Levels of insulin and HOMA-IR in adolescents in Saltillo, Coahuila, Mexico
Data(s) |
2015
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Resumo |
An alarming rise of obesity in adolescents has been observed, placing them at risk of developing resistance to insulin (IR) and its adverse metabolic consequences such as diabetes mellitus type 2 (DM2), metabolic syndrome and cardiovascular disease. Objective: To know the prevalence of obesity, and the levels of glucose, insulin and HOMA-IR and its association with the BMIz, waist circumference and the pubertal stage in a random sample of adolescents. Materials and methods: 292 adolescents between 12 and 15 years (152 female and 140 male), whose anthropometric measurements (weight, height and waist circumference) were taken, body mass index calculated and Z-score determined. Blood glucose and insulin levels were evaluated from a sample of blood and their HOMA-IR was determined. Results: The results showed that 32.5% were obese, 22.3% were overweight and 23.6% showed adolescent central obesity. Glucose levels (p = 0.016), insulin (p = 0.0001) and HOMA-IR (p = 0.0001) showed significant differences in the group with obesity. Values of the three parameters were increased with the stage of puberty. We found significant differences in the levels of glucose (p = 0.0388), insulin (p = 0.0005) and HOMA-IR (p = 0.0001) between the prepubertal and postpubertal stages. |
Formato |
text |
Identificador |
http://eprints.uanl.mx/11627/1/S1665579615000344_S300_en.pdf González Zavala, M. A. y Velasco Morales, A. y Terrazas Flores, J. J. y De la Cruz Galicia, M. G. y Cepeda Nieto, A. C. y Hernández del Río, A. (2015) Levels of insulin and HOMA-IR in adolescents in Saltillo, Coahuila, Mexico. Medicina universitaria, 17 (67). pp. 80-87. ISSN 1665-5796 |
Idioma(s) |
en |
Publicador |
UANL. Facultad de Medicina |
Relação |
http://eprints.uanl.mx/11627/ |
Direitos |
cc_by_nc_nd |
Palavras-Chave | #RC Medicina Interna, Psiquiatría, Neurología |
Tipo |
Artículo PeerReviewed |