Caracterización clínica de pacientes pediátricos con tumores cerebrales primarios en un hospital de Bogotá entre 2007-2014
Contribuinte(s) |
Ozaeta, Daniel Galindo Ángel, Andrés Felipe |
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Data(s) |
21/11/2016
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Resumo |
Introducción: En la población pediátrica los tumores cerebrales son la segunda causa de cáncer, la dificultad en su identificación produce tardanza en su diagnóstico y pocos estudios de caracterización han sido realizados en Colombia. Se realizó un estudio para identificar las características en el curso de la enfermedad. Materiales y Métodos: Estudio observacional, descriptivo, de corte transversal con pacientes pediátricos con tumores cerebrales primarios en la clínica infantil Colsubsidio entre 2007-2014. Se revisaron sistemáticamente las historias clínicas de niños con este diagnóstico en patología y posteriormente se desarrolló un análisis univariado de estos. Resultados: 56 niños fueron incluidos, encontrando que el número de consultas previas al diagnóstico fueron más de 4 con un promedio de tiempo entre la evolución de los síntomas y el diagnóstico de 161,1 días. Para la clasificación de la OMS los más frecuentes fueron los embrionarios y astrocíticos, entre estos el meduloblastoma es el más común por histología (14,29%), 50% de los pacientes presentaron remisión y 29,41% fallecieron. Discusión: Los tumores cerebrales primarios son una patología frecuente y con alta morbimortalidad. Este estudio mostró datos epidemiológicos y clínicos similares a la literatura respecto al sexo, edad, tipo de tumor y amplios rangos de tiempo en la evolución de síntomas lo que muestra la naturaleza variable de la enfermedad; se evidencia el diagnóstico tardío en pacientes reconsultantes por el mismo síntoma lo que es frecuente en estos pacientes al igual que en otros estudios nacionales. Backround: In the pediatric population, the brain neoplasms are the second leading cause of cancer in this group, the difficulty in identifying their causes delay the diagnosis and its characterization, just a few studies have been conducted in Colombia. This study aims to identify the characteristics in the course of the disease. Materials and Methods: A observational, descriptive, cross-sectional study in pediatric patients with primary brain tumors in children's clinical Colsubsidio during 2007-2014 was performed. The medical records of children with patology diagnosis of central nervous system neoplasms were systematically reviewed; subsequently was developed a univariate analysis of this. Results: A total of 56 children were included, the number of consultations prior to diagnosis were more than 4, the average time between the onset of symptoms until diagnosis was 161.1 days. Using the WHO classification the most frequent neoplasms were the embryonic and astrocytic tumors, the medulloblastoma is the most frequent tumor by histology with a frequency of 14.29%. 50% of patients had remission and 29.41% died. Discussion: The brain neoplasms are a frequent pathology with high morbidity and mortality. This study showed epidemiological and clinical data similar to the literature about the sex, age, type of tumor and wide ranges of time of symptoms evolution, which shows the variable nature of the disease, it is evident the late diagnosis in patients reconsulting by same sintom that is common in this study and in other national studies. |
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application/pdf |
Identificador | |
Idioma(s) |
spa |
Publicador |
Facultad de medicina |
Direitos |
info:eu-repo/semantics/openAccess |
Fonte |
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Palavras-Chave | #Tumores en niños #618.92994 #Neoplasmas en niños -- Casos clínicos #Neoplacias -- Cerebro -- Estudio de caso #Brain neoplasms #Central nervous system neoplasms #Prognosis #Mortality #Survival |
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info:eu-repo/semantics/bachelorThesis info:eu-repo/semantics/acceptedVersion |