Fc-fusion mimetics
| Data(s) |
29/04/2016
|
|---|---|
| Resumo |
The Fc-fusion mimetic RpR 2 was prepared by disulfide bridging conjugation using a PEG in the place of the Fc. RpR 2 displayed higher affinity for VEGF than aflibercept caused primarily by a slower dissociation rate, which can prolong a drug at its site of action. RpRs have considerable potential for development as stable, organ specific therapeutics. |
| Formato |
text |
| Identificador |
http://roar.uel.ac.uk/5304/1/Fc-fusion%20mimetics.pdf Khalili, Hanieh and Khaw, P. T. and Brocchini, S. (2016) ‘Fc-fusion mimetics’, Biomaterials Science, 4(6), pp. 943-947. |
| Publicador |
Royal Society of Chemistry |
| Relação |
http://dx.doi.org/10.1039/C6BM00077K http://roar.uel.ac.uk/5304/ |
| Tipo |
Article PeerReviewed |
