Cancer stem cell targeted therapy: progress amid controversies
Data(s) |
19/10/2015
|
---|---|
Resumo |
Although cancer stem cells have been well characterized in numerous malignancies, the fundamental characteristics of this group of cells, however, have been challenged by some recent observations: cancer stem cells may not necessary to be rare within tumors; cancer stem cells and non-cancer stem cells may undergo reversible phenotypic changes; and the cancer stem cells phenotype can vary substantially between patients. Here the current status and progresses of cancer stem cells theory is illustrated and via providing a panoramic view of cancer therapy, we addressed the recent controversies regarding the feasibility of cancer stem cells targeted anti-cancer therapy. |
Identificador | |
Idioma(s) |
eng |
Publicador |
Impact Journals |
Relação |
http://dro.deakin.edu.au/eserv/DU:30080436/wang-cancerstem-2015.pdf http://www.dx.doi.org/10.18632/oncotarget.6176 |
Direitos |
2015, The Authors |
Palavras-Chave | #anti-cancer treatment #cancer #cancer stem cell #cancer stem cell marker #cancer stem cell model |
Tipo |
Journal Article |