Molecular organization of small plasmids bearing blaTEM-1 and conferring resistance to β-lactams in Haemophilus influenzae
Data(s) |
01/09/2012
|
---|---|
Resumo |
TEM-1 is the dominant β-lactamase of Haemophilus influenzae and can be located on small plasmids. Three distinct plasmids with sizes from 4,304 to 5,646 nucleotides (nt) were characterized: pA1606, pA1209, and pPN223. In addition to TEM-1 and a replication enzyme of the Rep 3 superfamily, pA1606 carries a Tn3 resolvase gene and pA1606 and pA1209 carry an open reading frame (ORF) similar to a plasmid recombination enzyme gene described in Gram-positive bacteria. The plasmids transformed strain Rd to the ampicillin-resistant phenotype. |
Formato |
application/pdf |
Identificador | |
Idioma(s) |
en |
Publicador |
American Society for Microbiology |
Relação |
http://eprints.ucm.es/39668/ http://aac.asm.org/content/56/9/4958.full doi:10.1128/AAC.00408-12 |
Direitos |
info:eu-repo/semantics/restrictedAccess |
Palavras-Chave | #Veterinaria |
Tipo |
info:eu-repo/semantics/article PeerReviewed |