Serum testosterone levels relate to both frailty and ADL in octogenarian males : Lilacs study, New Zealand

Serum testosterone (T) levels in men decline with age. Low T levels are associated with sarcopenia and frailty in ‘younger old’ men (generally <80 years). T levels have not previously been associated with disability in older men, despite associations between T and physical function and quality of life. There is no consensus on whether older men with low T levels should receive testosterone supplementation to prevent/‘treat’ frailty. We explored associations between T levels and both frailty and disability in a cohort of octogenarian males.