1 resultado para Magnitude of the soul
em Instituto Gulbenkian de Ciência
Filtro por publicador
- Academic Research Repository at Institute of Developing Economies (3)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (13)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (3)
- Aquatic Commons (1)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (5)
- Archimer: Archive de l'Institut francais de recherche pour l'exploitation de la mer (1)
- Archive of European Integration (1)
- Aston University Research Archive (20)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (16)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (39)
- Biblioteca Virtual del Sistema Sanitario Público de Andalucía (BV-SSPA), Junta de Andalucía. Consejería de Salud y Bienestar Social, Spain (1)
- Bioline International (1)
- Blue Tiger Commons - Lincoln University - USA (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (39)
- Brock University, Canada (8)
- Bucknell University Digital Commons - Pensilvania - USA (2)
- CaltechTHESIS (1)
- CentAUR: Central Archive University of Reading - UK (112)
- Central European University - Research Support Scheme (1)
- CiencIPCA - Instituto Politécnico do Cávado e do Ave, Portugal (2)
- Cochin University of Science & Technology (CUSAT), India (6)
- Collection Of Biostatistics Research Archive (2)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (11)
- Consorci de Serveis Universitaris de Catalunya (CSUC), Spain (15)
- CORA - Cork Open Research Archive - University College Cork - Ireland (3)
- Dalarna University College Electronic Archive (5)
- Digital Archives@Colby (1)
- Digital Commons - Michigan Tech (5)
- Digital Commons @ DU | University of Denver Research (1)
- Digital Commons at Florida International University (7)
- DigitalCommons - The University of Maine Research (5)
- DigitalCommons@The Texas Medical Center (9)
- Digitale Sammlungen - Goethe-Universität Frankfurt am Main (1)
- Diposit Digital de la UB - Universidade de Barcelona (1)
- Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland (2)
- DRUM (Digital Repository at the University of Maryland) (1)
- Duke University (3)
- Glasgow Theses Service (2)
- Harvard University (5)
- Helvia: Repositorio Institucional de la Universidad de Córdoba (2)
- Illinois Digital Environment for Access to Learning and Scholarship Repository (4)
- Institute of Public Health in Ireland, Ireland (1)
- Instituto Gulbenkian de Ciência (1)
- Instituto Nacional de Saúde de Portugal (1)
- Instituto Politécnico do Porto, Portugal (2)
- Iowa Publications Online (IPO) - State Library, State of Iowa (Iowa), United States (3)
- Massachusetts Institute of Technology (1)
- National Center for Biotechnology Information - NCBI (25)
- Portal de Revistas Científicas Complutenses - Espanha (4)
- Publishing Network for Geoscientific & Environmental Data (70)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (2)
- Repositorio Académico de la Universidad Nacional de Costa Rica (1)
- Repositório Científico da Universidade de Évora - Portugal (2)
- Repositório Científico do Instituto Politécnico de Lisboa - Portugal (4)
- Repositório da Produção Científica e Intelectual da Unicamp (113)
- Repositório digital da Fundação Getúlio Vargas - FGV (3)
- REPOSITORIO DIGITAL IMARPE - INSTITUTO DEL MAR DEL PERÚ, Peru (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (47)
- Research Open Access Repository of the University of East London. (1)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (4)
- SAPIENTIA - Universidade do Algarve - Portugal (1)
- Savoirs UdeS : plateforme de diffusion de la production intellectuelle de l’Université de Sherbrooke - Canada (1)
- Scielo España (1)
- Scielo Saúde Pública - SP (34)
- Scottish Institute for Research in Economics (SIRE) (SIRE), United Kingdom (3)
- South Carolina State Documents Depository (1)
- Universidad de Alicante (8)
- Universidad del Rosario, Colombia (2)
- Universidad Politécnica de Madrid (21)
- Universidade Complutense de Madrid (3)
- Universidade do Algarve (1)
- Universidade do Minho (3)
- Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP) (1)
- Universidade Federal do Pará (1)
- Universidade Federal do Rio Grande do Norte (UFRN) (1)
- Universidade Técnica de Lisboa (1)
- Universitat de Girona, Spain (1)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (4)
- Université de Lausanne, Switzerland (51)
- Université de Montréal (1)
- Université de Montréal, Canada (9)
- University of Connecticut - USA (2)
- University of Michigan (88)
- University of Queensland eSpace - Australia (55)
- University of Washington (2)
- WestminsterResearch - UK (1)
Resumo:
Pyrimethanil is a fungicide mostly applied in vineyards. When misused, residue levels detected in grape must or in the environment may be of concern. The present work aimed to analyze mechanisms underlying response to deleterious effects of pyrimethanil in the eukaryotic model Saccharomyces cerevisiae. Pyrimethanil concentration-dependent effects at phenotypic (inhibition of growth) and transcriptomic levels were examined. For transcriptional profiling, analysis focused on two sublethal exposure conditions that inhibited yeast growth by 20% or 50% compared with control cells not exposed to the fungicide. Gene expression modifications increased with the magnitude of growth inhibition, in numbers and fold-change of differentially expressed genes and in diversity of over-represented functional categories. These included mostly biosynthesis of arginine and sulfur amino acids metabolism, as well as energy conservation, antioxidant response, and multidrug transport. Several pyrimethanil-responsive genes encoded proteins sharing significant homology with proteins from phytopathogenic fungi and ecologically relevant higher eukaryotes.