Assessment of genotoxicity of aflatoxin M1 and B1 contaminated milks after in vitro human digestion


Autoria(s): Ladeira, Carina; Becker-Algeri, Tania Aparecida; Pimenta, Andreia Isabel; Badiale-Furlong, Eliana
Data(s)

04/07/2016

04/07/2016

01/06/2016

Resumo

Introduction - Milk is considered a complete food from the nutritional point of view. Milk can be exposed to various types of contamination, such as mycotoxins. These metabolites are naturally occurring toxic compounds produced by fungi. Several studies on milk samples have reported the presence of aflatoxin B1 (AFB1) and M1 (AFM1), due to the high incidence in samples intended for human consumption, carcinogenicity proven AFB1 and resistance of the contaminants to the process of digestion, making those available for intestinal absorption. Considering these aspects, the objective of this study was to evaluate the genotoxicity of milk samples contaminated by AFB1 and AFM1 before and after the action of lactic acid bacteria using Caco-2 intestinal human cells.

Identificador

Ladeira C, Becker-Algeri TA, Pimenta AI, Badiale-Furlong E. Assessment of genotoxicity of aflatoxin M1 and B1 contaminated milks after in vitro human digestion. In: ICOETOX2016 – International Conference on Occupational & Environmental Toxicology, Porto, 21-23 June 2016.

http://hdl.handle.net/10400.21/6291

Idioma(s)

eng

Relação

http://www.icoetox2016.com/

Direitos

openAccess

http://creativecommons.org/licenses/by-nc/4.0/

Palavras-Chave #Genotoxicity #Aflatoxin M1 #Aflatoxin B1 #Milk #Contaminated food #Mycotoxins #Caco-2 cells
Tipo

conferenceObject