1 resultado para Practical training in school
em Instituto Nacional de Saúde de Portugal
Filtro por publicador
- JISC Information Environment Repository (1)
- ABACUS. Repositorio de Producción Científica - Universidad Europea (1)
- Aberdeen University (2)
- Abertay Research Collections - Abertay University’s repository (2)
- Aberystwyth University Repository - Reino Unido (1)
- Academic Archive On-line (Jönköping University; Sweden) (1)
- Academic Archive On-line (Karlstad University; Sweden) (1)
- Academic Archive On-line (Mid Sweden University; Sweden) (1)
- Academic Archive On-line (Stockholm University; Sweden) (1)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- Adam Mickiewicz University Repository (1)
- Aquatic Commons (6)
- Archive of European Integration (63)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (2)
- Aston University Research Archive (11)
- B-Digital - Universidade Fernando Pessoa - Portugal (1)
- Biblioteca de Teses e Dissertações da USP (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (17)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (3)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (3)
- Bioline International (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (64)
- Boston University Digital Common (2)
- Brock University, Canada (10)
- Bucknell University Digital Commons - Pensilvania - USA (2)
- Bulgarian Digital Mathematics Library at IMI-BAS (3)
- Cambridge University Engineering Department Publications Database (7)
- CentAUR: Central Archive University of Reading - UK (18)
- Center for Jewish History Digital Collections (1)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (1)
- Clark Digital Commons--knowledge; creativity; research; and innovation of Clark University (1)
- Cochin University of Science & Technology (CUSAT), India (5)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (16)
- CORA - Cork Open Research Archive - University College Cork - Ireland (3)
- Cornell: DigitalCommons@ILR (1)
- Dalarna University College Electronic Archive (4)
- Deakin Research Online - Australia (127)
- Digital Commons @ DU | University of Denver Research (2)
- Digital Commons at Florida International University (9)
- Digital Peer Publishing (1)
- DigitalCommons@The Texas Medical Center (3)
- DRUM (Digital Repository at the University of Maryland) (1)
- Duke University (5)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (1)
- Escola Superior de Educação de Paula Frassinetti (1)
- Fachlicher Dokumentenserver Paedagogik/Erziehungswissenschaften (7)
- Funes: Repositorio digital de documentos en Educación Matemática - Colombia (1)
- Greenwich Academic Literature Archive - UK (3)
- Harvard University (1)
- Helda - Digital Repository of University of Helsinki (7)
- Indian Institute of Science - Bangalore - Índia (6)
- Institute of Public Health in Ireland, Ireland (1)
- Instituto Nacional de Saúde de Portugal (1)
- Instituto Politécnico de Leiria (1)
- Instituto Politécnico de Viseu (1)
- Instituto Politécnico do Porto, Portugal (2)
- Martin Luther Universitat Halle Wittenberg, Germany (1)
- Memoria Académica - FaHCE, UNLP - Argentina (6)
- Memorial University Research Repository (1)
- Ministerio de Cultura, Spain (10)
- National Center for Biotechnology Information - NCBI (3)
- Nottingham eTheses (1)
- Open University Netherlands (2)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (1)
- Portal de Revistas Científicas Complutenses - Espanha (7)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (43)
- Queensland University of Technology - ePrints Archive (181)
- ReCiL - Repositório Científico Lusófona - Grupo Lusófona, Portugal (2)
- Repositorio Académico de la Universidad Nacional de Costa Rica (1)
- Repositório Científico da Escola Superior de Enfermagem de Coimbra (1)
- Repositório Científico da Universidade de Évora - Portugal (4)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (1)
- Repositório Digital da UNIVERSIDADE DA MADEIRA - Portugal (1)
- Repositório Digital da Universidade Municipal de São Caetano do Sul - USCS (1)
- Repositório Institucional da Universidade de Aveiro - Portugal (1)
- Repositório Institucional da Universidade Federal do Rio Grande do Norte (1)
- Repositorio Institucional de la Universidad de Almería (1)
- Repositorio Institucional de la Universidad de Málaga (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (40)
- Research Open Access Repository of the University of East London. (1)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (1)
- School of Medicine, Washington University, United States (5)
- Scielo España (1)
- Universidad Autónoma de Nuevo León, Mexico (2)
- Universidad de Alicante (5)
- Universidad del Rosario, Colombia (2)
- Universidad Politécnica de Madrid (7)
- Universidade de Lisboa - Repositório Aberto (6)
- Universidade Federal do Rio Grande do Norte (UFRN) (4)
- Université de Lausanne, Switzerland (1)
- Université de Montréal (1)
- Université de Montréal, Canada (3)
- University of Canberra Research Repository - Australia (1)
- University of Michigan (105)
- University of Queensland eSpace - Australia (40)
- University of Southampton, United Kingdom (1)
- University of Washington (2)
- WestminsterResearch - UK (1)
- Worcester Research and Publications - Worcester Research and Publications - UK (2)
Resumo:
The main purpose of this pilot study was to investigate the possible influence of genetic polymorphisms of the hOGG1 (Ser326Cys) gene in DNA damage and repair activity by 8-oxoguanine DNA glycosylase 1 (OGG1 enzyme) in response to 16 weeks of combined physical exercise training. Thirty-two healthy Caucasian men (40-74 years old) were enrolled in this study. All the subjects were submitted to a training of 16 weeks of combined physical exercise. The subjects with Ser/Ser genotype were considered as wild-type group (WTG), and Ser/Cys and Cys/Cys genotype were analysed together as mutant group (MG). We used comet assay in conjunction with formamidopyrimidine DNA glycoslyase (FPG) to analyse both strand breaks and FPG-sensitive sites. DNA repair activity were also analysed with the comet assay technique. Our results showed no differences between DNA damage (both strand breaks and FPG-sensitive sites) and repair activity (OGG1) between genotype groups (in the pre-training condition). Regarding the possible influence of genotype in the response to 16 weeks of physical exercise training, the results revealed a decrease in DNA strand breaks in both groups, a decrease in FPG-sensitive sites and an increase in total antioxidant capacity in the WTG, but no changes were found in MG. No significant changes in DNA repair activity was observed in both genotype groups with physical exercise training. This preliminary study suggests the possibility of different responses in DNA damage to the physical exercise training, considering the hOGG1 Ser326Cys polymorphism.