3D Wavelet-based Fusion Techniques for Biomedical Imaging

Hoy en día las técnicas de adquisición de imágenes tridimensionales son comunes en diversas áreas, pero cabe destacar la relevancia que han adquirido en el ámbito de la imagen biomédica, dentro del cual encontramos una amplia gama de técnicas como la microscopía confocal, microscopía de dos fotones, microscopía de fluorescencia mediante lámina de luz, resonancia magnética nuclear, tomografía por emisión de positrones, tomografía de coherencia óptica, ecografía 3D y un largo etcétera. Un denominador común de todas esas aplicaciones es la constante necesidad por aumentar la resolución y la calidad de las imágenes adquiridas. En algunas de dichas técnicas de imagen tridimensional se da una interesante situación: aunque que cada volumen adquirido no contiene información suficiente para representar el objeto bajo estudio dentro de los parámetros de calidad requeridos por algunas aplicaciones finales, el esquema de adquisición permite la obtención de varios volúmenes que representan diferentes vistas de dicho objeto, de tal forma que cada una de las vistas proporciona información complementaria acerca del mismo. En este tipo de situación es posible, mediante la combinación de varias de esas vistas, obtener una mejor comprensión del objeto que a partir de cada una de ellas por separado. En el contexto de esta Tesis Doctoral se ha propuesto, desarrollado y validado una nueva metodología de proceso de imágenes basada en la transformada wavelet disc¬reta para la combinación, o fusión, de varias vistas con información complementaria de un mismo objeto. El método de fusión propuesto aprovecha la capacidad de descom¬posición en escalas y orientaciones de la transformada wavelet discreta para integrar en un solo volumen toda la información distribuida entre el conjunto de vistas adquiridas. El trabajo se centra en dos modalidades diferentes de imagen biomédica que per¬miten obtener tales adquisiciones multi-vista. La primera es una variante de la micro¬scopía de fluorescencia, la microscopía de fluorescencia mediante lámina de luz, que se utiliza para el estudio del desarrollo temprano de embriones vivos en diferentes modelos animales, como el pez cebra o el erizo de mar. La segunda modalidad es la resonancia magnética nuclear con realce tardío, que constituye una valiosa herramienta para evaluar la viabilidad del tejido miocárdico en pacientes con diversas miocardiopatías. Como parte de este trabajo, el método propuesto ha sido aplicado y validado en am¬bas modalidades de imagen. En el caso de la aplicación a microscopía de fluorescencia, los resultados de la fusión muestran un mejor contraste y nivel de detalle en comparación con cualquiera de las vistas individuales y el método no requiere de conocimiento previo acerca la función de dispersión puntual del sistema de imagen. Además, los resultados se han comparado con otros métodos existentes. Con respecto a la aplicación a imagen de resonancia magnética con realce tardío, los volúmenes fusionados resultantes pre-sentan una mejora cuantitativa en la nitidez de las estructuras relevantes y permiten una interpretación más sencilla y completa de la compleja estructura tridimensional del tejido miocárdico en pacientes con cardiopatía isquémica. Para ambas aplicaciones los resultados de esta tesis se encuentran actualmente en uso en los centros clínicos y de investigación con los que el autor ha colaborado durante este trabajo. Además se ha puesto a libre disposición de la comunidad científica la implementación del método de fusión propuesto. Por último, se ha tramitado también una solicitud de patente internacional que cubre el método de visualización desarrollado para la aplicación de Resonancia Magnética Nuclear. Abstract Nowadays three dimensional imaging techniques are common in several fields, but es-pecially in biomedical imaging, where we can find a wide range of techniques including: Laser Scanning Confocal Microscopy, Laser Scanning Two Photon Microscopy, Light Sheet Fluorescence Microscopy, Magnetic Resonance Imaging, Positron Emission To-mography, Optical Coherence Tomography, 3D Ultrasound Imaging, etc. A common denominator of all those applications being the constant need for further increasing resolution and quality of the acquired images. Interestingly, in some of the mentioned three-dimensional imaging techniques a remarkable situation arises: while a single volume does not contain enough information to represent the object being imaged within the quality parameters required by the final application, the acquisition scheme allows recording several volumes which represent different views of a given object, with each of the views providing complementary information. In this kind of situation one can get a better understanding of the object by combining several views instead of looking at each of them separately. Within such context, in this PhD Thesis we propose, develop and test new image processing methodologies based on the discrete wavelet transform for the combination, or fusion, of several views containing complementary information of a given object. The proposed fusion method exploits the scale and orientation decomposition capabil¬ities of the discrete wavelet transform to integrate in a single volume all the available information distributed among the set of acquired views. The work focuses in two different biomedical imaging modalities which provide such multi-view datasets. The first one is a particular fluorescence microscopy technique, Light-Sheet Fluorescence Microscopy, used for imaging and gaining understanding of the early development of live embryos from different animal models (like zebrafish or sea urchin). The second is Delayed Enhancement Magnetic Resonance Imaging, which is a valuable tool for assessing the viability of myocardial tissue on patients suffering from different cardiomyopathies. As part of this work, the proposed method was implemented and then validated on both imaging modalities. For the fluorescence microscopy application, the fusion results show improved contrast and detail discrimination when compared to any of the individual views and the method does not rely on prior knowledge of the system’s point spread function (PSF). Moreover, the results have shown improved performance with respect to previous PSF independent methods. With respect to its application to Delayed Enhancement Magnetic Resonance Imaging, the resulting fused volumes show a quantitative sharpness improvement and enable an easier and more complete interpretation of complex three-dimensional scar and heterogeneous tissue information in ischemic cardiomyopathy patients. In both applications, the results of this thesis are currently in use in the clinical and research centers with which the author collaborated during his work. An imple¬mentation of the fusion method has also been made freely available to the scientific community. Finally, an international patent application has been filed covering the visualization method developed for the Magnetic Resonance Imaging application.

A proposal for a flexible scheduling and memory management scheme for non-deterministic, andparallel execution of logic programs

In this paper, we examine the issue of memory management in the parallel execution of logic programs. We concentrate on non-deterministic and-parallel schemes which we believe present a relatively general set of problems to be solved, including most of those encountered in the memory management of or-parallel systems. We present a distributed stack memory management model which allows flexible scheduling of goals. Previously proposed models (based on the "Marker model") are lacking in that they impose restrictions on the selection of goals to be executed or they may require consume a large amount of virtual memory. This paper first presents results which imply that the above mentioned shortcomings can have significant performance impacts. An extension of the Marker Model is then proposed which allows flexible scheduling of goals while keeping (virtual) memory consumption down. Measurements are presented which show the advantage of this solution. Methods for handling forward and backward execution, cut and roll back are discussed in the context of the proposed scheme. In addition, the paper shows how the same mechanism for flexible scheduling can be applied to allow the efficient handling of the very general form of suspension that can occur in systems which combine several types of and-parallelism and more sophisticated methods of executing logic programs. We believe that the results are applicable to many and- and or-parallel systems.

The direct boundary element method: 2D site effects assessment on laterally varying layered media (methodology)

The Direct Boundary Element Method (DBEM) is presented to solve the elastodynamic field equations in 2D, and a complete comprehensive implementation is given. The DBEM is a useful approach to obtain reliable numerical estimates of site effects on seismic ground motion due to irregular geological configurations, both of layering and topography. The method is based on the discretization of the classical Somigliana's elastodynamic representation equation which stems from the reciprocity theorem. This equation is given in terms of the Green's function which is the full-space harmonic steady-state fundamental solution. The formulation permits the treatment of viscoelastic media, therefore site models with intrinsic attenuation can be examined. By means of this approach, the calculation of 2D scattering of seismic waves, due to the incidence of P and SV waves on irregular topographical profiles is performed. Sites such as, canyons, mountains and valleys in irregular multilayered media are computed to test the technique. The obtained transfer functions show excellent agreement with already published results.

An optimized QoS scheme for IMS-NEMO in heterogeneous networks

The network mobility (NEMO) is proposed to support the mobility management when users move as a whole. In IP Multimedia Subsystem (IMS), the individual Quality of Service (QoS) control for NEMO results in excessive signaling cost. On the other hand, current QoS schemes have two drawbacks: unawareness of the heterogeneous wireless environment and inefficient utilization of the reserved bandwidth. To solve these problems, we present a novel heterogeneous bandwidth sharing (HBS) scheme for QoS provision under IMS-based NEMO (IMS-NEMO). The HBS scheme selects the most suitable access network for each session and enables the new coming non-real-time sessions to share bandwidth with the Variable Bit Rate (VBR) coded media flows. The modeling and simulation results demonstrate that the HBS can satisfy users' QoS requirement and obtain a more efficient use of the scarce wireless bandwidth.

Novel system for bite-force sensing and monitoring based on magnetic eear field communication

Intraoral devices for bite-force sensing have several applications in odontology and maxillofacial surgery, as bite-force measurements provide additional information to help understand the characteristics of bruxism disorders and can also be of help for the evaluation of post-surgical evolution and for comparison of alternative treatments. A new system for measuring human bite forces is proposed in this work. This system has future applications for the monitoring of bruxism events and as a complement for its conventional diagnosis. Bruxism is a pathology consisting of grinding or tight clenching of the upper and lower teeth, which leads to several problems such as lesions to the teeth, headaches, orofacial pain and important disorders of the temporomandibular joint. The prototype uses a magnetic field communication scheme similar to low-frequency radio frequency identification (RFID) technology (NFC). The reader generates a low-frequency magnetic field that is used as the information carrier and powers the sensor. The system is notable because it uses an intra-mouth passive sensor and an external interrogator, which remotely records and processes information regarding a patient?s dental activity. This permits a quantitative assessment of bite-force, without requiring intra-mouth batteries, and can provide supplementary information to polysomnographic recordings, current most adequate early diagnostic method, so as to initiate corrective actions before irreversible dental wear appears. In addition to describing the system?s operational principles and the manufacture of personalized prototypes, this report will also demonstrate the feasibility of the system and results from the first in vitro and in vivo trials.

An attitude-based reasoning strategy to enhance interaction with augmented objects

This paper describes a mobile-based system to interact with objects in smart spaces, where the offer of resources may be extensive. The underlying idea is to use the augmentation capabilities of the mobile device to enable it as user-object mediator. In particular, the paper details how to build an attitude-based reasoning strategy that facilitates user-object interaction and resource filtering. The strategy prioritizes the available resources depending on the spatial history of the user, his real-time location and orientation and, finally, his active touch and focus interactions with the virtual overlay. The proposed reasoning method has been partially validated through a prototype that handles 2D and 3D visualization interfaces. This framework makes possible to develop in practice the IoT paradigm, augmenting the objects without physically modifying them.

Authentication in mobile devices through hand gesture recognition

This article proposes an innovative biometric technique based on the idea of authenticating a person on a mobile device by gesture recognition. To accomplish this aim, a user is prompted to be recognized by a gesture he/she performs moving his/her hand while holding a mobile device with an accelerometer embedded. As users are not able to repeat a gesture exactly in the air, an algorithm based on sequence alignment is developed to correct slight differences between repetitions of the same gesture. The robustness of this biometric technique has been studied within 2 different tests analyzing a database of 100 users with real falsifications. Equal Error Rates of 2.01 and 4.82% have been obtained in a zero-effort and an active impostor attack, respectively. A permanence evaluation is also presented from the analysis of the repetition of the gestures of 25 users in 10 sessions over a month. Furthermore, two different gesture databases have been developed: one made up of 100 genuine identifying 3-D hand gestures and 3 impostors trying to falsify each of them and another with 25 volunteers repeating their identifying 3- D hand gesture in 10 sessions over a month. These databases are the most extensive in published studies, to the best of our knowledge.

Improving Hardware Reuse through XML-based Interface Encapsulation

This work proposes an encapsulation scheme aimed at simplifying the reuse process of hardware cores. This hardware encapsulation approach has been conceived with a twofold objective. First, we look for the improvement of the reuse interface associated with the hardware core description. This is carried out in a first encapsulation level by improving the limited types and configuration options available in the conventional HDLs interface, and also providing information related to the implementation itself. Second, we have devised a more generic interface focused on describing the function avoiding details from a particular implementation, what corresponds to a second encapsulation level. This encapsulation allows the designer to define how to configure and use the design to implement a given functionality. The proposed encapsulation schemes help improving the amount of information that can be supplied with the design, and also allow to automate the process of searching, configuring and implementing diverse alternatives.

Smart parking service based on wireless sensor networks

n this paper, we present the design and implementation of a prototype system of Smart Parking Services based on Wireless Sensor Networks (WSNs) that allows vehicle drivers to effectively find the free parking places. The proposed scheme consists of wireless sensor networks, embedded web-server, central web-server and mobile phone application. In the system, low-cost wireless sensors networks modules are deployed into each parking slot equipped with one sensor node. The state of the parking slot is detected by sensor node and is reported periodically to embedded web-server via the deployed wireless sensor networks. This information is sent to central web-server using Wi-Fi networks in real-time, and also the vehicle driver can find vacant parking lots using standard mobile devices.

VISIONS Vehicular communication Improvement : solution based on IMS Operational Nodes and Services

Digital services and communications in vehicular scenarios provide the essential assets to improve road transport in several ways like reducing accidents, improving traffic efficiency and optimizing the transport of goods and people. Vehicular communications typically rely on VANET (Vehicular Ad hoc Networks). In these networks vehicles communicate with each other without the need of infrastructure. VANET are mainly oriented to disseminate information to the vehicles in certain geographic area for time critical services like safety warnings but present very challenging requirements that have not been successfully fulfilled nowadays. Some of these challenges are; channel saturation due to simultaneous radio access of many vehicles, routing protocols in topologies that vary rapidly, minimum quality of service assurance and security mechanisms to efficiently detect and neutralize malicious attacks. Vehicular services can be classified in four important groups: Safety, Efficiency, Sustainability and Infotainment. The benefits of these services for the transport sector are clear but many technological and business challenges need to be faced before a real mass market deployment. Service delivery platforms are not prepared for fulfilling the needs of this complex environment with restrictive requirements due to the criticism of some services To overcome this situation, we propose a solution called VISIONS “Vehicular communication Improvement: Solution based on IMS Operational Nodes and Services”. VISIONS leverages on IMS subsystem and NGN enablers, and follows the CALM reference Architecture standardized by ISO. It also avoids the use of Road Side Units (RSUs), reducing complexity and high costs in terms of deployment and maintenance. We demonstrate the benefits in the following areas: 1. VANET networks efficiency. VISIONS provide a mechanism for the vehicles to access valuable information from IMS and its capabilities through a cellular channel. This efficiency improvement will occur in two relevant areas: a. Routing mechanisms. These protocols are responsible of carrying information from a vehicle to another (or a group of vehicles) using multihop mechanisms. We do not propose a new algorithm but the use of VANET topology information provided through our solution to enrich the performance of these protocols. b. Security. Many aspects of security (privacy, key, authentication, access control, revocation mechanisms, etc) are not resolved in vehicular communications. Our solution efficiently disseminates revocation information to neutralize malicious nodes in the VANET. 2. Service delivery platform. It is based on extended enablers, reference architectures, standard protocols and open APIs. By following this approach, we reduce costs and resources for service development, deployment and maintenance. To quantify these benefits in VANET networks, we provide an analytical model of the system and simulate our solution in realistic scenarios. The simulations results demonstrate how VISIONS improves the performance of relevant routing protocols and is more efficient neutralizing security attacks than the widely proposed solutions based on RSUs. Finally, we design an innovative Social Network service based in our platform, explaining how VISIONS facilitate the deployment and usage of complex capabilities. RESUMEN Los servicios digitales y comunicaciones en entornos vehiculares proporcionan herramientas esenciales para mejorar el transporte por carretera; reduciendo el número de accidentes, mejorando la eficiencia del tráfico y optimizando el transporte de mercancías y personas. Las comunicaciones vehiculares generalmente están basadas en redes VANET (Vehicular Ad hoc Networks). En dichas redes, los vehículos se comunican entre sí sin necesidad de infraestructura. Las redes VANET están principalmente orientadas a difundir información (por ejemplo advertencias de seguridad) a los vehículos en determinadas zonas geográficas, pero presentan unos requisitos muy exigentes que no se han resuelto con éxito hasta la fecha. Algunos de estos retos son; saturación del canal de acceso de radio debido al acceso simultáneo de múltiples vehículos, la eficiencia de protocolos de encaminamiento en topologías que varían rápidamente, la calidad de servicio (QoS) y los mecanismos de seguridad para detectar y neutralizar los ataques maliciosos de manera eficiente. Los servicios vehiculares pueden clasificarse en cuatro grupos: Seguridad, Eficiencia del tráfico, Sostenibilidad, e Infotainment (información y entretenimiento). Los beneficios de estos servicios para el sector son claros, pero es necesario resolver muchos desafíos tecnológicos y de negocio antes de una implementación real. Las actuales plataformas de despliegue de servicios no están preparadas para satisfacer las necesidades de este complejo entorno con requisitos muy restrictivos debido a la criticidad de algunas aplicaciones. Con el objetivo de mejorar esta situación, proponemos una solución llamada VISIONS “Vehicular communication Improvement: Solution based on IMS Operational Nodes and Services”. VISIONS se basa en el subsistema IMS, las capacidades NGN y es compatible con la arquitectura de referencia CALM estandarizado por ISO para sistemas de transporte. También evita el uso de elementos en las carreteras, conocidos como Road Side Units (RSU), reduciendo la complejidad y los altos costes de despliegue y mantenimiento. A lo largo de la tesis, demostramos los beneficios en las siguientes áreas: 1. Eficiencia en redes VANET. VISIONS proporciona un mecanismo para que los vehículos accedan a información valiosa proporcionada por IMS y sus capacidades a través de un canal de celular. Dicho mecanismo contribuye a la mejora de dos áreas importantes: a. Mecanismos de encaminamiento. Estos protocolos son responsables de llevar información de un vehículo a otro (o a un grupo de vehículos) utilizando múltiples saltos. No proponemos un nuevo algoritmo de encaminamiento, sino el uso de información topológica de la red VANET a través de nuestra solución para enriquecer el funcionamiento de los protocolos más relevantes. b. Seguridad. Muchos aspectos de la seguridad (privacidad, gestión de claves, autenticación, control de acceso, mecanismos de revocación, etc) no están resueltos en las comunicaciones vehiculares. Nuestra solución difunde de manera eficiente la información de revocación para neutralizar los nodos maliciosos en la red. 2. Plataforma de despliegue de servicios. Está basada en capacidades NGN, arquitecturas de referencia, protocolos estándar y APIs abiertos. Siguiendo este enfoque, reducimos costes y optimizamos procesos para el desarrollo, despliegue y mantenimiento de servicios vehiculares. Para cuantificar estos beneficios en las redes VANET, ofrecemos un modelo de analítico del sistema y simulamos nuestra solución en escenarios realistas. Los resultados de las simulaciones muestran cómo VISIONS mejora el rendimiento de los protocolos de encaminamiento relevantes y neutraliza los ataques a la seguridad de forma más eficientes que las soluciones basadas en RSU. Por último, diseñamos un innovador servicio de red social basado en nuestra plataforma, explicando cómo VISIONS facilita el despliegue y el uso de las capacidades NGN.

Radio propagation modeling and measurements for ZigBee based indoor wireless sensor networks

The deployment of nodes in Wireless Sensor Networks (WSNs) arises as one of the biggest challenges of this field, which involves in distributing a large number of embedded systems to fulfill a specific application. The connectivity of WSNs is difficult to estimate due to the irregularity of the physical environment and affects the WSN designers? decision on deploying sensor nodes. Therefore, in this paper, a new method is proposed to enhance the efficiency and accuracy on ZigBee propagation simulation in indoor environments. The method consists of two steps: automatic 3D indoor reconstruction and 3D ray-tracing based radio simulation. The automatic 3D indoor reconstruction employs unattended image classification algorithm and image vectorization algorithm to build the environment database accurately, which also significantly reduces time and efforts spent on non-radio propagation issue. The 3D ray tracing is developed by using kd-tree space division algorithm and a modified polar sweep algorithm, which accelerates the searching of rays over the entire space. Signal propagation model is proposed for the ray tracing engine by considering both the materials of obstacles and the impact of positions along the ray path of radio. Three different WSN deployments are realized in the indoor environment of an office and the results are verified to be accurate. Experimental results also indicate that the proposed method is efficient in pre-simulation strategy and 3D ray searching scheme and is suitable for different indoor environments.

A novel methodology for planning reliable wireless sensor networks

Wireless sensor networks (WSNs) have shown their potentials in various applications, which bring a lot of benefits to users from both research and industrial areas. For many setups, it is envisioned thatWSNs will consist of tens to hundreds of nodes that operate on small batteries. However due to the diversity of the deployed environments and resource constraints on radio communication, sensing ability and energy supply, it is a very challenging issue to plan optimized WSN topology and predict its performance before real deployment. During the network planning phase, the connectivity, coverage, cost, network longevity and service quality should all be considered. Therefore it requires designers coping with comprehensive and interdisciplinary knowledge, including networking, radio engineering, embedded system and so on, in order to efficiently construct a reliable WSN for any specific types of environment. Nowadays there is still a lack of the analysis and experiences to guide WSN designers to efficiently construct WSN topology successfully without many trials. Therefore, simulation is a feasible approach to the quantitative analysis of the performance of wireless sensor networks. However the existing planning algorithms and tools, to some extent, have serious limitations to practically design reliable WSN topology: Only a few of them tackle the 3D deployment issue, and an overwhelming number of works are proposed to place devices in 2D scheme. Without considering the full dimension, the impacts of environment to the performance of WSN are not completely studied, thus the values of evaluated metrics such as connectivity and sensing coverage are not sufficiently accurate to make proper decision. Even fewer planning methods model the sensing coverage and radio propagation by considering the realistic scenario where obstacles exist. Radio signals propagate with multi-path phenomenon in the real world, in which direct paths, reflected paths and diffracted paths contribute to the received signal strength. Besides, obstacles between the path of sensor and objects might block the sensing signals, thus create coverage hole in the application. None of the existing planning algorithms model the network longevity and packet delivery capability properly and practically. They often employ unilateral and unrealistic formulations. The optimization targets are often one-sided in the current works. Without comprehensive evaluation on the important metrics, the performance of planned WSNs can not be reliable and entirely optimized. Modeling of environment is usually time consuming and the cost is very high, while none of the current works figure out any method to model the 3D deployment environment efficiently and accurately. Therefore many researchers are trapped by this issue, and their algorithms can only be evaluated in the same scenario, without the possibility to test the robustness and feasibility for implementations in different environments. In this thesis, we propose a novel planning methodology and an intelligent WSN planning tool to assist WSN designers efficiently planning reliable WSNs. First of all, a new method is proposed to efficiently and automatically model the 3D indoor and outdoor environments. To the best of our knowledge, this is the first time that the advantages of image understanding algorithm are applied to automatically reconstruct 3D outdoor and indoor scenarios for signal propagation and network planning purpose. The experimental results indicate that the proposed methodology is able to accurately recognize different objects from the satellite images of the outdoor target regions and from the scanned floor plan of indoor area. Its mechanism offers users a flexibility to reconstruct different types of environment without any human interaction. Thereby it significantly reduces human efforts, cost and time spent on reconstructing a 3D geographic database and allows WSN designers concentrating on the planning issues. Secondly, an efficient ray-tracing engine is developed to accurately and practically model the radio propagation and sensing signal on the constructed 3D map. The engine contributes on efficiency and accuracy to the estimated results. By using image processing concepts, including the kd-tree space division algorithm and modified polar sweep algorithm, the rays are traced efficiently without detecting all the primitives in the scene. The radio propagation model iv is proposed, which emphasizes not only the materials of obstacles but also their locations along the signal path. The sensing signal of sensor nodes, which is sensitive to the obstacles, is benefit from the ray-tracing algorithm via obstacle detection. The performance of this modelling method is robust and accurate compared with conventional methods, and experimental results imply that this methodology is suitable for both outdoor urban scenes and indoor environments. Moreover, it can be applied to either GSM communication or ZigBee protocol by varying frequency parameter of the radio propagation model. Thirdly, WSN planning method is proposed to tackle the above mentioned challenges and efficiently deploy reliable WSNs. More metrics (connectivity, coverage, cost, lifetime, packet latency and packet drop rate) are modeled more practically compared with other works. Especially 3D ray tracing method is used to model the radio link and sensing signal which are sensitive to the obstruction of obstacles; network routing is constructed by using AODV protocol; the network longevity, packet delay and packet drop rate are obtained via simulating practical events in WSNet simulator, which to the best of our knowledge, is the first time that network simulator is involved in a planning algorithm. Moreover, a multi-objective optimization algorithm is developed to cater for the characteristics of WSNs. The capability of providing multiple optimized solutions simultaneously allows users making their own decisions accordingly, and the results are more comprehensively optimized compared with other state-of-the-art algorithms. iMOST is developed by integrating the introduced algorithms, to assist WSN designers efficiently planning reliable WSNs for different configurations. The abbreviated name iMOST stands for an Intelligent Multi-objective Optimization Sensor network planning Tool. iMOST contributes on: (1) Convenient operation with a user-friendly vision system; (2) Efficient and automatic 3D database reconstruction and fast 3D objects design for both indoor and outdoor environments; (3) It provides multiple multi-objective optimized 3D deployment solutions and allows users to configure the network properties, hence it can adapt to various WSN applications; (4) Deployment solutions in the 3D space and the corresponding evaluated performance are visually presented to users; and (5) The Node Placement Module of iMOST is available online as well as the source code of the other two rebuilt heuristics. Therefore WSN designers will be benefit from v this tool on efficiently constructing environment database, practically and efficiently planning reliable WSNs for both outdoor and indoor applications. With the open source codes, they are also able to compare their developed algorithms with ours to contribute to this academic field. Finally, solid real results are obtained for both indoor and outdoor WSN planning. Deployments have been realized for both indoor and outdoor environments based on the provided planning solutions. The measured results coincide well with the estimated results. The proposed planning algorithm is adaptable according to the WSN designer’s desirability and configuration, and it offers flexibility to plan small and large scale, indoor and outdoor 3D deployments. The thesis is organized in 7 chapters. In Chapter 1, WSN applications and motivations of this work are introduced, the state-of-the-art planning algorithms and tools are reviewed, challenges are stated out and the proposed methodology is briefly introduced. In Chapter 2, the proposed 3D environment reconstruction methodology is introduced and its performance is evaluated for both outdoor and indoor environment. The developed ray-tracing engine and proposed radio propagation modelling method are described in details in Chapter 3, their performances are evaluated in terms of computation efficiency and accuracy. Chapter 4 presents the modelling of important metrics of WSNs and the proposed multi-objective optimization planning algorithm, the performance is compared with the other state-of-the-art planning algorithms. The intelligent WSN planning tool iMOST is described in Chapter 5. RealWSN deployments are prosecuted based on the planned solutions for both indoor and outdoor scenarios, important data are measured and results are analysed in Chapter 6. Chapter 7 concludes the thesis and discusses about future works. vi Resumen en Castellano Las redes de sensores inalámbricas (en inglés Wireless Sensor Networks, WSNs) han demostrado su potencial en diversas aplicaciones que aportan una gran cantidad de beneficios para el campo de la investigación y de la industria. Para muchas configuraciones se prevé que las WSNs consistirán en decenas o cientos de nodos que funcionarán con baterías pequeñas. Sin embargo, debido a la diversidad de los ambientes para desplegar las redes y a las limitaciones de recursos en materia de comunicación de radio, capacidad de detección y suministro de energía, la planificación de la topología de la red y la predicción de su rendimiento es un tema muy difícil de tratar antes de la implementación real. Durante la fase de planificación del despliegue de la red se deben considerar aspectos como la conectividad, la cobertura, el coste, la longevidad de la red y la calidad del servicio. Por lo tanto, requiere de diseñadores con un amplio e interdisciplinario nivel de conocimiento que incluye la creación de redes, la ingeniería de radio y los sistemas embebidos entre otros, con el fin de construir de manera eficiente una WSN confiable para cualquier tipo de entorno. Hoy en día todavía hay una falta de análisis y experiencias que orienten a los diseñadores de WSN para construir las topologías WSN de manera eficiente sin realizar muchas pruebas. Por lo tanto, la simulación es un enfoque viable para el análisis cuantitativo del rendimiento de las redes de sensores inalámbricos. Sin embargo, los algoritmos y herramientas de planificación existentes tienen, en cierta medida, serias limitaciones para diseñar en la práctica una topología fiable de WSN: Sólo unos pocos abordan la cuestión del despliegue 3D mientras que existe una gran cantidad de trabajos que colocan los dispositivos en 2D. Si no se analiza la dimensión completa (3D), los efectos del entorno en el desempeño de WSN no se estudian por completo, por lo que los valores de los parámetros evaluados, como la conectividad y la cobertura de detección, no son lo suficientemente precisos para tomar la decisión correcta. Aún en menor medida los métodos de planificación modelan la cobertura de los sensores y la propagación de la señal de radio teniendo en cuenta un escenario realista donde existan obstáculos. Las señales de radio en el mundo real siguen una propagación multicamino, en la que los caminos directos, los caminos reflejados y los caminos difractados contribuyen a la intensidad de la señal recibida. Además, los obstáculos entre el recorrido del sensor y los objetos pueden bloquear las señales de detección y por lo tanto crear áreas sin cobertura en la aplicación. Ninguno de los algoritmos de planificación existentes modelan el tiempo de vida de la red y la capacidad de entrega de paquetes correctamente y prácticamente. A menudo se emplean formulaciones unilaterales y poco realistas. Los objetivos de optimización son a menudo tratados unilateralmente en los trabajos actuales. Sin una evaluación exhaustiva de los parámetros importantes, el rendimiento previsto de las redes inalámbricas de sensores no puede ser fiable y totalmente optimizado. Por lo general, el modelado del entorno conlleva mucho tiempo y tiene un coste muy alto, pero ninguno de los trabajos actuales propone algún método para modelar el entorno de despliegue 3D con eficiencia y precisión. Por lo tanto, muchos investigadores están limitados por este problema y sus algoritmos sólo se pueden evaluar en el mismo escenario, sin la posibilidad de probar la solidez y viabilidad para las implementaciones en diferentes entornos. En esta tesis, se propone una nueva metodología de planificación así como una herramienta inteligente de planificación de redes de sensores inalámbricas para ayudar a los diseñadores a planificar WSNs fiables de una manera eficiente. En primer lugar, se propone un nuevo método para modelar demanera eficiente y automática los ambientes interiores y exteriores en 3D. Según nuestros conocimientos hasta la fecha, esta es la primera vez que las ventajas del algoritmo de _image understanding_se aplican para reconstruir automáticamente los escenarios exteriores e interiores en 3D para analizar la propagación de la señal y viii la planificación de la red. Los resultados experimentales indican que la metodología propuesta es capaz de reconocer con precisión los diferentes objetos presentes en las imágenes satelitales de las regiones objetivo en el exterior y de la planta escaneada en el interior. Su mecanismo ofrece a los usuarios la flexibilidad para reconstruir los diferentes tipos de entornos sin ninguna interacción humana. De este modo se reduce considerablemente el esfuerzo humano, el coste y el tiempo invertido en la reconstrucción de una base de datos geográfica con información 3D, permitiendo así que los diseñadores se concentren en los temas de planificación. En segundo lugar, se ha desarrollado un motor de trazado de rayos (en inglés ray tracing) eficiente para modelar con precisión la propagación de la señal de radio y la señal de los sensores en el mapa 3D construido. El motor contribuye a la eficiencia y la precisión de los resultados estimados. Mediante el uso de los conceptos de procesamiento de imágenes, incluyendo el algoritmo del árbol kd para la división del espacio y el algoritmo _polar sweep_modificado, los rayos se trazan de manera eficiente sin la detección de todas las primitivas en la escena. El modelo de propagación de radio que se propone no sólo considera los materiales de los obstáculos, sino también su ubicación a lo largo de la ruta de señal. La señal de los sensores de los nodos, que es sensible a los obstáculos, se ve beneficiada por la detección de objetos llevada a cabo por el algoritmo de trazado de rayos. El rendimiento de este método de modelado es robusto y preciso en comparación con los métodos convencionales, y los resultados experimentales indican que esta metodología es adecuada tanto para escenas urbanas al aire libre como para ambientes interiores. Por otra parte, se puede aplicar a cualquier comunicación GSM o protocolo ZigBee mediante la variación de la frecuencia del modelo de propagación de radio. En tercer lugar, se propone un método de planificación de WSNs para hacer frente a los desafíos mencionados anteriormente y desplegar redes de sensores fiables de manera eficiente. Se modelan más parámetros (conectividad, cobertura, coste, tiempo de vida, la latencia de paquetes y tasa de caída de paquetes) en comparación con otros trabajos. Especialmente el método de trazado de rayos 3D se utiliza para modelar el enlace de radio y señal de los sensores que son sensibles a la obstrucción de obstáculos; el enrutamiento de la red se construye utilizando el protocolo AODV; la longevidad de la red, retardo de paquetes ix y tasa de abandono de paquetes se obtienen a través de la simulación de eventos prácticos en el simulador WSNet, y según nuestros conocimientos hasta la fecha, es la primera vez que simulador de red está implicado en un algoritmo de planificación. Por otra parte, se ha desarrollado un algoritmo de optimización multi-objetivo para satisfacer las características de las redes inalámbricas de sensores. La capacidad de proporcionar múltiples soluciones optimizadas de forma simultánea permite a los usuarios tomar sus propias decisiones en consecuencia, obteniendo mejores resultados en comparación con otros algoritmos del estado del arte. iMOST se desarrolla mediante la integración de los algoritmos presentados, para ayudar de forma eficiente a los diseñadores en la planificación de WSNs fiables para diferentes configuraciones. El nombre abreviado iMOST (Intelligent Multi-objective Optimization Sensor network planning Tool) representa una herramienta inteligente de planificación de redes de sensores con optimización multi-objetivo. iMOST contribuye en: (1) Operación conveniente con una interfaz de fácil uso, (2) Reconstrucción eficiente y automática de una base de datos con información 3D y diseño rápido de objetos 3D para ambientes interiores y exteriores, (3) Proporciona varias soluciones de despliegue optimizadas para los multi-objetivo en 3D y permite a los usuarios configurar las propiedades de red, por lo que puede adaptarse a diversas aplicaciones de WSN, (4) las soluciones de implementación en el espacio 3D y el correspondiente rendimiento evaluado se presentan visualmente a los usuarios, y (5) El _Node Placement Module_de iMOST está disponible en línea, así como el código fuente de las otras dos heurísticas de planificación. Por lo tanto los diseñadores WSN se beneficiarán de esta herramienta para la construcción eficiente de la base de datos con información del entorno, la planificación práctica y eficiente de WSNs fiables tanto para aplicaciones interiores y exteriores. Con los códigos fuente abiertos, son capaces de comparar sus algoritmos desarrollados con los nuestros para contribuir a este campo académico. Por último, se obtienen resultados reales sólidos tanto para la planificación de WSN en interiores y exteriores. Los despliegues se han realizado tanto para ambientes de interior y como para ambientes de exterior utilizando las soluciones de planificación propuestas. Los resultados medidos coinciden en gran medida con los resultados estimados. El algoritmo de planificación x propuesto se adapta convenientemente al deiseño de redes de sensores inalámbricas, y ofrece flexibilidad para planificar los despliegues 3D a pequeña y gran escala tanto en interiores como en exteriores. La tesis se estructura en 7 capítulos. En el Capítulo 1, se presentan las aplicaciones de WSN y motivaciones de este trabajo, se revisan los algoritmos y herramientas de planificación del estado del arte, se presentan los retos y se describe brevemente la metodología propuesta. En el Capítulo 2, se presenta la metodología de reconstrucción de entornos 3D propuesta y su rendimiento es evaluado tanto para espacios exteriores como para espacios interiores. El motor de trazado de rayos desarrollado y el método de modelado de propagación de radio propuesto se describen en detalle en el Capítulo 3, evaluándose en términos de eficiencia computacional y precisión. En el Capítulo 4 se presenta el modelado de los parámetros importantes de las WSNs y el algoritmo de planificación de optimización multi-objetivo propuesto, el rendimiento se compara con los otros algoritmos de planificación descritos en el estado del arte. La herramienta inteligente de planificación de redes de sensores inalámbricas, iMOST, se describe en el Capítulo 5. En el Capítulo 6 se llevan a cabo despliegues reales de acuerdo a las soluciones previstas para los escenarios interiores y exteriores, se miden los datos importantes y se analizan los resultados. En el Capítulo 7 se concluye la tesis y se discute acerca de los trabajos futuros.

Massively parallelizable list-mode reconstruction using a Monte Carlo-based elliptical Gaussian model

Purpose: A fully three-dimensional (3D) massively parallelizable list-mode ordered-subsets expectation-maximization (LM-OSEM) reconstruction algorithm has been developed for high-resolution PET cameras. System response probabilities are calculated online from a set of parameters derived from Monte Carlo simulations. The shape of a system response for a given line of response (LOR) has been shown to be asymmetrical around the LOR. This work has been focused on the development of efficient region-search techniques to sample the system response probabilities, which are suitable for asymmetric kernel models, including elliptical Gaussian models that allow for high accuracy and high parallelization efficiency. The novel region-search scheme using variable kernel models is applied in the proposed PET reconstruction algorithm. Methods: A novel region-search technique has been used to sample the probability density function in correspondence with a small dynamic subset of the field of view that constitutes the region of response (ROR). The ROR is identified around the LOR by searching for any voxel within a dynamically calculated contour. The contour condition is currently defined as a fixed threshold over the posterior probability, and arbitrary kernel models can be applied using a numerical approach. The processing of the LORs is distributed in batches among the available computing devices, then, individual LORs are processed within different processing units. In this way, both multicore and multiple many-core processing units can be efficiently exploited. Tests have been conducted with probability models that take into account the noncolinearity, positron range, and crystal penetration effects, that produced tubes of response with varying elliptical sections whose axes were a function of the crystal's thickness and angle of incidence of the given LOR. The algorithm treats the probability model as a 3D scalar field defined within a reference system aligned with the ideal LOR. Results: This new technique provides superior image quality in terms of signal-to-noise ratio as compared with the histogram-mode method based on precomputed system matrices available for a commercial small animal scanner. Reconstruction times can be kept low with the use of multicore, many-core architectures, including multiple graphic processing units. Conclusions: A highly parallelizable LM reconstruction method has been proposed based on Monte Carlo simulations and new parallelization techniques aimed at improving the reconstruction speed and the image signal-to-noise of a given OSEM algorithm. The method has been validated using simulated and real phantoms. A special advantage of the new method is the possibility of defining dynamically the cut-off threshold over the calculated probabilities thus allowing for a direct control on the trade-off between speed and quality during the reconstruction.

Integrable high order UWB pulse photonic generator based on cross phase modulation in a SOA-MZI

We propose and experimentally demonstrate a potentially integrable optical scheme to generate high order UWB pulses. The technique is based on exploiting the cross phase modulation generated in an InGaAsP Mach-Zehnder interferometer containing integrated semiconductor optical amplifiers, and is also adaptable to different pulse modulation formats through an optical processing unit which allows to control of the amplitude, polarity and time delay of the generated taps.

Multi-resolution model-based traffic sign detection and tracking

In this paper we propose an innovative approach to tackle the problem of traffic sign detection using a computer vision algorithm and taking into account real-time operation constraints, trying to establish intelligent strategies to simplify as much as possible the algorithm complexity and to speed up the process. Firstly, a set of candidates is generated according to a color segmentation stage, followed by a region analysis strategy, where spatial characteristic of previously detected objects are taken into account. Finally, temporal coherence is introduced by means of a tracking scheme, performed using a Kalman filter for each potential candidate. Taking into consideration time constraints, efficiency is achieved two-fold: on the one side, a multi-resolution strategy is adopted for segmentation, where global operation will be applied only to low-resolution images, increasing the resolution to the maximum only when a potential road sign is being tracked. On the other side, we take advantage of the expected spacing between traffic signs. Namely, the tracking of objects of interest allows to generate inhibition areas, which are those ones where no new traffic signs are expected to appear due to the existence of a TS in the neighborhood. The proposed solution has been tested with real sequences in both urban areas and highways, and proved to achieve higher computational efficiency, especially as a result of the multi-resolution approach.