Entorno histórico y social de la aparición del microchip

El siguiente proyecto es un desarrollo histórico-científico acerca de la notoria importancia que supuso la aparición del microchip o circuito integrado1. El desarrollo de este trabajo ha sido una investigación bibliográfica en contenidos webs, enciclopedias y libros. El trabajo contiene un estudio sobre los transistores que fue el componente que dio paso al circuito integrado además de ser uno de los mayores inventos del siglo XX, además, se propone una pequeña inmersión a la época histórica del momento de la aparición del transistor. Al igual que con el transistor, se hace un estudio acerca del circuito integrado, pero en este caso siendo más extenso ya que es el objeto de estudio de este PFC. Para este componente sí que podemos encontrar una explicación más exhaustiva acerca de su fabricación, materiales. Además también podemos encontrar el momento históricosocial de la época bajo estudio. Para finalizar con el proyecto, se hace un breve repaso de los ejemplos de aplicación del circuito integrado y así poder hacer hincapié de la revolución tecnológica que supuso el descubrimiento del microchip. ABSTRACT. The following work is a historical and scientific development regarding the fundamental importance the emergence of the microchip. The development of this work has consisted of a bibliographic research of web contents, encyclopedias and books. The paper contains a study about the transistors, component that propitiated the integrated circuit and was one of the most important inventions of the XXth century. Also is proposed a short historical immersion in the time that preceded the coming of the transistor. As well as with the transistor, a study of the integrated circuit is carried out, yet with deeper insight, for that is the central aim of this Final Project report. For this component a more exhaustive explanation of its manufacture process, materials and theories can be provided. Also, the historical and social of that time is described. To complete the report, a brief review is done about examples of applications of the integrated circuit and thus highlight the technological revolution that the microchip development brought.

Technical note: Comparison of automated ribosomal intergenic spacer analysis (ARISA) and denaturing gradient gel electrophoresis (DGGE) to assess bacterial diversity in the rumen of sheep

The aim of this study was to compare automated ribosomal intergenic spacer analysis (ARISA) and denaturing gradient gel electrophoresis (DGGE) techniques to assess bacterial diversity in the rumen of sheep. Sheep were fed 2 diets with 70% of either alfalfa hay or grass hay, and the solid (SOL) and liquid (LIQ) phases of the rumen were sampled immediately before feeding (0 h) and at 4 and 8 h postfeeding. Both techniques detected similar differences between forages, with alfalfa hay promoting greater (P < 0.05) bacterial diversity than grass hay. In contrast, whereas ARISA analysis showed a decrease (P < 0.05) of bacterial diversity in SOL at 4 h postfeeding compared with 0 and 8 h samplings, no variations (P > 0.05) over the postfeeding period were detected by DGGE. The ARISA technique showed lower (P < 0.05) bacterial diversity in SOL than in LIQ samples at 4 h postfeeding, but no differences (P > 0.05) in bacterial diversity between both rumen phases were detected by DGGE. Under the conditions of this study, the DGGE was not sensitive enough to detect some changes in ruminal bacterial communities, and therefore ARISA was considered more accurate for assessing bacterial diversity of ruminal samples. The results highlight the influence of the fingerprinting technique used to draw conclusions on factors affecting ruminal bacterial diversity.