The Hippo effector TAZ (WWTR1) transforms myoblasts and its abundance is associated with reduced survival in embryonal rhabdomyosarcoma


Autoria(s): Mohamed, Abdalla; Sun, Congshan; De Mello, Vanessa; Selfe, Joanna; Missiaglia, Edoardo; Shipley, Janet; Murray, Graeme I; Zammit, Pete S; Wackerhage, Henning
Contribuinte(s)

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Medical Sciences

University of Aberdeen, Medicine, Medical Sciences & Nutrition

University of Aberdeen, University of Aberdeen

University of Aberdeen, East Bio

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Applied Medicine

Data(s)

05/08/2016

05/08/2016

17/05/2016

Resumo

Acknowledgements This study was funded by Sarcoma UK, Friends of Anchor and the Medical Research Council grant number 99477 awarded to HW and PSZ. This work was also supported, in part, by NHS funding to the NIHR Biomedical Research Centre at The Royal Marsden and the Institute of Cancer Research, and the Chris Lucas Trust, UK. We also thank the CCLG Tissue Bank for access to samples, and contributing CCLG centres, including members of the ECMC paediatric network. The CCLG Tissue Bank is funded by Cancer Research UK and CCLG. In addition we would like to thank Prof KunLiang Guan and Prof Malcolm Logan for kindly providing constructs

Peer reviewed

Postprint

Identificador

Mohamed , A , Sun , C , De Mello , V , Selfe , J , Missiaglia , E , Shipley , J , Murray , G I , Zammit , P S & Wackerhage , H 2016 , ' The Hippo effector TAZ (WWTR1) transforms myoblasts and its abundance is associated with reduced survival in embryonal rhabdomyosarcoma ' The Journal of pathology . , 10.1002/path.4745

0022-3417

PURE: 65963588

PURE UUID: 2d033597-fb85-41a8-9edb-aadd5e132f8e

http://hdl.handle.net/2164/7044

http://dx.doi.org/10.1002/path.4745

Idioma(s)

eng

Relação

The Journal of pathology

Direitos

“This is a preprint of an article published in [include the complete citation information for the final version of the Contribution as published in the print edition of the Journal]” No embargo, on publication

Palavras-Chave #hippo pathway #TAZ #WWTR1 #embryonal rhabdomyosarcoma #R Medicine #R
Tipo

Journal article