62 resultados para Mucopolissacaridose tipo 1
Resumo:
La valoración de inmuebles urbanos y más cuando se afronta desde un punto de vista masivo, no es una actividad sencilla. Tanto la legislación vigente en España como los estándares de valoración internacionales establecen que los valores deben de estar referenciados al valor de mercado, pero el mercado inmobiliario se caracteriza por su limitada transparencia y porque el producto es relativamente ilíquido. En este contexto, parece necesario acometer el estudio de nuevas herramientas que faciliten el establecer con mayor seguridad el valor de los inmuebles. El análisis de los factores que determinan el precio de los inmuebles permite identificar aquellas características que más inciden en el mismo, como son su tamaño, uso, tipología, calidad, antigüedad y localización. A partir de ellas y a través del estudio de la estructura urbana, localizando las zonas homogéneas y analizando las variables de su producto inmobiliario, se ha desarrollado una nueva metodología basada en el tipo edificatorio como estrategia para la valoración territorial. A lo largo de este trabajo, cuyo ámbito de análisis se ha centrado en los municipios de la Comunidad de Madrid, mediante el análisis comparado de sus características, se va a exponer cómo el tipo de estructura urbana influye significativamente en la calidad de los resultados que se obtienen. También se va a incidir en la sensibilidad de los mismos a los diferentes métodos de tratamiento de datos y de análisis matemático y estadístico. Con todo, se puede afirmar que la utilización de la metodología que se propone facilita, mejora y apoya la valoración de inmuebles, siendo posible su aplicación directa tanto para la valoración masiva de inmuebles como en la individualizada. ABSTRACT The valuation of urban property and more so when one is confronted with it from a massive point of view, is not an easy task. Taking into consideration Spain‟s current regulations as well as the international valuation standards, they establish that the values must be referred to the market value, but the real-estate market is characterised by its limited transparency and because the product is relatively illiquid. Under these circumstances, it seems necessary to undertake the study of new tools that facilitate the obtention of more accurate and secure valuation of real estate assets. The analysis of the factors that determine the price of property allow us to identify those characteristics that influence it most, such as size, use, typology, quality, age and location. Taking these points into consideration and through the study of urban structure, localising the homogeneous areas and analysing the variables of its real-estate product, a new methodology has been developed based on the type of building as well as on the local valuation strategy. Throughout this work, whose scope of analysis has been focussed on the municipalities of the Autonomous Region of Madrid through a comparative analysis of its characteristics, it will be shown how the type of urban structure can significantly influence the quality of the results that are obtained. It will also affect their sensitivity to the different methods of data processing, and of mathematical and statistical analysis. In all, one can confirm that using the methodology that is being proposed facilitates, improves and supports the valuation of properties, enabling its direct application for the mass valuation of property as well as for the individual one.
Resumo:
Four rumen-fistulated sheep fed a 66:34 alfalfa hay:concentrate diet were used as donors to investigate the effect of rumen contents’ treatment on microbial populations in the resulting fluid. Rumen contents were sampled from each individual sheep and subjected to the following treatments: SQ: squeezed through 4 layers of cheesecloth; FIL: SQ treatment and further filtration through a 100-μm nylon cloth; STO: reated with a Stomacher® for 3 min at 230 rev min-1 and followed by SQ. Microbial populations in the fluid were analysed by real-time PCR and bacterial diversity was assessed by the automated ribosomal intergenic spacer analysis (ARISA) of the 16S ribosomal DNA. Bacterial DNA concentrations and relative abundance of Ruminococcus flavefaciens, arqueal and fungal DNA did not differ (P>0.05) between treatments. In contrast, STO treatment decreased (P<0.05) protozoal DNA concentrations and increased (P<0.05) the relative abundance of Fibrobacter succinogenes compared with SQ method. There were no differences (P>0.05) between treatments either in the Shannon index or in the number of peaks in the ARISA electropherograms, indicating no effect on bacterial diversity. Studies analyzing the influence on the tested methods on fermentation characteristics of different substrates when the fluid is used as inoculum is required.