Relación entre atrofia cortical difusa y desempeño cognitivo : estudio en población mayor de 60 años en un hospital universitario en la ciudad de Bogotá


Autoria(s): Cogollos, Jenny Natalia; Piedrahita, Paula Viviana; Urquijo, Paula Andrea
Contribuinte(s)

López, Jhon Álvaro

Data(s)

13/12/2016

Resumo

El presente trabajo tuvo como objetivo evaluar la existencia de la relación entre la atrofia cortical difusa objetivada por neuroimagenes cerebrales y desempeños cognitivos determinados mediante la aplicación de pruebas neuropsicológicas que evalúan memoria de trabajo, razonamiento simbólico verbal y memoria anterógrada declarativa. Participaron 114 sujetos reclutados en el Hospital Universitario Mayor Méderi de la ciudad de Bogotá mediante muestreo de conveniencia. Los resultados arrojaron diferencias significativas entre los dos grupos (pacientes con diagnóstico de atrofia cortical difusa y pacientes con neuroimagenes interpretadas como dentro de los límites normales) en todas las pruebas neuropsicológicas aplicadas. Respecto a las variables demográficas se pudo observar que el grado de escolaridad contribuye como factor neuroprotector de un posible deterioro cognitivo. Tales hallazgos son importantes para determinar protocoles tempranos de detección de posible instalación de enfermedades neurodegenerativas primarias.

The objective of this study was to evaluate if there is a relationship between diffuse cortical atrophy objectified by cerebral neuroimages and cognitive performances determined by the application of neuropsychological tests that evaluate working memory, verbal symbolic reasoning and declarative anterograde memory. 114 participants were recruited at the Hospital Universitario Mayor Méderi of Bogotá through a convenience sample. The results showed significant differences between the two groups (patients with diagnosis of diffuse cortical atrophy and patients with neuroimages interpreted as within normal limits) in al applied neuropsychological tests. Regarding the demographic variables, it was observed that the level of schooling contributes as a neuroprotective factor of a possible cognitive impairment. Such findings are important in determining early protocols for the detection of possible primary neurodegenerative diseases.

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http://repository.urosario.edu.co/handle/10336/12751

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spa

Publicador

Escuela de Medicina y Ciencias de la Salud

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info:eu-repo/semantics/openAccess

Fonte

instname:Universidad del Rosario

reponame:Repositorio Institucional EdocUR

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TPS

Palavras-Chave #616 #Atrofia #Psicología #Desarrollo cognitivo #Diffuse cortical atrophy #Cognitive performance #Working memory #Verbal symbolic reasoning #Declarative anterograde memory #Neuroimage
Tipo

info:eu-repo/semantics/bachelorThesis

info:eu-repo/semantics/acceptedVersion