Influence of P53 on the radiotherapy response of hepatocellular carcinoma


Autoria(s): Gomes, AR; Abrantes, AM; Brito, AF; Laranjo, M; Casalta-Lopes, JE; Gonçalves, AC; Sarmento-Ribeiro, AB; Botelho, MF; Tralhão, JG
Data(s)

11/05/2016

11/05/2016

01/09/2015

Resumo

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it has a poor prognosis and few therapeutic options. Radiotherapy is one of the most effective forms of cancer treatment, and P53 protein is one of the key molecules determining how a cell responds to radiotherapy. The aim of this study was to determine the therapeutic efficacy of iodine-131 in three human HCC cell lines.

Identificador

Clin Mol Hepatol. 2015 Sep;21(3):257-67.

http://hdl.handle.net/10400.4/1898

10.3350/cmh.2015.21.3.257

Idioma(s)

eng

Direitos

openAccess

Palavras-Chave #Carcinoma Hepatocelular #Proteína Supressora de Tumor p53
Tipo

article