Ordering Quantiles through Confidence Statements


Autoria(s): de Campos, Cassio P.; Pereira, Carlos A. de B.; Rancoita, Paola M.V.; Polpo, Adriano
Data(s)

08/10/2016

Resumo

Ranking variables according to their relevance to predict an outcome is an important task in biomedicine. For instance, such ranking can be used for selecting a smaller number of genes to then apply other sophisticated experiments only on genes identified as important. A nonparametric method called Quor is designed to provide a confidence value for the order of arbitrary quantiles of different populations using independent samples. This confidence may provide insights about possible differences among groups and yields a ranking of importance for the variables. Computations are efficient and use exact distributions with no need for asymptotic considerations. Experiments with simulated data and with multiple real -omics data sets are performed and they show advantages and disadvantages of the method. Quor has no assumptions but independence of samples, thus it might be a better option when assumptions of other methods cannot be asserted. The software is publicly available on CRAN.

Formato

application/pdf

Identificador

http://pure.qub.ac.uk/portal/en/publications/ordering-quantiles-through-confidence-statements(c13d6cf4-46e0-4eff-9738-6abf9920619d).html

http://dx.doi.org/10.3390/e18100357

http://pure.qub.ac.uk/ws/files/107744955/entropy_18_00357_1_.pdf

Idioma(s)

eng

Direitos

info:eu-repo/semantics/openAccess

Fonte

de Campos , C P , Pereira , C A D B , Rancoita , P M V & Polpo , A 2016 , ' Ordering Quantiles through Confidence Statements ' Entropy , vol 18 , no. 10 , 357 . DOI: 10.3390/e18100357

Tipo

article