Searching relevant polymorphisms of CYP2B6 in HIV infected patients
| Data(s) |
20/09/2016
20/09/2016
27/11/2015
|
|---|---|
| Resumo |
Poster presented at the From Basic Sciences to Clinical Research - First International Congress of CiiEM. Egas Moniz, Caparica, Portugal, 27- 28 November 2015 "The CYP2B6 belongs to the family of Cytochrome P450 enzymes that catalyze the metabolism of a wide variety of drugs, including the anti-retroviral EFV. The CYP2B6 gene, that has been mapped in the chromosome 19, is highly polymorphic and some SNP, namely 516G>T and 785A>G, are associated with decreased protein expression. These variants are related to phenotypes that are characterized as EFV poor metabolizers, and consequently to episodes of neurotoxicity." |
| Identificador | |
| Idioma(s) |
eng |
| Relação |
info:eu-repo/grantAgreement/FCT/3599-PPCDT/127055/PT |
| Direitos |
openAccess |
| Palavras-Chave | #Polymorphisms #CYP2B6 #HIV |
| Tipo |
conferenceObject |
