Identification of Spongionella compounds as cyclosporine A mimics


Autoria(s): Sánchez, Jon Andoni; Alfonso, Amparo; Leirós, Marta; Alonso, Eva; Rateb, Mostafa E; Jaspars, Marcel; Houssen, Wael E; Ebel, Rainer; Tabudravu, J; Botana, Luís M
Contribuinte(s)

University of Aberdeen, Natural & Computing Sciences, Chemistry

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Medical Sciences

Data(s)

05/08/2016

05/08/2016

01/05/2016

Resumo

Acknowledgements The research leading to these results has received funding from the following FEDER cofounded-grants. From CDTI and Technological Funds, supported by Ministerio de Economía y Competitividad, AGL2012-40185-CO2-01, AGL2014-58210-R, and Consellería de Cultura, Educación e Ordenación Universitaria, GRC2013-016, and through Axencia Galega de Innovación, Spain, ITC-20133020 SINTOX. From CDTI under ISIP Programme, Spain, IDI-20130304 APTAFOOD. From the European Union’s Seventh Framework Programme managed by REA—Research Executive Agency (FP7/2007-2013) under grant agreement 312184 PHARMASEA. We wish to thank the Clínica Losada Arránz, especially Ms. Paula López Arránz for providing the human blood samples for T cells purification. Jon Andoni Sánchez is supported by a fellowship from Plan Galego de Investigación e Crecemento, Xunta de Galicia, Spain.

Peer reviewed

Postprint

Formato

8

Identificador

Sánchez , J A , Alfonso , A , Leirós , M , Alonso , E , Rateb , M E , Jaspars , M , Houssen , W E , Ebel , R , Tabudravu , J & Botana , L M 2016 , ' Identification of Spongionella compounds as cyclosporine A mimics ' Pharmacological Research , vol 107 , pp. 407-414 . , 10.1016/j.phrs.2016.03.029

1043-6618

PURE: 68505758

PURE UUID: f9724937-625b-4101-914e-857103fcd0fa

PubMed: 27041481

http://hdl.handle.net/2164/7133

http://dx.doi.org/10.1016/j.phrs.2016.03.029

Idioma(s)

eng

Relação

Pharmacological Research

Direitos

© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/

Palavras-Chave #calcineurin #NFATc1 #lymphocyte #Spongionella #cyclophilin A #IL-2 #RM Therapeutics. Pharmacology #RM
Tipo

Journal article