Copper complexes as a source of redox active MRI contrast agents


Autoria(s): Dunbar, Lynsey; Sowden, Rebecca J.; Trotter, Katherine D.; Taylor, Michelle K.; Smith, David; Kennedy, Alan R.; Reglinski, John; Spickett, Corinne M.
Data(s)

2015

Resumo

The study reports an advance in designing copper-based redox sensing MRI contrast agents. Although the data demonstrate that copper(II) complexes are not able to compete with lanthanoids species in terms of contrast, the redox-dependent switch between diamagnetic copper(I) and paramagnetic copper(II) yields a novel redox-sensitive contrast moiety with potential for reversibility.

Formato

application/pdf

Identificador

http://eprints.aston.ac.uk/26489/1/Copper_complexes_as_a_source_of_redox_active_MRI_contrast_agents.pdf

Dunbar, Lynsey; Sowden, Rebecca J.; Trotter, Katherine D.; Taylor, Michelle K.; Smith, David; Kennedy, Alan R.; Reglinski, John and Spickett, Corinne M. (2015). Copper complexes as a source of redox active MRI contrast agents. BioMetals, 28 (5), pp. 903-912.

Relação

http://eprints.aston.ac.uk/26489/

Tipo

Article

PeerReviewed