Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons
Contribuinte(s) |
University of Aberdeen, Natural & Computing Sciences University of Aberdeen, School of Biological Sciences, Biological Sciences University of Aberdeen, Environment and Food Security University of Aberdeen, School of Biological Sciences |
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Data(s) |
25/08/2016
25/08/2016
13/02/2014
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Resumo |
Funding: This work was partially supported by grants from National Basic Research Program of China (2013CB530605; 2014CB942803), from National Natural Science Foundation of China 1230046; 31071252; 81101182) and from Chinese Academy of Sciences (KSCX2-EW-R-05, KJZD-EW-L08). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Peer reviewed Publisher PDF |
Identificador |
Zhang , Z , Hao , C-J , Li , C-G , Zang , D-J , Zhao , J , Li , X-N , Wei , A-H , Wei , Z-B , Yang , L , He , X , Zhen , X-C , Gao , X , Speakman , J R & Li , W 2014 , ' Mutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neurons ' PLoS Genetics , vol 10 , no. 2 , e1004124 . , 10.1371/journal.pgen.1004124 1553-7390 PURE: 70070438 PURE UUID: eba7ec42-70a8-4463-936e-d70c882a2698 PubMed: 24550737 |
Idioma(s) |
eng |
Relação |
PLoS Genetics |
Direitos |
Copyright: © 2014 Zhang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
Palavras-Chave | #Animals #Central Nervous System #Dopamine #Female #Humans #Male #Metabolic Syndrome X #Mice #Monosaccharide Transport Proteins #Mutation #Neurons #Obesity #Receptors, Dopamine D1 #Signal Transduction #Visual Cortex #QH301 Biology #QH301 |
Tipo |
Journal article |