Using steric bulk for selective recognition; blocking the binding site to differentiate guests
Data(s) |
01/01/2016
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Resumo |
Selectivity is demonstrated in a supramolecular host:guest system using a receptor with a non-linear binding site. For the "open" receptor 1 strong binding for both flexible and rigid guests was observed. Receptor 2, with a "blocked" binding site, also bound flexible guests effectively but its affinity for rigid guests was 50 fold lower. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Royal Society of Chemistry |
Relação |
DP140100227 http://dro.deakin.edu.au/eserv/DU:30085154/robson-usingstericbulk-2016.pdf http://www.dx.doi.org/10.1039/c6cc04549a |
Direitos |
2016, Royal Society of Chemistry |
Palavras-Chave | #Science & Technology #Physical Sciences #Chemistry, Multidisciplinary #Chemistry #ANION RECOGNITION #MOLECULAR HOSTS #LIGAND-BINDING #RECEPTORS #9,10-DIHYDROFULVALENE #COMPLEXES #CYCLOADDITION #DERIVATIVES #FRAMEWORKS #DESIGN |
Tipo |
Journal Article |