NADPH oxidase signaling and cardiac myocyte function


Autoria(s): Akki, Ashwin; Zhang, Min; Murdoch, Colin; Brewer, Alison; Shah, Ajay M.
Data(s)

01/07/2009

Resumo

The NADPH oxidase family of enzymes has emerged as a major source of reactive oxygen species (ROS) that is important in diverse cellular functions including anti-microbial defence, inflammation and redox signaling. Of the five known NADPH oxidase isoforms, several are expressed in cardiovascular cells where they are involved in physiological and pathological processes such as the regulation of vascular tone, cell growth, migration, proliferation, hypertrophy, apoptosis and matrix deposition. This article reviews current knowledge regarding the role of NADPH oxidases in cardiomyocyte function in health and disease. © 2009 Elsevier Inc. All rights reserved.

Formato

application/pdf

Identificador

http://eprints.aston.ac.uk/21046/1/NADPH_oxidase_signaling_and_cardiac_myocyte_function.pdf

Akki, Ashwin; Zhang, Min; Murdoch, Colin; Brewer, Alison and Shah, Ajay M. (2009). NADPH oxidase signaling and cardiac myocyte function. Journal of Molecular and Cellular Cardiology, 47 (1), pp. 15-22.

Relação

http://eprints.aston.ac.uk/21046/

Tipo

Article

PeerReviewed