Transporters for Antiretroviral Drugs in Colorectal CD4+ T Cells and Circulating α4β7 Integrin CD4+ T cells : Implications for HIV Microbicides


Autoria(s): Mukhopadhya, Indrani; Murray, Graeme I; Duncan, Linda; Yuecel, Raif; Shattock, Robin; Kelly, Charles; Iannelli, Francesco; Pozzi, Gianni; El-Omar, Emad; Hold, Georgina; Hijazi, Karolin
Contribuinte(s)

University of Aberdeen, Medicine, Medical Sciences & Nutrition, RINH

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Applied Medicine

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Medical Education

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Dental Education

Data(s)

05/08/2016

05/08/2016

28/07/2016

Resumo

This work was supported by the European Union's Seventh Framework Programme for research, technological development and demonstration under grant agreement No 305316 as part of the MOTIF (Microbicides Optimisation Through Innovative Formulation for Vaginal and Rectal Delivery) project. We would like to extend our thanks to all the study participants for their invaluable contribution and to Grampian Biorepository staff for help with collection of fresh colorectal resection tissue.

Peer reviewed

Postprint

Identificador

Mukhopadhya , I , Murray , G I , Duncan , L , Yuecel , R , Shattock , R , Kelly , C , Iannelli , F , Pozzi , G , El-Omar , E , Hold , G & Hijazi , K 2016 , ' Transporters for Antiretroviral Drugs in Colorectal CD4+ T Cells and Circulating α4β7 Integrin CD4+ T cells : Implications for HIV Microbicides ' Molecular Pharmaceutics . , 10.1021/acs.molpharmaceut.6b00351

1543-8384

PURE: 69579576

PURE UUID: 140d70fc-df46-49e2-b831-af775523e5ca

http://hdl.handle.net/2164/7219

http://dx.doi.org/10.1021/acs.molpharmaceut.6b00351

Idioma(s)

eng

Relação

Molecular Pharmaceutics

Direitos

“This document is the Accepted Manuscript version of a Published Work that appeared in final form in Molecular Pharmaceutics, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see [insert ACS Articles on Request author-directed link to Published Work, see http://pubs.acs.org/page/policy/articlesonrequest/index.html].”

Palavras-Chave #efflux drug transporters #uptake drug transporters #gene expression #CD4+ T cells #α4β7 integrin #colorectal mucosa #R Medicine #R
Tipo

Journal article