Delivery of fluorouracil and siRNA by mesoporous silica nanoparticles to drug resistant colorectal cancer


Autoria(s): Chen, Lijue
Contribuinte(s)

Kong, Lingxue

Duan Wei

Shigdar Sarah

She, Fenghua (Mary)

Data(s)

01/11/2015

Resumo

 Mesoporous silica nanoparticle based drug and gene delivery system was developed to overcome the acquired drug resistance in colorectal cancer by targeted delivery of anti-cancer drug in the cytoplasm of the cancer cells and silencing the gene expression related to drug resistance.

Identificador

http://hdl.handle.net/10536/DRO/DU:30085489

Idioma(s)

eng

Publicador

Deakin University, Institute for Frontier Materials

Relação

http://dro.deakin.edu.au/eserv/DU:30085489/chen-agreement-2016.pdf

http://dro.deakin.edu.au/eserv/DU:30085489/chen-deliveryof-2016A.pdf

Direitos

The author

Palavras-Chave #colorectal cancer #gene delivery system #drug resistance #nanobiotechnology
Tipo

Thesis