6-(4-Aminophenyl)-4,5-dihydro-3(2H)-pyridazinone - An important chemical moiety for development of cardioactive agents: A review


Autoria(s): Imran, Mohd; Abida
Cobertura

Origin of publication: Nigeria

Data(s)

27/09/2016

Resumo

6-(4-Aminophenyl)-4,5-dihydro-3(2H)-pyridazinone moiety is a vital structural part of many cardio-active pyridazinone derivatives which are either in clinical use or have been tested in clinical trials. These include imazodan, CI-930, pimobendan, indolidan, levosimendan, SK&F-93741, Y-590, meribendan, NSP-804, NSP-805, bemoradan, senazodan, amipizone, prinoxodan, SKF 95654, siguazodan and KF 15232. This article briefly reviews relevant literature on various reports on the synthesis and use of this moiety for development of cardio-active agents

Formato

html

Identificador

http://www.bioline.org.br/abstract?id=pr16208

Idioma(s)

en

Publicador

Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria

Relação

http://www.tjpr.org; http://www.bioline.org.br/pr

Direitos

Copyright 2016 - Tropical Journal of Pharmaceutical Research

Fonte

Tropical Journal of Pharmaceutical Research (ISSN: 1596-5996) Vol 15 Num 7

Palavras-Chave #6-(4-Aminophenyl)-4,5-dihydro-3(2H)-pyridazinone; Cardio-active agents; Imazodan; Pimobendan; Indolidan; Levosimendan
Tipo

RA