Preparation of 9-substituted pyridine-stretched adenines and hypoxanthines

Autoria(s): Crawford, Julia A.; Fraser, William; Ramsden, Christopher A.
Data(s)

01/04/2009
Resumo

9-Methylsulfanyl pyridine-stretched adenine and hypoxanthine derivatives have been prepared via regioselective reaction of a 5-aminoimidazole with 2-(bis-methylsulfanylmethylene)malononitrile [(NC)C=C(SMe) ]. The 9-methylsulfanyl substituent can be replaced by sequential oxidation and substitution by nucleophiles including amines.
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Identificador

http://eprints.aston.ac.uk/19284/1/Preparation_of_9_substituted_pyridine_stretched_adenines_and_hypoxanthines.pdf

http://eprints.aston.ac.uk/19284/2/2009S1271_Crawford_Preparation_of_9_substituted_pyridine_stretched_adenines_and_hypoxanthines.pdf

Crawford, Julia A.; Fraser, William and Ramsden, Christopher A. (2009). Preparation of 9-substituted pyridine-stretched adenines and hypoxanthines. Synthesis, 2009 (8), pp. 1271-1278.
Relação

http://eprints.aston.ac.uk/19284/
Tipo

Article

PeerReviewed
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