The Effect of Dietary Tartrazine on Brain Dopamine and the Behavioral Symptoms of Attention Deficit Hyperactivity Disorder
Contribuinte(s) |
Castonguay, Thomas W. |
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Data(s) |
15/06/2016
15/06/2016
01/05/2016
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Resumo |
Attention Deficit Hyperactivity Disorder is a neurodevelopmental disorder correlated with a decrease in brain dopamine and an increase in behavioral symptoms of hyperactivity and impulsivity. This experiment explored how tartrazine (Yellow #5) impacts these symptoms. After tartrazine administration to Spontaneously Hypertensive Rats (SHR), dopamine concentrations in regions of brain tissue were measured using Enzyme-Linked Immunosorbent Assay analysis. Behavioral testing with a T-maze and open field test measured impulsivity and hyperactivity, respectively. Results indicate that dietary tartrazine increases hyperactive behaviors in the SHR. However, results do not indicate a relationship between dietary tartrazine and brain dopamine. No conclusions regarding the relationship between dietary tartrazine and impulsivity were drawn. |
Identificador |
doi:10.13016/M2VB64 |
Idioma(s) |
en_US |
Relação |
Digital Repository at the University of Maryland Gemstone Program, University of Maryland (College Park, Md) |
Palavras-Chave | #Gemstone Team ATTENT #Attention Deficit Hyperactivity Disorder #tartrazine #brain dopamine |
Tipo |
Thesis |