IL10 Low-Frequency Variants in Behçet's Disease Patients


Autoria(s): Matos, M; Xavier, JM; Abrantes, P; Sousa, I; Rei, N; Davatchi, F; Shahram, F; Jesus, G; Barcelos, F; Vedes, J; Salgado, Manuel; Abdollahi, B; Nadji, A; Moraes-Fontes, MF; Shafiee, N; Ghaderibarmi, F; Vaz Patto, J; Crespo, J; Oliveira, SA
Data(s)

11/08/2016

11/08/2016

08/04/2014

Resumo

To explain the missing heritability after the genome-wide association studies era, sequencing studies allow the identification of low-frequency variants with a stronger effect on disease risk. Common variants in the interleukin 10 gene (IL10) have been consistently associated with Behçet's disease (BD) and the goal of this study is to investigate the role of low-frequency IL10 variants in BD susceptibility.

Identificador

Int J Rheum Dis. 2014 Apr 8.

http://hdl.handle.net/10400.17/2548

10.1111/1756-185X.12369

Idioma(s)

eng

Publicador

Wiley Publishing

Direitos

openAccess

Palavras-Chave #Behçet's disease #IL10 #Low-frequency variants #HCC DAUTOIM
Tipo

article