68Ga somatostatin analog radiolabelling: The radiopharmacist's point of view
| Contribuinte(s) |
Micro et nanomédecines biomimétiques (MINT) ; Université d'Angers (UA) - Institut National de la Santé et de la Recherche Médicale (INSERM) Centre Hospitalier Universitaire d'Angers (CHU Angers) ; PRES Université Nantes Angers Le Mans [UNAM] |
|---|---|
| Data(s) |
2015
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| Resumo |
International audience <p>68Ga-labelled peptides imaging has emerged during the last decade. This was possible thanks to innovative development in 68Ge/68Ga generator or bifunctional chelates (BFC) able to complex 68Ga and to be linked to various peptides and thus optimize radiolabelling procedures. This present review focuses on radiolabelling of somatostatine (SMS) analogs with 68Ga for clinical applications. In that sense, is discussed the key parameters influencing the radiolabelling, from the elution of 68Ge/68Ga generator to purification of final product, and through the quality control of 68Ga-SMS analog radiopharmaceuticals, as well as the full automation of the radiolabelling process.</p> |
| Identificador |
hal-01392434 https://hal.archives-ouvertes.fr/hal-01392434 DOI : 10.1016/j.mednuc.2015.01.003 OKINA : ua9084 |
| Idioma(s) |
en |
| Publicador |
HAL CCSD |
| Relação |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.mednuc.2015.01.003 |
| Fonte |
ISSN: 09281258 Médecine Nucléaire https://hal.archives-ouvertes.fr/hal-01392434 Médecine Nucléaire, 2015, 39 (1), pp.3-10. <10.1016/j.mednuc.2015.01.003> |
| Palavras-Chave | #[SDV] Life Sciences [q-bio] |
| Tipo |
info:eu-repo/semantics/article Journal articles |
