A new strategy for the synthesis of 3-cinnamoyl-2-styrylchromones and their transformation into new xanthenodiones derivatives

23rd ISHC Congress will be held in Glasgow, Scotland from July 31 August 4, 2011.

Synthesis of new 1,8-dihydroxy-9h-xanthen-9-ones

XXVth European Colloquium on Heterocyclic Chemistry, Reading, UK, 13 – 17 Agosto de 2012.

New xanthenodione: synthesis and antioxidant activity evaluation

6th Spanish-Portuguese-Japanese Organic Chemistry Symposium, Lisboa, de 18 a 20 de Julho de 2012 (Poster Communication).

Building the «true evolutionism»: Darwin's impact on Henri Bergson's thought

The paper focuses on the importance of Darwin’s work for the shaping of Henri Bergson’s philosophy, bearing on mind that the two authors first intercepted symbolically in 1859, when On the Origin of Species was published and Bergson was born. Bergson studied the biological sciences of his time, whose results were integrated in a metaphysical thought. He belonged to spiritualistic positivism, a philosophy that goes from the positive data of sciences and finds the ultimate explanation of reality in a spiritual principle. He was interested in the positive evolution of the natural world and in the works of naturalists such as Lamarck, De Vries or Eimer. Darwin was among these authors, being responsible for a vision of evolution that went from the scientific level to other domains. Bergson defends the “insufficiency of pure Darwinism” by pointing out the necessity to compensate scientific evolution with an internal metaphysical reading of the real, which he considered to be “true evolutionism”. This criticism is the most visible aspect of the relations between both works. However, an attentive look verifies that Darwin’s influence overcomes the divergence of positions concerning the extent of “evolution”. The French philosopher knew not only the 1859’s bestseller, but also studies by Darwin about ethology, entomology and botany, which contributed to the fact that the naturalist’s impact gained fundamental importance in Bergson’s philosophical perspective.

Uma cidade portuária: a Horta entre 1880 e 1926. Sociedade e cultura com a política em fundo

Tese de Doutoramento, História (História Contemporânea), 29 de Novembro de 2013, Universidade dos Açores.

Intervenção pedagógica do futuro educador/professor e avaliação interativa nas práticas de estagiários e no discurso de docentes

Mestrado (PES II), Educação Pré-Escolar e Ensino do 1º Ciclo do Ensino Básico, 3 de Julho de 2014, Universidade dos Açores.

Xanthenedione derivatives, new promising antioxidant and acetylcholinesterase inhibitor agents

Natural and synthetic xanthone derivatives are well-known for their ability to act as antioxidants and/or enzyme inhibitors. This paper aims to present a successful synthetic methodology towards xanthenedione derivatives and the study of their aromatization to xanthones. Additionally their ability to reduce Fe(III), to scavenge DPPH radicals and to inhibit AChE was evaluated. The results demonstrated that xanthenedione derivative 5e, bearing a catechol unit, showed higher reduction capacity than BHT and similar to quercetin, strong DPPH scavenging activity (EC50 = 3.79 ± 0.06 μM) and it was also showed to be a potent AChEI (IC50 = 31.0 ± 0.09 μM) when compared to galantamine (IC50 = 211.8 ± 9.5 μM).

Contribuição para o desenvolvimento e a implementação do sistema de planeamento de emergência na Região Autónoma dos Açores

Dissertação de Mestrado em Vulcanologia e Riscos Geológicos

Necessidades dos idosos do concelho da Praia da Vitória em cuidados continuados domiciliários

Dissertação de Mestrado em Gerontologia Social