The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma


Autoria(s): Mohamed, Abdalla; Sun, Congshan; De Mello, Vanessa; Selfe, Joanna; Missiaglia, Edoardo; Shipley, Janet; Murray, Graeme I; Zammit, Pete S; Wackerhage, Henning
Contribuinte(s)

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Medical Sciences

University of Aberdeen, Medicine, Medical Sciences & Nutrition

University of Aberdeen, University of Aberdeen

University of Aberdeen, East Bio

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Applied Medicine

Data(s)

23/09/2016

23/09/2016

01/09/2016

Resumo

Acknowledgements This study was funded by Sarcoma UK, Friends of Anchor and the Medical Research Council grant number 99477 awarded to HW and PSZ. This work was also supported, in part, by NHS funding to the NIHR Biomedical Research Centre at The Royal Marsden and the Institute of Cancer Research, and the Chris Lucas Trust, UK. We also thank the CCLG Tissue Bank for access to samples, and contributing CCLG centres, including members of the ECMC paediatric network. The CCLG Tissue Bank is funded by Cancer Research UK and CCLG. In addition we would like to thank Prof KunLiang Guan and Prof Malcolm Logan for kindly providing constructs

Peer reviewed

Publisher PDF

Formato

12

Identificador

Mohamed , A , Sun , C , De Mello , V , Selfe , J , Missiaglia , E , Shipley , J , Murray , G I , Zammit , P S & Wackerhage , H 2016 , ' The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma ' The Journal of pathology , vol 240 , no. 1 , pp. 3-14 . , 10.1002/path.4745

0022-3417

PURE: 65963588

PURE UUID: 2d033597-fb85-41a8-9edb-aadd5e132f8e

http://hdl.handle.net/2164/7510

http://dx.doi.org/10.1002/path.4745

Idioma(s)

eng

Relação

The Journal of pathology

Direitos

© 2016 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. https://creativecommons.org/licenses/by/4.0/

Palavras-Chave #hippo pathway #TAZ #WWTR1 #embryonal rhabdomyosarcoma #R Medicine #R
Tipo

Journal article