MARK-AGE biomarkers of ageing
| Data(s) |
01/11/2015
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| Resumo |
Many candidate biomarkers of human ageing have been proposed in the scientific literature but in all cases their variability in cross-sectional studies is considerable, and therefore no single measurement has proven to serve a useful marker to determine, on its own, biological age. A plausible reason for this is the intrinsic multi-causal and multi-system nature of the ageing process. The recently completed MARK-AGE study was a large-scale integrated project supported by the European Commission. The major aim of this project was to conduct a population study comprising about 3200 subjects in order to identify a set of biomarkers of ageing which, as a combination of parameters with appropriate weighting, would measure biological age better than any marker in isolation. |
| Formato |
application/pdf |
| Identificador |
http://eprints.aston.ac.uk/25487/1/MARK_AGE_biomarkers_of_ageing.pdf Bürkle, Alexander; Moreno-Villanueva, María; Bernhard, Jürgen; Blasco, María; Zondag, Gerben; Hoeijmakers, Jan H.J.; Toussaint, Olivier; Grubeck-Loebenstein, Beatrix; Mocchegiani, Eugenio; Collino, Sebastiano; Gonos, Efstathios S.; Sikora, Ewa; Gradinaru, Daniela; Dollé, Martijn; Salmon, Michel; Kristensen, Peter; Griffiths, Helen R.; Libert, Claude; Grune, Tilman; Breusing, Nicolle; Simm, Andreas; Franceschi, Claudio; Capri, Miriam; Talbot, Duncan; Caiafa, Paola; Friguet, Bertrand; Slagboom, P. Eline; Hervonen, Antti; Hurme, Mikko and Aspinall, Richard (2015). MARK-AGE biomarkers of ageing. Mechanisms of Ageing and Development, 151 , pp. 2-12. |
| Relação |
http://eprints.aston.ac.uk/25487/ |
| Tipo |
Article PeerReviewed |
