughout the whole process (assay replication, null allele detection, ease of scoring). Genetic diversity summary statistics and features of electrophoretic profiles for each studied marker are provided, as are the genotypes of 25 common cultivars that could be used as references in other studies.

Contribution to the analysis and design of reflectarray antennas for reconfigurable beam applications at frequencies above 100 GHz using liquid crystal technology

El trabajo contenido en esta tesis doctoral está encuadrado en el desarrollo de antenas reconfigurables electrónicamente capaces de proporcionar prestaciones competitivas a las aplicaciones cada vez más comunes que operan a frecuencias superiores a 60 GHz. En concreto, esta tesis se centra en el estudio, diseño, e implementación de las antenas reflectarray, a las que se introduce la tecnología de cristal líquido como elemento característico con el que se consigue reconfigurabilidad de haz de forma electrónica. Desde un punto de vista muy general, se puede describir un cristal líquido como un material cuya permitividad eléctrica es variable y controlada por una excitación externa, que generalmente suele corresponderse con un campo eléctrico quasi-estático (AC). Las antenas reflectarray de cristal líquido se han escogido como objeto de estudio por varias razones. La primera de ellas tiene que ver con las ventajas que los reflectarrays, y en especial aquellos realizados en configuración planar, proporcionan con respecto a otras antenas de alta ganancia como los reflectores o los “phased-arrays”. En los reflectarrays, la alimentación a través de una fuente primaria común (característica de reflectores) y el elevado número de grados de libertad de las celdas que los componen (característica de arrays) hacen que estas antenas puedan proporcionar prestaciones eléctricas iguales o mejores que las anteriores, a un coste más reducido y con estructuras de antena más compactas. La segunda razón radica en la flexibilidad que ofrece el cristal líquido a ser confinado y polarizado en recintos de geometría variada, como consecuencia de su fluidez (propiedad de los líquidos). Por ello, la tecnología de cristal líquido permite que el propio elemento reconfigurable en las celdas de reflectarray se adapte a la configuración planar de manera que en sí mismo, el cristal líquido sea una o varias de las capas características de esta configuración. Esto simplifica de forma drástica la estructura y la fabricación de este tipo de antenas, incluso si se comparan con reflectarrays reconfigurables basados en otras tecnologías como diodos, MEMS, etc. Por tanto, su coste y desarrollo es muy reducido, lo que hace que se puedan fabricar reflectarrays reconfigurables eléctricamente grandes, a bajo coste, y en producción elevada. Un ejemplo claro de una estructura similar, y que ha tenido éxito comercial, son las pantallas de cristal líquido. La tercera razón reside en el hecho de que el cristal líquido es, hasta la fecha, de las pocas tecnologías capaces de ofrecer reconfigurabilidad del haz a frecuencias superiores a 60 GHz. De hecho, el cristal líquido permite reconfigurabilidad en un amplio margen de frecuencias, que va desde DC a frecuencias del espectro visible, incluyendo las microondas y los THz. Otras tecnologías, como los materiales ferroeléctricos, el grafeno o la tecnología CMOS “on chip” permiten también conmutar el haz en estas frecuencias. Sin embargo, la tecnología CMOS tiene un elevado coste y actualmente está limitada a frecuencias inferiores a 150 GHz, y aunque los materiales ferroeléctricos o el grafeno puedan conmutar a frecuencias más altas y en un rango más amplio, tienen serias dificultades que los hacen aún inmaduros. En el caso de los materiales ferroeléctricos, los elevados voltajes para conmutar el material los hacen poco atractivos, mientras que en el caso del grafeno, su modelado aún está en discusión, y todavía no se han arrojado resultados experimentales que validen su idoneidad. Estas tres razones hacen que los reflectarrays basados en cristal líquido sean atractivos para multitud de aplicaciones de haz reconfigurable a frecuencias superiores a 60 GHz. Aplicaciones como radar de escaneo de imágenes de alta resolución, espectroscopia molecular, radiómetros para observación atmosférica, o comunicaciones inalámbricas de alta frecuencia (WiGig) son algunas de ellas. La tesis está estructurada en tres partes. En la primera de ellas se describen las características más comunes de los cristales líquidos, centrándonos en detalle en aquellas propiedades ofrecidas por este material en fase nemática. En concreto, se estudiará la anisotropía dieléctrica (Ae) de los cristales líquidos uniaxiales, que son los que se emplean en esta tesis, definida como la diferencia entre la permitividad paralela (£//) y la perpendicular (e±): Ae = e,, - e±. También se estudiará la variación de este parámetro (Ae) con la frecuencia, y el modelado electromagnético macroscópico más general que, extraído a partir de aquella, permite describir el cristal líquido para cada tensión de polarización en celdas de geometría planar. Este modelo es de suma importancia para garantizar precisión en el desfasaje proporcionado por las diferentes celdas reconfigurables para reflectarrays que se describirán en la siguiente parte de la tesis. La segunda parte de la tesis se centra en el diseño de celdas reflectarray resonantes basadas en cristal líquido. La razón por la que se escogen estos tipos de celdas reside en el hecho de que son las únicas capaces de proporcionar rangos de fase elevados ante la reducida anisotropía dieléctrica que ofrecen los cristales líquidos. El objetivo de esta parte trata, por tanto, de obtener estructuras de celdas reflectarray que sean capaces de proporcionar buenas prestaciones eléctricas a nivel de antena, mejorando sustancialmente las prestaciones de las celdas reportadas en el estado del arte, así como de desarrollar una herramienta de diseño general para aquellas. Para ello, se estudian las prestaciones eléctricas de diferentes tipos de elementos resonantes de cristal líquido que van, desde el más sencillo, que ha limitado el estado de la técnica hasta el desarrollo de esta tesis y que está formado por un sólo resonador, a elementos que constan de varios resonadores (multi-resonantes) y que pueden ser monocapa o multicapa. En un primer paso, el procedimiento de diseño de estas estructuras hace uso de un modelo convencional de cristal líquido que ha venido siendo usado en el estado del arte para este tipo de celdas, y que considera el cristal líquido como un material homogéneo e isótropo cuya permitividad varía entre (e/7) y (e±). Sin embargo, en esta parte de la tesis se demuestra que dicho modelado no es suficiente para describir de forma genérica el comportamiento del cristal líquido en las celdas tipo reflectarray. En la tesis se proponen procedimientos más exactos para el análisis y diseño basados en un modelo más general que define el cristal líquido como un material anisótropo e inhomogeneo en tres dimensiones, y se ha implementado una técnica que permite optimizar celdas multi-resonantes de forma eficiente para conseguir elevadas prestaciones en cuanto a ancho de banda, rango de fase, pérdidas, o sensibilidad al ángulo de incidencia. Los errores cometidos en el uso del modelado convencional a nivel de celda (amplitud y fase) se han analizado para varias geometrías, usando medidas de varios prototipos de antena que usan un cristal líquido real a frecuencias superiores a 100 GHz. Las medidas se han realizado en entorno periódico mediante un banco cuasi-óptico, que ha sido diseñado especialmente para este fin. Uno de estos prototipos se ha optimizado a 100 GHz para conseguir un ancho de banda relativamente elevado (10%), pérdidas reducidas, un rango de fase mayor de 360º, baja sensibilidad al ángulo de incidencia, y baja influencia de la inhomogeneidad transversal del cristal líquido en la celda. Estas prestaciones a nivel de celda superan de forma clara aquellas conseguidas por otros elementos que se han reportado en la literatura, de manera que dicho prototipo se ha usado en la última parte de la tesis para realizar diversas antenas de barrido. Finalmente, en esta parte se presenta una estrategia de caracterización de la anisotropía macroscópica a partir de medidas de los elementos de reflectarray diseñados en banco cuasi-óptico, obteniendo resultados tanto en las frecuencias de interés en RF como en AC, y comparándolas con aquellas obtenidas mediante otros métodos. La tercera parte de la tesis consiste en el estudio, diseño, fabricación y medida de antenas reconfigurables basadas en cristal líquido en configuraciones complejas. En reflectarrays pasivos, el procedimiento de diseño de la antena se limita únicamente al ajuste en cada celda de la antena de las dimensiones de las metalizaciones que se emplean para el control de fase, mediante procesos de optimización bien conocidos. Sin embargo, en el caso de reflectarrays reconfigurables basados en cristal líquido, resulta necesario un paso adicional, que consiste en calcular de forma adecuada las tensiones de control en cada celda del reflectarray para configurar la fase requerida en cada una de ellas, así como diseñar la estructura y los circuitos de control que permitan direccionar a cada elemento su tensión correspondiente. La síntesis de tensiones es por tanto igual o más importante que el diseño de la geometría de las celdas, puesto que éstas son las que están directamente relacionadas con la fase. En el estado del arte, existen varias estrategias de síntesis de tensiones que se basan en la caracterización experimental de la curva de fase respecto al voltaje. Sin embargo, esta caracterización sólo puede hacerse a un solo ángulo de incidencia y para unas determinadas dimensiones de celda, lo que produce que las tensiones sintetizadas sean diferentes de las adecuadas, y en definitiva que se alcancen errores de fase mayores de 70º. De esta forma, hasta la fecha, las prestaciones a nivel de antena que se han conseguido son reducidas en cuanto a ancho de banda, rango de escaneo o nivel de lóbulos secundarios. En esta última parte de la tesis, se introduce una nueva estrategia de síntesis de tensiones que es capaz de predecir mediante simulaciones, y con alta precisión, las tensiones que deben introducirse en cada celda teniendo en cuenta su ángulo de incidencia, sus dimensiones, la frecuencia, así como la señal de polarización definida por su frecuencia y forma de onda AC. Esta estrategia se basa en modelar cada uno de los estados de permitividad del cristal líquido como un sustrato anisótropo con inhomogeneidad longitudinal (1D), o en ciertos casos, como un tensor equivalente homogéneo. La precisión de ambos modelos electromagnéticos también se discute. Con el objetivo de obtener una herramienta eficiente de cálculo de tensiones, también se ha escrito e implementado una herramienta de análisis basada en el Método de los Momentos en el Dominio Espectral (SD-MoM) para sustratos estratificados anisótropos, que se usa en cada iteración del procedimiento de síntesis para analizar cada una de las celdas de la antena. La síntesis de tensiones se ha diseñado además para reducir al máximo el efecto del rizado de amplitud en el diagrama de radiación, que es característico en los reflectarrays que están formados por celdas con pérdidas elevadas, lo que en sí, supone un avance adicional para la obtención de mejores prestaciones de antena. Para el cálculo de los diagramas de radiación empleados en el procedimiento de síntesis, se asume un análisis elemento a elemento considerando periodicidad local, y se propone el uso de un método capaz de modelar el campo incidente de forma que se elimine la limitación de la periodicidad local en la excitación. Una vez definida la estrategia adecuada de cálculo de las tensiones a aplicar al cristal líquido en cada celda, la estructura de direccionamiento de las mismas en la antena, y diseñados los circuitos de control, se diseñan, fabrican y miden dos prototipos diferentes de antena de barrido electrónico a 100 GHz usando las celdas anteriormente presentadas. El primero de estos prototipos es un reflectarray en configuración “single offset” con capacidad de escaneo en un plano (elevación o azimut). Aunque previamente se realizan diseños de antenas de barrido en 2D a varias frecuencias en el rango de milimétricas y sub-milimétricas, y se proponen ciertas estrategias de direccionamiento que permiten conseguir este objetivo, se desarrolla el prototipo con direccionamiento en una dimensión con el fin de reducir el número de controles y posibles errores de fabricación, y así también validar la herramienta de diseño. Para un tamaño medio de apertura (con un numero de filas y columnas entre 30 y 50 elementos, lo que significa un reflectarray con un número de elementos superior a 900), la configuración “single offset” proporciona rangos de escaneo elevados, y ganancias que pueden oscilar entre los 20 y 30 dBi. En concreto, el prototipo medido proporciona un haz de barrido en un rango angular de 55º, en el que el nivel de lóbulos secundarios (SLL) permanece mejor de -13 dB en un ancho de banda de un 8%. La ganancia máxima es de 19.4 dBi. Estas prestaciones superan de forma clara aquellas conseguidas por otros autores. El segundo prototipo se corresponde con una antena de doble reflector que usa el reflectarray de cristal líquido como sub-reflector para escanear el haz en un plano (elevación o azimut). El objetivo básico de esta geometría es obtener mayores ganancias que en el reflectarray “single offset” con una estructura más compacta, aunque a expensas de reducir el rango de barrido. En concreto, se obtiene una ganancia máxima de 35 dBi, y un rango de barrido de 12º. Los procedimientos de síntesis de tensiones y de diseño de las estructuras de las celdas forman, en su conjunto, una herramienta completa de diseño precisa y eficiente de antenas reflectarray reconfigurables basados en cristales líquidos. Dicha herramienta se ha validado mediante el diseño, la fabricación y la medida de los prototipos anteriormente citados a 100 GHz, que consiguen algo nunca alcanzado anteriormente en la investigación de este tipo de antenas: unas prestaciones competitivas y una predicción excelente de los resultados. El procedimiento es general, y por tanto se puede usar a cualquier frecuencia en la que el cristal líquido ofrezca anisotropía dieléctrica, incluidos los THz. Los prototipos desarrollados en esta tesis doctoral suponen también unas de las primeras antenas de barrido real a frecuencias superiores a 100 GHz. En concreto, la antena de doble reflector para escaneo de haz es la primera antena reconfigurable electrónicamente a frecuencias superiores a 60 GHz que superan los 25 dBi de ganancia, siendo a su vez la primera antena de doble reflector que contiene un reflectarray reconfigurable como sub-reflector. Finalmente, se proponen ciertas mejoras que aún deben se deben realizar para hacer que estas antenas puedan ser un producto completamente desarrollado y competitivo en el mercado. ABSTRACT The work presented in this thesis is focused on the development of electronically reconfigurable antennas that are able to provide competitive electrical performance to the increasingly common applications operating at frequencies above 60 GHz. Specifically, this thesis presents the study, design, and implementation of reflectarray antennas, which incorporate liquid crystal (LC) materials to scan or reconfigure the beam electronically. From a general point of view, a liquid crystal can be defined as a material whose dielectric permittivity is variable and can be controlled with an external excitation, which usually corresponds with a quasi-static electric field (AC). By changing the dielectric permittivity at each cell that makes up the reflectarray, the phase shift on the aperture is controlled, so that a prescribed radiation pattern can be configured. Liquid Crystal-based reflectarrays have been chosen for several reasons. The first has to do with the advantages provided by the reflectarray antenna with respect to other high gain antennas, such as reflectors or phased arrays. The RF feeding in reflectarrays is achieved by using a common primary source (as in reflectors). This arrangement and the large number of degrees of freedom provided by the cells that make up the reflectarray (as in arrays), allow these antennas to provide a similar or even better electrical performance than other low profile antennas (reflectors and arrays), but assuming a more reduced cost and compactness. The second reason is the flexibility of the liquid crystal to be confined in an arbitrary geometry due to its fluidity (property of liquids). Therefore, the liquid crystal is able to adapt to a planar geometry so that it is one or more of the typical layers of this configuration. This simplifies drastically both the structure and manufacture of this type of antenna, even when compared with reconfigurable reflectarrays based on other technologies, such as diodes MEMS, etc. Therefore, the cost of developing this type of antenna is very small, which means that electrically large reconfigurable reflectarrays could be manufactured assuming low cost and greater productions. A paradigmatic example of a similar structure is the liquid crystal panel, which has already been commercialized successfully. The third reason lies in the fact that, at present, the liquid crystal is one of the few technologies capable of providing switching capabilities at frequencies above 60 GHz. In fact, the liquid crystal allows its permittivity to be switched in a wide range of frequencies, which are from DC to the visible spectrum, including microwaves and THz. Other technologies, such as ferroelectric materials, graphene or CMOS "on chip" technology also allow the beam to be switched at these frequencies. However, CMOS technology is expensive and is currently limited to frequencies below 150 GHz, and although ferroelectric materials or graphene can switch at higher frequencies and in a wider range, they have serious difficulties that make them immature. Ferroelectric materials involve the use of very high voltages to switch the material, making them unattractive, whereas the electromagnetic modelling of the graphene is still under discussion, so that the experimental results of devices based on this latter technology have not been reported yet. These three reasons make LC-based reflectarrays attractive for many applications that involve the use of electronically reconfigurable beams at frequencies beyond 60 GHz. Applications such as high resolution imaging radars, molecular spectroscopy, radiometers for atmospheric observation, or high frequency wireless communications (WiGig) are just some of them. This thesis is divided into three parts. In the first part, the most common properties of the liquid crystal materials are described, especially those exhibited in the nematic phase. The study is focused on the dielectric anisotropy (Ac) of uniaxial liquid crystals, which is defined as the difference between the parallel (e/7) and perpendicular (e±) permittivities: Ae = e,, - e±. This parameter allows the permittivity of a LC confined in an arbitrary volume at a certain biasing voltage to be described by solving a variational problem that involves both the electrostatic and elastic energies. Thus, the frequency dependence of (Ae) is also described and characterised. Note that an appropriate LC modelling is quite important to ensure enough accuracy in the phase shift provided by each cell that makes up the reflectarray, and therefore to achieve a good electrical performance at the antenna level. The second part of the thesis is focused on the design of resonant reflectarray cells based on liquid crystal. The reason why resonant cells have been chosen lies in the fact that they are able to provide enough phase range using the values of the dielectric anisotropy of the liquid crystals, which are typically small. Thus, the aim of this part is to investigate several reflectarray cell architectures capable of providing good electrical performance at the antenna level, which significantly improve the electrical performance of the cells reported in the literature. Similarly, another of the objectives is to develop a general tool to design these cells. To fulfill these objectives, the electrical yields of different types of resonant reflectarray elements are investigated, beginning from the simplest, which is made up of a single resonator and limits the state of the art. To overcome the electrical limitations of the single resonant cell, several elements consisting of multiple resonators are considered, which can be single-layer or multilayer. In a first step, the design procedure of these structures makes use of a conventional electromagnetic model which has been used in the literature, which considers that the liquid crystal behaves as homogeneous and isotropic materials whose permittivity varies between (e/7) y (e±). However, in this part of the thesis it is shown that the conventional modelling is not enough to describe the physical behaviour of the liquid crystal in reflectarray cells accurately. Therefore, a more accurate analysis and design procedure based on a more general model is proposed and developed, which defines the liquid crystal as an anisotropic three-dimensional inhomogeneous material. The design procedure is able to optimize multi-resonant cells efficiently to achieve good electrical performance in terms of bandwidth, phase range, losses, or sensitivity to the angle of incidence. The errors made when the conventional modelling (amplitude and phase) is considered have been also analysed for various cell geometries, by using measured results from several antenna prototypes made up of real liquid crystals at frequencies above 100 GHz. The measurements have been performed in a periodic environment using a quasi-optical bench, which has been designed especially for this purpose. One of these prototypes has been optimized to achieve a relatively large bandwidth (10%) at 100 GHz, low losses, a phase range of more than 360º, a low sensitivity to angle of incidence, and a low influence of the transversal inhomogeneity of the liquid crystal in the cell. The electrical yields of this prototype at the cell level improve those achieved by other elements reported in the literature, so that this prototype has been used in the last part of the thesis to perform several complete antennas for beam scanning applications. Finally, in this second part of the thesis, a novel strategy to characterise the macroscopic anisotropy using reflectarray cells is presented. The results in both RF and AC frequencies are compared with those obtained by other methods. The third part of the thesis consists on the study, design, manufacture and testing of LCbased reflectarray antennas in complex configurations. Note that the design procedure of a passive reflectarray antenna just consists on finding out the dimensions of the metallisations of each cell (which are used for phase control), using well-known optimization processes. However, in the case of reconfigurable reflectarrays based on liquid crystals, an additional step must be taken into account, which consists of accurately calculating the control voltages to be applied to each cell to configure the required phase-shift distribution on the surface of the antenna. Similarly, the structure to address the voltages at each cell and the control circuitry must be also considered. Therefore, the voltage synthesis is even more important than the design of the cell geometries (dimensions), since the voltages are directly related to the phase-shift. Several voltage synthesis procedures have been proposed in the state of the art, which are based on the experimental characterization of the phase/voltage curve. However, this characterization can be only carried out at a single angle of incidence and at certain cell dimensions, so that the synthesized voltages are different from those needed, thus giving rise to phase errors of more than 70°. Thus, the electrical yields of the LCreflectarrays reported in the literature are limited in terms of bandwidth, scanning range or side lobes level. In this last part of the thesis, a new voltage synthesis procedure has been defined and developed, which allows the required voltage to be calculated at each cell using simulations that take into account the particular dimensions of the cells, their angles of incidence, the frequency, and the AC biasing signal (frequency and waveform). The strategy is based on the modelling of each one of the permittivity states of the liquid crystal as an anisotropic substrate with longitudinal inhomogeneity (1D), or in certain cases, as an equivalent homogeneous tensor. The accuracy of both electromagnetic models is also discussed. The phase errors made by using the proposed voltage synthesis are better than 7º. In order to obtain an efficient tool to analyse and design the reflectarray, an electromagnetic analysis tool based on the Method of Moments in the spectral domain (SD-MoM) has also written and developed for anisotropic stratified media, which is used at each iteration of the voltage synthesis procedure. The voltage synthesis is also designed to minimize the effect of amplitude ripple on the radiation pattern, which is typical of reflectarrays made up of cells exhibiting high losses and represents a further advance in achieving a better antenna performance. To calculate the radiation patterns used in the synthesis procedure, an element-by-element analysis is assumed, which considers the local periodicity approach. Under this consideration, the use of a novel method is proposed, which avoids the limitation that the local periodicity imposes on the excitation. Once the appropriate strategy to calculate the voltages to be applied at each cell is developed, and once it is designed and manufactured both the structure to address the voltages to the antenna and the control circuits, two complete LC-based reflectarray antennas that operate at 100 GHz have been designed, manufactured and tested using the previously presented cells. The first prototype consists of a single offset reflectarray with beam scanning capabilities on one plane (elevation and azimuth). Although several LC-reflectarray antennas that provide 2-D scanning capabilities are also designed, and certain strategies to achieve the 2-D addressing of the voltage are proposed, the manufactured prototype addresses the voltages in one dimension in order to reduce the number of controls and manufacturing errors, and thereby validating the design tool. For an average aperture size (with a number of rows and columns of between 30 and 50 elements, which means a reflectarray with more than 900 cells), the single offset configuration provides an antenna gain of between 20 and 30 dBi and a large scanning range. The prototype tested at 100 GHz exhibits an electronically scanned beam in an angular range of 55º and 8% of bandwidth, in which the side lobe level (SLL) remains better than -13 dB. The maximum gain is 19.4 dBi. The electrical performance of the antenna is clearly an improvement on those achieved by other authors in the state of the art. The second prototype corresponds to a dual reflector antenna with a liquid crystal-based reflectarray used as a sub-reflector for beam scanning in one plane (azimuth or elevation). The main objective is to obtain a higher gain than that provided by the single offset configuration, but using a more compact architecture. In this case, a maximum gain of 35 dBi is achieved, although at the expense of reducing the scanning range to 12°, which is inherent in this type of structure. As a general statement, the voltage synthesis and the design procedure of the cells, jointly make up a complete, accurate and efficient design tool of reconfigurable reflectarray antennas based on liquid crystals. The tool has been validated by testing the previously mentioned prototypes at 100 GHz, which achieve something never reached before for this type of antenna: a competitive electrical performance, and an excellent prediction of the results. The design procedure is general and therefore can be used at any frequency for which the liquid crystal exhibits dielectric anisotropy. The two prototypes designed, manufactured and tested in this thesis are also some of the first antennas that currently operate at frequencies above 100 GHz. In fact, the dual reflector antenna is the first electronically scanned dual reflector antenna at frequencies above 60 GHz (the operation frequency is 100 GHz) with a gain greater than 25 dBi, being in turn the first dual-reflector antenna with a real reconfigurable sub-reflectarray. Finally, some improvements that should be still investigated to make these antennas commercially competitive are proposed.